Recent design strategies for polymeric adsorbents which remove per- and polyfluoroalkyl substances (PFAS) from water have relied on coupling both electrostatic and fluorine-fluorine interactions with PFAS in fluorinated polymer adsorbents. Non-fluorinated polymers are a desirable alternative to reduce cost and reliance on fluorinated precursors. Molecular design of fluorine-free adsorbents requires development of chemically modular synthetic strategies to uncover new, useful structure-property relationships. We utilize a modular synthetic platform using active ester click chemistry to prepare a library of PFAS adsorbents containing a wide range of Lewis base ligands alongside both hydrophilic and hydrophobic co-monomers. Poly(ethylene glycol) diacrylate networks containing both aliphatic groups and strong bases such as piperazine and piperidine exhibit rapid removal of >98% perfluroooctanoic acid (PFOA) from dilute solutions and can be regenerated using light alcohols. PFOA binding capacities are as high as 910 mg/g despite these materials having lower effective fixed charge densities than commercial anion exchange polymers. Sorption behavior is strongly influenced by ligand basicity and equilibrium pH which alter protonation of PFOA and Lewis base ligands. Notably, the highest sorption capacities are achieved when most PFOA was sorbed in neutral form rather than the anionic form, indicating a new potential route for optimizing PFAS adsorbents.

Background: Information regarding mortality associated with standing procedures in horses is sparse. Objectives: To report data from > 12,000 standing sedations. Study design: Confidential, observational, prospective, multicentre, cohort study. Methods: Approved by the Ethical Committee of the Association of Veterinary Anaesthetists (2020-009), we collected records of horses/ponies undergoing standing sedation for surgery or advanced imaging using at least one top-up or constant rate infusion (CRI). Procedures were either NON-COLIC or COLIC. Outcome at seven days was recorded as i) ALIVE, ii) EUTHANASIA or iii) DEAD. Data were collected with a PDF questionnaire, which evolved into a webpage and processed with the statistical software R. Results: Data were collected from 12,307 standing sedations in 61 centres in 23 countries. Death rates were 0.15% overall (19/12,307), 0.13% for NON-COLICs (16/12,237) and 4.29% for COLICs (3/70). The causes of death in the 16 NON-COLICs were abdominal in ten (62.5%), fracture/refracture in three (18.75%), two were “found dead” (12.50%) and one (6.25%) for “other reasons”. In most cases premedication consisted of combinations of alpha-2-agonists/opioids with or without acepromazine. Sedation was maintained using top-ups (9,668/12,307), CRI (3,795/12,307) or CRI + top-up (1,156/12,307). Detomidine was the alpha2-agonist most frequently used for top up (8,258/12,307) and butorphanol the most common opioid (2,754/12,307). Detomidine was the most frequently used alpha-2-agonist for CRI (3,231/12,307); 364 and 305/12,307 received butorphanol and morphine respectively. Only 24.22% received fluid therapy. Locoregional anaesthesia was performed in 37.6% of the cases. Monitoring was minimal, with temperature (5.8%), ECG (3.8%) and pulse-oximetry (0.9%). Main limitations: Sample size, selection bias, questionnaire initially designed for general anaesthesias, potential human errors for data entry and potential missing cases.  Conclusions: Standing sedation in horses is not risk free. Horses die unexpectedly within seven days of sedation. Efforts should be made to reduce these mortality rates further.

A document by Dipendra Shahi. Click on the document to view its contents.

Oxytocin (OXT), a neuropeptide produced in the paraventricular nucleus (PVN) of the hypothalamus, regulates social behavior, stress responses, and memory. Our previous studies demonstrated that intracerebroventricular administration of OXT ameliorates amyloid-β–induced cognitive deficits and that selective activation of PVN OXT neurons enhances memory performance. These findings suggest that endogenous OXT secretion is essential for normal memory processing and that its impairment may lead to cognitive dysfunction. To test this hypothesis, we generated oxytocin neuron-specific conditional knockout (cKO) mice for the Ca²⁺-dependent activator protein for secretion 2 (CAPS2) by crossing Caps2-floxed mice with oxytocin-iCre mice. In these mice, OXT exocytosis was selectively impaired in OXT neurons. Behavioral analyses revealed that Caps2 cKO mice exhibited deficits in long-term memory in the novel object recognition (NORT) and passive avoidance tests, whereas short-term spatial memory assessed by the Y-maze test remained unaffected. Electrophysiological recordings further showed that hippocampal long-term potentiation was markedly attenuated in Caps2 cKO mice. Consistently, phosphorylated ERK levels in the ventral hippocampus were significantly reduced following the NORT. These findings demonstrate that CAPS2-dependent OXT release is critical for long-term memory formation and hippocampal synaptic plasticity. Our results provide new insight into the physiological role of endogenous OXT signaling in cognitive function and suggest its potential relevance to the pathogenesis of memory disorders such as Alzheimer’s disease.

Accurate runoff inversion is essential for watershed hydrology and water resources management, yet traditional single-model approaches often exhibit substantial biases in complex terrain and nonlinear flow regimes. This study presents a fusion modeling framework for the Jialing River Basin, combining three individual methods—the relationship fitting method, the improved Manning’s formula, and the C/M signal method—through weighted averaging, Bagging–AdaBoost, and Stacking ensemble strategies, with linear regression as a meta-learner for multi-source feature integration. Validation using monthly data from 2015–2020 shows that the Stacking-based model achieves superior performance (Nash–Sutcliffe efficiency = 0.981; RMSE = 38.69 m 3/s; RRMSE = 5.09%), outperforming both Bagging–AdaBoost and weighted averaging. The model effectively reduces systematic errors and variance, providing stable predictions across high- and low-flow regimes. These results demonstrate that ensemble-based fusion models significantly enhance runoff reconstruction and capture flow dynamics more accurately than individual approaches. The proposed framework offers a robust, scalable tool for hydrological estimation in complex basins and has important implications for water resources management and flood mitigation.

A Simulation Study of Forces Applied to Managing an Impacted Fetal Head: A Review and CommentaryAuthor: Lawrence DevoeAffiliation: Medical College of Georgia, Obstetrics & GynecologyCorresponding Author: Lawrence Devoe. ORCID ID: 0000-0003-1026-8388Funding Statement: No funds were used in writing this reportConflicts of Interest Disclosure: No conflicts of interest were identifiedEthics Approval Statement: No ethics approval was required for this reportA deeply impacted fetal head in the second stage of labor presents significant management challenges for obstetricians wishing to avoid serious fetal and maternal complications at the time of cesarean delivery (CD) (Peak AG et al. Techniques for managing an impacted fetal head at cesarean section: A systematic review. Eur J Obstet Gynecol Reprod Biol 2023 Feb 281: 12-22). However, a debate persists about the optimal approach to disimpaction techniques (Jeve YB et al. Comparison of techniques used to deliver a deeply impacted head at full dilation: a systematic review and meta-analysis. BJOG. 2016 Feb; 123: 337-45). When a decision is made to manually disimpact a fetal head, a major issue is the amount of force applied by the obstetrician to accomplish this procedure successfully and safely.The present study (Xue Y et al. Characterising forces applied during the simulatedmanagement of impacted fetal head: pre-clinical methods study. BJOG.In press )returns to the drawing board to address this issue. The investigators developed a simulation model that provided participants with surgical gloves fitted with sensors distributed along fingertips, palmar and dorsal surfaces while two additional pairs of gloves were worn above and below the sensorized pair. These sensors enabled measurements of all the forces applied by the study participants and showed the greatest consistency and highest maximal forces applied at the fingertips. While only one of the thirteen participants failed to disimpact the model head, there was considerable variability in the amount of force applied by the successful participants.Xue et al. concluded that they found the sensor glove was useful for training. However, I am not entirely certain how they reached this conclusion, particularly in view of the participants’ recommendations that future sensors should be made wireless and fewer plain gloves be employed. Moreover, the authors readily admit that future work is needed that includes direct comparisons of subjective estimates of applied forces with those actually measured. The authors also mention the need for an assessment of changes in participant confidence and skill after repeated uses of both active and inactive gloves. They also note that the position of the fetal head was always in occiput anterior and future trials with other fetal head positions should be considered.This report provides novel and potentially useful information for designing and deploying a low-risk training platform for obstetricians at all levels of training and experience to optimize their practices when encountering this delivery complication. While simulation is not a “real life” situation, the feedback that the participants in this study received regarding technique and applied forces could well help them to improve their handling of this clinical scenario in the future.

Key Clinical MessageHaemodynamically significant aortic regurgitation (AR) can be underestimated by standard echocardiography and 2D phase-contrast CMR, particularly in patients with heart rate variability. This case highlights the additive role of 4D-flow CMR in reclassifying AR severity from mild-moderate to moderate-severe. Accurate quantification is essential to identify AR as the primary driver of cardiomyopathy, explaining adverse remodelling and guiding timely aortic valve intervention to prevent irreversible myocardial fibrosis.Case DescriptionA 73-year-old female was admitted to the hospital with progressive shortness of breath. Her medical history was notable for breast cancer, treated successfully 19 years prior. She was diagnosed with acute decompensated heart failure and treated acutely with intravenous furosemide.Initial investigations revealed a significantly elevated NT-proBNP of 5772 ng/L (normal range <400). The electrocardiogram showed sinus rhythm with a narrow QRS complex. A transthoracic echocardiogram (TTE) demonstrated a dilated left ventricle (LV) with severe global systolic dysfunction (estimated ejection fraction [EF] 10–20%). The TTE also identified moderate aortic regurgitation (AR), though the aortic valve appeared morphologically normal with normal aortic dimensions. Prior to discharge, she was initiated on guideline-directed medical therapy (GDMT) including bisoprolol, ramipril, spironolactone, and dapagliflozin.To further investigate the aetiology of her non-ischaemic cardiomyopathy, an outpatient cardiac magnetic resonance (CMR) study was performed two months after her index admission. The CMR confirmed severe LV dilation (end-diastolic volume index 159 ml/m²) and severe systolic dysfunction (LVEF 26%) (Fig. 1). The right ventricle (RV) was normal in size but had impaired systolic function (RVEF 41%).AR severity analysis with standard 2D phase-contrast quantification indicated mild-to-moderate AR (regurgitant fraction [RF] 20%, regurgitant volume [RVol] 10.9 ml) (Fig. 1A – 1B). In contrast, advanced 4D-flow analysis provided a critical diagnostic revision, demonstrating moderate-to-severe AR (RF 38%, RVol 20 ml) (Fig. 1C - 1F).Furthermore, tissue characterisation provided evidence of established adverse remodelling. There was diffuse myocardial fibrosis (elevated native T1 and extracellular volume) and subtle mid-wall late gadolinium enhancement (LGE), representing the chronic sequelae of chronic volume overload.

A new perspective on Torquetenovirus DNAemia as a biomarker of immunosuppression and inflammationDavid Navarro1,2,31Microbiology Service, Clinic University Hospital, INCLIVA Health Research Institute, Valencia, Spain.2CIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain.3Department of Medicine, School of Medicine, University of Valencia, Valencia, Spain.*Correspondence:David Navarro, Microbiology Service, Hospital Clínico Universitario, Instituto de Investigación INCLIVA, Av. Blasco Ibáñez 17, 46010 Valencia, Spain. Phone: 34(96)1973500; Fax: 34(96)3864173; Email: david.navarro@uv.es.Torquetenovirus (TTV) is a prototypical Anelloviridae species belonging to the genus Alphatorquevirus , which comprise small, non-enveloped particles harboring a single-stranded circular DNA genome of approximately 3,800 nucleotides in length containing at least four overlapping open reading frames (ORFs).1 Most individuals become infected with TTV early in childhood, leading to a lifelong persistent infection at multiple body sites, although no disease has been directly attributed to it;2 in fact, TTV is a highly abundant component of the human virome in healthy individuals and as such viral DNAemia is frequently measurable.3,4 TTV replication in humans is strictly controlled by T-cell–dependent effector mechanisms, which explains the relative stability of viral loads in blood in immunocompetent subjects.5 In contrast, TTV DNA load fluctuates widely in immunosuppressed individuals, such as solid organ transplant (SOT) recipients, showing a clear direct relationship between the magnitude of plasma viral loads and the degree of immunosuppression.6.7 In this sense, peripheral blood TTV DNA load behaves as an “immunometer” in SOT patients, as low viral loads may anticipate allograft rejection, whereas high viral loads may predict the occurrence of infectious events.6,7In non-canonically immunosuppressed populations, such as the elderly, TTV DNA loads are substantially higher compared with younger adults, and their magnitude has been associated with physical frailty and increased mortality risk, thus serving as a marker of immunosenescence.8 Data obtained from in vitro models indicate that TTV may stimulate inflammatory responses; conversely, pro-inflammatory conditions may enhance TTV replication.6 In this context, high plasma TTV DNA loads have been reported in individuals with chronic inflammatory lung disorders—such as asthma, chronic bronchiectasis, or chronic obstructive pulmonary disease—as well as in Crohn’s disease, when compared with healthy individuals.2,8 Moreover, elevated TTV DNAemia has been observed in patients with systemic inflammation, including those with bacterial sepsis or COVID-19.8Alphatorquevirus species exhibit extensive genetic diversity. Based on sequence identity within the ORF1 coding region, at least 20 human-infecting TTV species—which may co-exist within a single individual—have been identified. While certain species appear to be more prevalent in specific clinical contexts (e.g., TTV3, TTV5, and TTV9 in immunocompromised patients, or TTV1 and TTV2 in autoimmune disorders), the clinical relevance, if any, of TTV species diversity remains largely unknown.In this context, a recent study published in the Journal of Medical Virology by Novazzi and colleagues postulates, for the first time, that TTV species diversity may represent a novel marker of immune dysregulation in the elderly.9 The authors collected peripheral blood samples from 300 randomly selected, age-stratified adults as part of a multicenter European project primarily aimed at identifying biomarkers of human aging. Participants were grouped into three categories based on their age, degree of immunocompetence as inferred from the CD4/CD8 ratio and CMV IgG levels, and their overall inflammatory status as determined by several ad-hoc biomarkers such as C-reactive protein (CRP), α-2 macroglobulin, ferritin, ceruloplasmin and the neutrophil-to-lymphocyte ratio, among others.Three cohorts were established: cohort A consisted of seemingly immunocompetent young adults (35–45 years) with no signs of increased inflammation; cohort B comprised older individuals (65–75 years) displaying mildly reduced immunocompetence and low levels of inflammatory markers; and cohort C included aged individuals (65–75 years) with signs of immunosenescence and a relatively high inflammatory status.In addition to quantifying TTV DNA load in plasma samples using a laboratory-developed universal TTV assay, the authors employed a short-read next-generation sequencing approach (Illumina) to assess intra-host TTV species diversity. Interestingly, cohort C exhibited significantly greater richness and diversity compared with cohorts A and B, while these parameters did not differ substantially between cohorts A and B. Importantly, certain TTV species were associated with decreased CD4 and NK cell percentages, a low CD4/CD8 ratio, and a reduction in the number of T-cell receptor excision circles—all hallmarks of immunosenescence. Moreover, some TTV species appeared to be more prevalent in cohort C individuals compared with the other two cohorts, and notably, a direct correlation was found between the number of detected TTV species and age, degree of immune impairment, and TTV load. Additional evidence linking TTV species diversity to immune aging and inflammation was provided by experiments analyzing the association between TTV species diversity and PARP-1 (poly[ADP-ribose] polymerase-1) activity, as measured by flow cytometry (fluorescence-activated cell sorting). In these experiments, the activity of PARP-1—a key cellular stress regulator and strong promoter of inflammation10—was found to be increased in individuals displaying a higher number of TTV species. Finally, although no consistent association was found between species diversity and levels of inflammatory biomarkers, TTV DNA load was directly correlated with CRP and α-2-macroglobulin levels. From a mechanistic standpoint, the authors propose that the relationship between species diversity and age-related immune dysregulation may reflect decreased immune pressure, which would pave the way for the expansion of better-adapted TTV species with enhanced replication capacity or immunoevasion properties. Nevertheless, an enhanced direct pathogenetic effect of certain TTV species over others on immune homeostasis cannot be ruled out.An important drawback of the study is that sequential monitoring of TTV species diversity was not performed; plausibly, TTV species richness or diversity may vary over time even in non-severely immunosuppressed individuals. Despite the limitations of the study—clearly acknowledged by the authors—it paves the way for incorporating TTV species profiling into the toolbox of studies aiming to predict the risk of age-associated diseases pathogenetically linked to immunosenescence and systemic inflammation. Nevertheless, as the authors point out, well-powered prospective longitudinal studies are needed to validate this assumption.

Captive culturing of coral is required to supply a burgeoning aquarium trade and potentially supply populations to replenish reefs that have been degraded globally due to anthropogenic impacts. High-density coral propagation can be compromised by pests that reduce broodstock and offspring health. Acropora-eating flatworms (Prosthiostomum acroporae) are parasitic polyclads that often evade visual detection and feed on tissues of branching coral species of the genus Acropora, which are key targets for coral aquaculture production. We developed a highly sensitive and specific droplet digital PCR (ddPCR) assay to detect environmental DNA (eDNA) of P. acroporae from water samples, with the limit of detection of 2.3 copies of the mitochondrial cytochrome c oxidase subunit I gene per ddPCR reaction. Validation was performed using water samples of aquaria holding Acropora corals suspected to be affected by P. acroporae, and the sequence identity of ddPCR amplicons confirmed by Sanger sequencing. P. acroporae eDNA was detected in some cases without visual confirmation of P. acroporae, indicating this assay can detect early infestations of P. acroporae that are not evident through visual monitoring. This study demonstrates that the ddPCR assay can be a valuable tool for monitoring pests in coral aquaculture systems and subclinical detection of parasitic infestations.

Arthropods are traditionally viewed as invertebrate prey and predators for vertebrates, a paradigm increasingly challenged, especially among arachnids. While spiders are documented frog predators, the capacity of other groups like harvestmen (Opiliones) has remained anecdotal. We report novel field observations of anuran predation by multiple Cranaidae harvestmen species across Neotropical localities. These records include active capture and consumption of live frogs, demonstrating their role as opportunistic mesopredators. Alongside new spider predation records, our findings substantially advance Opiliones ecology by confirming vertebrate predation occurs in multiple, disjunct species. This reveals vertebrate consumption among arachnids is more taxonomically widespread than recognized, underscoring the need to include Opiliones as potential predators in Neotropical trophic models.

As urbanization continues to accelerate, human-dominated habitats are becoming increasingly important for wildlife as some species of conservation concern move into urban landscapes. In response to the widespread loss or conversion of their preferred wetland habitat, Black-crowned Night Herons (Nycticorax nycticorax; BCNH) frequently nest in urban areas. Despite being the most widely distributed colonial wading bird in the world, BCNH face population declines and have been listed as a special-status species in 11 U.S. states and Ontario, Canada. The largest remaining BCNH rookery in the Great Lakes region of the U.S. is located at Lincoln Park Zoo in Chicago, Illinois. Although nesting in an urban center is inherently risky, this colony appears to be thriving. We used GPS/GSM satellite transmitters to better understand the home range size, habitat use, and activity patterns of individual birds during the breeding season. We found that BCNH foraged in a wide variety of natural and highly modified waterbodies and exhibited distinct behavioral differences between breeding and non-breeding birds. Non-breeding birds’ home ranges were on average 18 times larger than those of breeding birds, which primarily foraged within 10 km of the colony, while non-breeding birds ranged widely but continued to use relatively urban habitats. All birds were active throughout the 24-hour period, but breeding BCNH showed higher activity rates than non-breeding birds throughout the diel cycle. Understanding the behavior of this declining species within urban landscapes can improve our understanding of this species’ ecology and provide valuable insights to inform management and conservation efforts.

Field measurements within ice covers during the melting period are scarce, often constrained by safety concerns leading to uncertainty in model parameterizations of ice melt. To address these limitations, a Floating Research Station (FRS) was constructed in a small subarctic lake near Yellowknife, Canada to monitor ice processes year-round. Using the FRS, the objective of this study was to delineate key processes influencing ice melt and decay through evaluating heat budget components over three melt seasons: April 1- May 31 of 2023, 2024, and 2025. Our results show that the decay process was both thermally and mechanically driven, with mechanical decay from ice collapse occurring at internal ice porosities of 0.31-0.35 and accounting for 24 - 48% of total ice loss. Thermal melt at the surface (0.6 - 2.1 cm d -1) was driven by surface heat absorption (13-160 W m -2) and losses via net longwave fluxes (-95.2 - -6.6 W m -2). Bottom melt (0.1- 0.6 cm d -1) was caused by modest mean daily water-to-ice heat fluxes (< 15 W m -2). Melt season lengths varied between 35-49 days, and break-up dates up to 16 days, and were dependent on air temperatures, albedo, and net insolation. Results from this study can be used to improve and constrain melt period parameterizations in ice models while providing needed validation and calibration data in northern, high-latitude environments.

TemplateCorrection to “Aggressive Disease and Poor Clinical Outcome in CEBPα-Mutated Acute Myeloid Leukemia Patient”A. A. Alshammari, M. O. AlSabbagh, H. M. Alshehri, A. F. AlSwayyed, F. M. Alseraye, and A. A. Peer-Zada, “ Aggressive Disease and Poor Clinical Outcome in CEBPα-Mutated Acute Myeloid Leukemia Patient,” Clinical Case Reports  13, no. 11 (2025): e71462, https://doi.org/10.1002/ccr3.71462.In the published version of this article, the author name was incorrect. The name appeared as: Attatullah A. Alshammari . It should read: Abdullah Attullah Alshammari .]We apologize for this error.

2-Trifluoromethylated aromatic azacycles such as quinoline and pyridine derivatives are interesting targets for the development of new drugs and agrochemicals. The direct C-H trifluoromethylation of aromatic azacycles using trimethyl(trifluoromethyl)silane (TMSCF 3) constitutes a facile approach for the C2-regioselective incorporation of a trifluoromethyl group into aromatic azacycles, but the yield and substrate scope wait for further improvement. Herein, we report an improved C2-regioselective trifluoromethylation of quinoline derivatives using Me 2(CH 2Cl)SiCF 3. Under a modified condition of Kanai & Kuninobu procedure involving sequential nucleophilic addition/oxidative aromatization process, an array of 2-CF 3 substituted quinoline derivatives (24 examples) could be obtained in good to excellent yields, obviously higher than those obtained by using TMSCF 3 (the yield increment of 10 examples was no less than 20%). Obviously enhanced yield is also observed in the 2-trifluoromethylation of naphthyridine and phenanthroline derivatives. These results imply that modifying the methyl group of TMSCF 3 by a suitable polar substituent may contribute to more powerful silyl trifluoromethylating reagents for the selective incorporation of a CF 3 group into aromatic azacycles.

1. Environmental pressures, particularly those driven by anthropogenic activity, can induce rapid behavioural and physiological adaptation. Insects, due to their ecological importance, are especially affected by the widespread use of insecticides. While physiological resistance to insecticides is well documented, less is known about how such resistance influences behaviour, particularly oviposition site choice, a decision with direct consequences for offspring survival. 2. Using Drosophila melanogaster, we investigated whether genetic resistance conferred by the detoxification gene Cyp6g1 affects oviposition preferences and survival across life stages when exposed to insecticides. We presented resistant and susceptible female flies with a choice between food laced with acetone, insecticides to which they are resistant to, or insecticides to which Cyp6g1 does not confer resistance, and examined larval and adult survival under matching exposure conditions. 3. We found that resistant females differ from susceptible flies by avoiding laying eggs on food containing DDT, an insecticide they are resistant to, suggesting that resistance is associated with a parallel shift in behaviour. Larval survival was closely tied to maternal oviposition choice, with Cyp6g1-mediated resistance conferring survival benefits only against insecticides it can detoxify. In contrast, adult survival was less affected by genotype, highlighting the importance of oviposition site selection in shaping transgenerational fitness. 4. Our results suggest that resistance alleles can impact not only physiological resistance but also incur behavioural adaptations such as toxin avoidance that act synergistically to mitigate insecticide exposure. 5. Furthermore, our results show that these resistance alleles influence behaviour in ways that affect their frequency in natural populations.

Wernicke–Korsakoff syndrome a rare complication of hyperemesis gravidarum: case report.

Dr Dorothy Tse is a Reader in the Department of Psychology at Edge Hill University. She completed her PhD at the University of Edinburgh and is recognised for her research on the neurobiology of memory, with a particular focus on how prior knowledge (schemas) and novelty shape memory networks, and previously shared some of this work through EJN (Benoy & Tse, 2025; Broadbent et al., 2020). Her work has advanced our understanding of how new information is assimilated into existing schemas. More recently, she has used approaches including translational behavioural paradigms, virtual reality, and mobile EEG to develop tools that support healthy ageing. Dr Tse has received the Academy of Medical Sciences Springboard Award and the Alzheimer’s Research UK Inspire Fund, and she was selected to join the prestigious FENS-Kavli Network of Excellence. She also serves as Co-Chair of the Programme Committee for the British Neuroscience Association (BNA) 2025 and 2027 International Festival of Neuroscience and is the founder of the Liverpool Neuroscience Early Career Researcher Group. Beyond academia, Dr Tse has led impactful public engagement initiatives such as Healthy Ageing with an Active Mind, co-created with communities and charities. Her work exemplifies a deep commitment to ensuring that neuroscience research not only advances theory but also delivers meaningful societal benefit

TitleLate-Onset Mesalazine-Induced Eosinophilic Pneumonitis Presenting as Non-Resolving Pneumonia: A Diagnostic Pitfall in Ulcerative Colitis