Parkinson’s psychosis refers to psychotic symptoms such as illusions, hallucinations, and delusions that are frequently referred to as ‘positive,’ meaning a benefit. Quetiapine was the most commonly used initial atypical antipsychotic medicine for therapy, followed by Risperidone, Olanzapine, Aripiprazole, and other atypical antipsychotics. According to new research, Pimavanserin may surpass other therapy for older people with Parkinson’s disease (PD) psychosis. Pimavanserin is a powerful inverse agonist with a preference for 5-HT2A receptors over 5-HT2C receptors and no functional activity at a number of G-Protein coupled receptors GPRCs such as dopaminergic, muscarinic, adrenergic, and histaminergic receptors. Pimavanserin had a relative protective effect in 85 percent of the study group of PD patients living in the community.

Fluoroelastomer has received increasing attention for energetic materials application due to its high fluorine contents. Different contents of poly(VDF-ter-HFP- ter- TFE) terpolymer are added into Al/MnO2 nanothermite. The peak exothermic temperature of thermite reaction for Al/MnO2 system is about 554 oC with 1070 Jg-1 heat release. After adding terpolymer, it mainly exists in the gap among Al nanoparticles and MnO2 nanorods, and can react with Al and MnO2 at the range of 350 oC to 540 oC before the occurrence of thermite reaction. 10wt% terpolymer has relatively little effect on the thermite reaction, and for the samples with higher terpolymer content, more nanothermite components reacts with terpolymer at early stage. Ignition and combustion performance show terpolymer can reduce ignition energy threshold by up to 9.82% and increase combustion duration time at least several times. The potential reasons for above results are analyzed. This work can shed light on application of fluoroelastomer in energetic-materials.

Mapping the distribution of ticks and tick-borne pathogens linked to their molecular information from previously unexplored geographic areas provide valuable information about the cryptic tick fauna and their associated pathogens of zoonotic and veterinary importance. The present research was designed to investigate the epidemiologic and phylogenetic aspects of ticks and tick-borne pathogens infesting goats and sheep in the north and north-western territories of Pakistan. A total of 1587 ixodid ticks were collected from goat and sheep herds (n = 600). The collected ticks were taxonomically classified using morphological keys and the molecular markers 16S rRNA and COI. The presence of tick-borne pathogens in collected ticks was assessed by PCR targeting the genetic markers 16S rRNA and gltA for bacterial pathogens, and 18S rRNA for Apicomplexan parasites. The morpho-molecular characterization of hard ticks revealed three ixodid tick genera ( Hyalomma, Haemaphysalis, and Rhipicephalus) which included 11 tick species viz. Hy. anatolicum (5.9%) , Hy. dromedarii (9.1%), Hy. excavatum (2.8%), Hy. isacci (5.1%) , Hy. scupense (7.7%), Hae. montgomeryi (18.3%) , Hae. sulcata (6.5%), Rh. decoloratus (4.4%) , Rh. haemaphysaloides (13.2%) , Rh. microplus (10.8%) , and Rh. turanicus (16.2%). Amplified tick 16S rRNA and COI nucleotide sequences shared 99.74-100% similarity and clustered phylogenetically with similar tick species reported previously in China, India, Iran, Saudi Arabia, Sri Lanka, South Africa, Turkey, and Pakistan. The 16S rRNA , 18S rRNA and gltA nucleotide sequences of detected tick-borne pathogens, including R. massiliae (24.5%) followed by T. ovis (16.4%), A. capra (9.1%), T. luwenshuni (6.4%), A. ovis (5.9%), R. hoogstraalii, (5.0%), Anaplasma spp. (4.5%), Ehrlichia spp. (4.5%), Rickettsia spp. (4.5%), T. annulata (4.1%) and A. marginale (3.6%), shared 99.48-100% similarity and grouped with sequences previously reported in South Asia, middle east Africa and USA. This study showed for the first time the presence of two tick ( Hae. montgomeryi and R. decoloratus) and one tick-borne pathogen species ( R. hoogstraali) in Pakistan. Our results are the first available reports documenting important ticks and tick-borne pathogens of veterinary and public health concern from previously neglected parts of Pakistan. These results could be used as a baseline to facilitate future large-scale epidemiological and molecular studies about ticks and tick-borne pathogens of small ruminants at the local and global levels.

This study analyzed global data and provides insights how economic conditions in various countries associate with epidemic control measures during different epidemic periods by mutant strains. In this study, the elasticity coefficient is estimated through a log-log model, which represents the percent change of the confirmed case number with respect to a percent change of the total number of screening tests in a country for epidemic control. The elasticity estimate was used to show the effectiveness of epidemic control by community screening. The 7-day rolling data of screening tests and confirmed cases from the Our World in Data (OWID) database for the pandemic periods of Alpha strain in 2020, Delta strain in 2021, and Omicron strain in 2022, suggests that the magnitude of the elasticity was associated with the economic condition of a country. Compared with the result s during either Alpha - or Delta- pandemic period, the Omicron pandemic has a much higher estimated elasticity coefficient of 1.317 (Alpha: 0.827 and Delta: 0.885). Further comparison of economic conditions that were classified by quartile ranges, the result reveals the elasticity in countries with GDP per capita between $11,354 and $26,651 or GDP per capita above $26,651 is statistically significantly lower than that in countries having GDP per capita below $3,335. The findings of this study imply that the performance of epidemic control in a country is not only dependent on epidemiological measures applied, but is also influenced by the economic condition of a country.

One of greatest common main cancerous tumor of the brain in adults is glioblastoma, which is fatal without treatment. For individuals diagnosed having glioblastoma, typical gold level treatment consists of surgical removal of the tumor supported by radiation treatment plus concurrent chemotherapy drugs. Despite this, overall, prognostic level is still dismal; approximately 12-to 15-month life expectancy is typical. Cell signaling, angiogenesis, Gene mutation have all been highlighted as promising areas to explore in the lookout for potential treatments, thanks to years of study. The pathophysiology of glioblastoma is now much more complicated due to new discoveries of extrachromosomal DNA (ecDNA). Numerous oncogenes found within those ecDNAs, which seem to be important driving therapeutic resistance, faster tumor progression and intra-tumoral heterogeneity, are also found in cancer cells nucleus, where their genome size is noticeably larger. Existing knowledge regarding therapy significance, tumor growth and ecDNA synthesis in glioblastoma will indeed be reviewed in this article.

Competition and indirect ELISAs are currently being used to monitor rabbit hemorrhagic disease viruses (RHDV1 and RHDV2) in rabbits worldwide. Temporal changes in the sensitivity (Se) and specificity (Sp) of assays were investigated using Bayesian Latent Class models (BCLM) in the Australian wild rabbit population where both viruses circulate simultaneously and a long-term serological dataset exists. When cELISA1 was compared to IgG1 ELISA, the Se of cELISA1 improved while the Sp of IgG1 ELISA declined over the 2011-2021. This corresponded with a decline in the true RHDV1 prevalence in 2018-21, suggesting that a large proportion of RHDV1 exposed rabbits survived the introduction and dominance of RHDV2 up to approximately 2017/2018, after which they died and were not replaced. The Se and Sp estimates for 2014-15 for both cELISA1 and IgG1 ELISA, and the true prevalence when analysing all three tests together were similar to those obtained from the analysis of cELISA1/IgG1. The same was also true for the Se and Sp of cELISA2 and IgG1 estimates from 2018 onwards. This suggests that RHDV1 was the dominant infection status in 2014-15, but RHDV2 was the dominant infection status in 2018-2021. Further, the increase in Se of cELISA2 and the low Sp of IgG1 ELISA in the cELISA2/IgG1 ELISA analysis, compared to the Se of cELISA2 and Sp of IgG1 ELISA when analysing all three tests together suggests that the underlying infection status was more influenced by RHDV2 and that the higher Se of IgG1 ELISA is due to cross-reaction of RHDV2 antibodies on IgG1 ELISA. The true prevalence data suggests that RHDV2 exposure peaked in 2017. Our findings show that test characteristics changed in response to the changing virus prevalences over time. IgG1 ELISA currently has a high Se, should be used to monitor both viruses and will perform better than both cELISAs.

Many of the microorganisms that compose the microbiome of human are favorable or even helpful to the host's health, and this group play a crucial part in the body's physiological functioning. A number of microorganisms, meanwhile, have been related with cancer and other disorders defined mostly by abnormal inflammation and are thus thought to be harmful to human welfare. Cancer is only one of several diseases that may develop as a result of dysbiosis, a microbiological disequilibrium in which hazardous bacteria species compete effectively harmless bacteria. The skin microbiome, the urogenital microbiome and the gut microbiome, are especially clearly defined, although the microbial diversity differs between body locations. Nevertheless, there is little knowledge about the human microbiome and about the way, it relates to both healthy and diseased breasts. According to a variety of research, breast tissue has a unique microbiome, with certain types being elevated in the tissue alone; along with in the gut and nipple aspirate microorganism of the breast cancer patients. In addition, the breast microbiome and its surroundings can influence the treatment reaction and function as conceivable biomarkers in the detection and evaluation of breast cancer at any stage.

14-years old asymptomatic boy with holosystolic murmur heard over the lower left sternal border. Zoomed apical 5 chamber view revealed a perimembranous ventricular septal defect (VSD) which was closed by an aneurysmal leaflet of the tricuspid valve (TV) (Figure A) .Color Doppler across the defect showed left to right shunt (Figure B) Short axis view at the level of the aortic valve showed that VSD was extending from 10 to 11 o’clock . (Figure C). Injection of bubbles showed negative contrast inside the right ventricle indicating incomplete defect closure. (Figure D) 3D Transesophageal Echocardiography (TOE) with zoomed mode showed the entry point from the left ventricular side and exit point from the right ventricular side.(Figure E) En-face viewing of the TV from the right ventricular perspective showed an aneurysm-like pouch formed by the anterior leaflet (Figure F) The left atrial and ventricular size was normal and the shunt ratio was 1.3 so he was treated conservatively. Ventricular septal defect is the most common congenital anomaly.The incidence of spontaneous closure is still undetermined .Different mechanisms for anatomical closure have been proposed such as the adherence of the septal leaflet and/or the anterior leaflet of the tricuspid valve to the margins of the defect forming an aneurysm-like pouch that maybe mistaken for an aneurysm of the membranous septum. Echocardiography is the gold standard for evaluation of the site , size and type of VSD and its relation to the tricuspid valve. Recently, transcatheter closure is feasible and efficacious in properly selected patients.

Background: Coronary artery fistula (CAF) is a congenital connection between a coronary artery and cardiac chambers, or a vessel bypassing a capillary system. The clinical presentation of congenital CAF varies, depending on its size and the draining chamber. Case presentation: A 23-year-old patient without a prior medical history consulted to cardiology clinic with a referral diagnosis of interatrial septal aneurysm and defect. Transthoracic echocardiography revealed a dilated right coronary artery to a sac into the right atrium with dilated right side of the heart. Transesophageal echocardiography provided the calculation of the narrowest part of the fistula where the closure device was planned to be deployed, and two sequential sacs of the fistula on its way to the right atrium. Cardiac computed tomography demonstrated the aneurysmatic dilatation of the proximal portion of the right coronary artery (CA) was 14*20 mm and the narrowest exit of the CAF as 8*8.3 mm width. transcatheter closure of an isolated enormous CAF was decided and surgery left to be reserved for CAF with failed percutaneous closure. Conclusion: Multi-modality imaging take part in the diagnosis and follow-up of the CAFs for identifying the anatomy/physiology, guiding the intervention, supplementary hemodynamic information, assessing the anatomical relationship and ischemia.

Abernethy malformation, also known as congenital extrahepatic shunt, is a rare anomaly characterized by partial or complete diversion of the portal blood into the systemic venous circulation. The clinical manifestations of Abernethy malformation during childhood include neonatal cholestasis, failure to thrive, mental retardation, and other congenital defects. We report a case of Abernethy malformation Type Ⅱ in a 9-year-old boy whose left ventricle was slightly enlarged because of several major aortopulmonary collateral arteries but normal laboratory examinations five years earlier. The characteristics of congenital heart disease in patients with Abernethy malformation are discussed. We propose that enlargement of the left ventricular with systemic-pulmonary collateral circulation should raise the suspicion of Abernethy malformation.

Physical parameters representing the energy components of the cardiac pump related to inertance, resistance, and compliance are developed. The martingale optimality principle and the Malliavin calculus are used to estimate these time-varying parameters. The methods are applied to the ejection phase of the cardiac cycle, using pressure and flow measured at the root of the aorta for the left ventricle. We find the compliance parameter to be in general agreement with data reported by others, but our resistive parameter differs considerably and has a value commensurate with the expected efficiency of the cardiac pump. The inertance parameter, not represented in models reported by others, is shown to be of significance and may contribute to differences in values of the other parameters.

Increases in critical land in the Bengawan Solo River Basin contribute to floods and severe damage to infrastructures along the river channel. Additionally, the occurrence of excessive erosion is a source of sediment materials, especially at meandering sections. Riverbank erosion destabilises dykes and sediment deposition decrease capacity, thereby resulting in floods (especially during rainy seasons). Although both phenomena can be evaluated by observing flow velocity and sediment concentration, there is a paucity of field investigations on parameters that affect erosion under dry and rainy seasons. This study investigates the aforementioned parameters and contrasts circumstances during dry and rainy seasons by presenting relevant information on sediment quantity and flow velocity. The results indicate that sediment concentration at the outer banks of the flow path significantly exceeds that at the inner banks, thereby indicating significant occurrence of erosion. Further examination of riverbed material suggests that the interaction between sediment concentration and flow velocity, especially in meandering segments, can provide an estimate of the erosion rate and the change in the morphology of the alluvial river. Sediment concentration is correlated with seasonal conditions such that sediment concentration during the rainy season is approximately five times that in the dry season. This clarifies that more significant river morphology changes occur during peak seasons. Further, the results of the study can be used in river dynamic process prediction, especially in alluvial streams or in soft soil with properties similar to that of alluvial streams.

In this paper, the differentiability on time and continuity on fractional order of solutions for a class of Caputo fractional evolution equations are studied. Under appropriate assumptions, the existence and differentiability on time of solutions for linear as well as semilinear Caputo fractional evolution equations are analyzed, the continuity of solutions on fractional order for linear and semilinear Caputo fractional evolution equations are discussed. In addition, if the fractional order converges to $1$, then the solutions of the Caputo fractional differential equations become the solutions of classic evolution equations. The continuity of solutions on fractional order for some fractional systems is numerically studied, and the results are basically consistent with the theoretical results.

Distributed order fractional differential equations are efficient in describing physical phenomena because of the differential order distribution. In this paper, the distributed order time-fractional reaction-diffusion equation is considered in the sense of Caputo fractional derivative. A hybrid method is developed based on the Moving Kriging (MK) interpolation and finite difference method for solving this distributed order equation. First, the distributed integral is discretized by the $M$-point Gauss Legendre quadrature rule. Then, the $L2-1_{\sigma}$ method is applied to approximate the solution of the fractional derivative discretization. Also, the unconditionally stability and rate of convergence $O(\tau^{2})$ of the time-discrete technique are illustrated. Furthermore, the MK interpolation is applied in the space variables discretization. Finally, some examples are presented to indicate the efficiency of this method and endorsement the theoretical results.

In this paper, Rational Bernstein polynomials on the semi-infinite interval are adapted to solve a Magnetohydrodynamic (MHD) problem. Also, the derivative, product, convert, and Galerkin Exact Operational Matrices (EOMs) of these polynomials are produced. Using the spectral Galerkin method and the Exact Operational Matrices (EOMs) of Rational Bernstein polynomials, we solve the problem with high accuracy and speed. The problem is the flow of MHD micropolar over a moving plate with suction and injection boundary conditions. Comparing the results of the Rational Bernstein Galerkin method with operational matrices and without operational matrices shows that the present method is faster than another method. Also, comparing the results of the Rational Bernstein Galerkin method and Rational Gegenbauer Tau method shows that the present method is more accurate than another method.

The most common pediatric extragonadal pelvic cancers include germ cell tumors, sacrococcygeal teratomas, and rhabdomyosarcomas (arising from the urinary bladder, prostate, paratesticular tissues, vagina, uterus, and perineum). This manuscript describes the radiological and nuclear medicine features of these entities and provides consensus-based recommendations for the assessment at diagnosis, during and after treatment.

Purpose: Pediatric patients with medulloblastoma in LMICs are most treated with 3D conformal photon craniospinal irradiation (CSI), a time-consuming, complex treatment to plan, especially in resource-constrained settings. Therefore, we developed and tested a 3D conformal CSI autoplanning tool for varying patient lengths. Methods and Materials: Autocontours were generated with a deep learning model trained:tested (80:20 ratio) on 143 pediatric medulloblastoma CT scans (patient ages, 2-19 years, median=7 years). Using the verified autocontours, the autoplanning tool generated 2 lateral brain fields matched to a single spine field, an extended single spine field, or 2 matched spine fields. Additional spine sub-fields were added to optimize the corresponding dose distribution. Feathering was implemented (yielding 9-12 fields) to give a composite plan. Each planning approach was tested on 6 patients (ages, 3-10 years). A pediatric radiation oncologist assessed clinical acceptability of each autoplan. Results: The autocontoured structures’ average Dice similarity coefficient ranged from 0.65-0.98. The average V95 for the brain/spinal canal for single, extended, and multi-field spine configurations was 99.9±0.06%/99.9±0.10%, 99.9±0.07%/99.4±0.30%, and 99.9±0.06%/99.4±0.40%, respectively. The average maximum dose across all field configurations to the brainstem, eyes (L/R), lenses (L/R) and spinal cord were 23.7±0.08 Gy, 24.1±0.28 Gy, 13.3±5.27 Gy, 25.5±0.34 Gy, respectively (prescription=23.4 Gy/13 fractions). Of the 18 plans tested, all were scored as clinically acceptable as-is or clinically acceptable with minor, time-efficient edits preferred or required. No plans were scored as clinically unacceptable. Conclusion: The autoplanning tool successfully generated pediatric CSI plans for varying patient lengths in 3.50 ± 0.4 minutes on average, indicating potential for an efficient planning aid in resource-constrained settings.

We present a case of epicardial pacemaker implantation in a low birth weight newborn using the Model 3830. We found that the Model 3830 implanted in the epicardium can obtain superior pacing parameters, but there is still need more evidence to support it.

Accelerated durability evaluation aims to quantify the fatigue damage of components in a shorter time. The quality of accelerated editing directly affects the evaluation's efficiency and accuracy. This paper proposes an accelerated spectrum editing method based on the multiaxial rainflow counting theory, then derives an equivalent fatigue damage model for the components. Take the steering knuckle of a passenger car as the research object, the fatigue damage caused by the original and the accelerated spectrums are evaluated by the proposed method. The evaluation results show that the proposed method has apparent advantages in compression efficiency, damage consistency, and retaining the frequency domain impact on the component. The research of this paper can provide a theoretical and practical reference for accelerated fatigue testing.

Diagnosing COVID-19 and treating its complications remains a challenge. This review reflects the perspective of some of the Dragon (IMI 2-call 21, #101005122) research consortium collaborators on the utility of bronchoalveolar lavage (BAL) in COVID-19. BAL has been proposed as a potentially useful diagnostic tool to increase COVID-19 diagnosis sensitivity. In both critically ill and non-critically ill COVID-19 patients, BAL has a relevant role in detecting other infections or in supporting alternative diagnosis, and can change management decisions in up to two-third of patients. BAL is used to guide steroid and immunosuppressive treatment and to narrow or discontinue antibiotic treatment reducing the use of unnecessary broad antibiotics. Moreover, cellular analysis and novel multi-omics techniques on BAL are of critical importance for the understanding of the microenvironment and interaction between epithelial cells and immunity revealing novel potential prognostic and therapeutic targets. The BAL technique has been described as safe for both patients and health care workers in more than a thousand procedures reported to date in the literature. Based on these preliminary studies, we recognize that BAL is a feasible procedure in COVID-19 known or suspected cases, useful to properly guide patient management and with great potential for research.

Indoxyl is an intermediate product in the production of indigo and indirubin. There are no studies on the inhibitory effect of indoxyl on microorganism. In this study, it was found that temperature-stress induced the synthesis of intracellular β-glucosidase, which had a great influence on the ratio of indican, indoxyl, indigo and indirubin in Strobilanthes cusia. At 100 ℃, only indican was detected, whereas a large amount of indoxyl was found at 50–70 ℃. HPLC analysis indicated that the use of indoxyl reduced glucose consumption and metabolite production by Staphylococcus aureus. The cells treated with indoxyl had irregular shapes, and fragments of cells were found in SEM images. The images of CLSM suggest that cell morphological changes would be caused by the inhibition of indoxyl on EMs formation. Moreover, indoxyl decreased intracellular ATP content and increased the NAD+/NADH ratio, which promoted the generation of H2O2, damaging cells.

IntroductionThe ironic phrase used by (Antoljak 2020) may be best to define the process of formation of BIM with reference to geotechnical engineering ‘the BIM collaboration is increasingly being achieved via data stored in and shared in the cloud. Geotechnical data that has always been so much down to earth now needs to be looked up in the cloud’. BIM allows governments and Architecture/Engineering/Construction organizations to collaborate and transform any infrastructure asset into a computer model long before breaking the ground. Consequently, many conflicts can be identified and resolved in the model at a fraction of the cost it would require to correct the mistake in the field (Antoljak 2020). As reported by (Tawelian and Mickovski 2016) geotechnical engineers fully support the integration of geotechnical data into the BIM process, while the majority of them consider that this would provide significant cost and time savings in major infrastructure projects. (Valeria, Roberta et al. 2019) Successfully imported a big quantity of borehole data in BIM software which were lately used for the design of soil nail reinforcements. (Berdigylyjov and Popa 2019) Investigated the barriers of integration of geotechnical and structural data as a single BIM model. It was stated that one of the obstacles was that many geotechnical engineers are discouraged from sharing data for the fear of possible interpretive misuse. (Fabozzi, Biancardo et al. 2021) performed a “3D BIM to finite element model (FEM) to BIM analysis” for a tunnel excavation case study. By the completion of the analysis the fourth dimension for project management was also added to the numerical model. It was shown that the existing 3D FEM software’s are not still mature enough for such complex systems and more improvement is necessary in this area. (Xu and Wang 2020) Used 3D geological modeling to conduct preliminary investigation of geotechnical survey results. (TUDublin and Brennan 2021) Conducted a case study on applying BIM for coastal infrastructure projects and proposed a potential of a 40 percent saving in capital budget. (Vaníček, Jirásko et al. 2021) State that by incorporation of BIM in geotechnical engineering along with 3D Geotechnical structure model, the necessary base for the future decision making would be created especially when some changes occur in the projects. (Goyal, Rai et al. 2022) Emphasized the revolutionary impact of BIM and transportation geotechnical engineering. (Bradley, Li et al. 2016) in a review highlighted the developing base of BIM for infrastructures from preliminary analysis to construction site and state that with the increasing complexity, Information uniqueness and governance requirements of infrastructure projects graph based technologies and distributed data environments are the way forward in meshing together and leveraging the vast amount of data produced by modern day architecture, engineering, construction, owner and operator Projects.Soils with poor geotechnical properties, such as weak clays, require improvement technique applications. Surcharge preloading along with PVDs is a very common technique nowadays and can be seen nearly in all section from urban to industrial industry, expanding to any location regardless of undesirable ground condition where it might be weak pits or expansive and sensitive marine clays. Since clays and peats have very low hydraulic conductivities, PVDs which have high hydraulic conductivity and high bending strength, are widely used in soft subsoil improvement. PVDs alter the drainage pass from vertical direction to horizontal, and accelerate the primary consolidation of soft ground. The basic concept of preloading is the reduction of weak soils void ratio through consolidation by applying pressure on ground surface for a predetermined time period and then removing whole or a part of embankment for construction of a permanent super structure. . A key design feature of prefabricated vertical drains (PVDs) use is to accelerate consolidation and increase shear strength of the weak, fine-grained foundation soil(Stark, Ricciardi et al. 2018) but care should be taken in real assessment of real behavior of the embankment. In the case of shortage of time, supplementary methods such as vacuum preloading might be applied as well. In such a case preloading consists of combined vacuum and surcharge preloading. Because of excessive downward and lateral forces, PVDs should be very flexible in nature otherwise the drainage capacity would be decreased or lost and in such a case differential settlement is unavoidable. In recent years new generations of PVDs with higher discharge capacity and strength were introduced like (Fu and Chai 2020, Zhang, Chen et al. 2020). Overestimation and false assumptions in design are the main factors which lead to embankment failures in most of the reported cases (Tan and Liew 2000, Hayashi, Nishimoto et al. 2011, Stark, Ricciardi et al. 2018).After preliminary site investigation and superstructure designation, based on project time schedule and cost, the soil treatment procedure is defined. Since such projects are often big-scale inherently, all parts from design to field executive operations are divided between different teams and smaller companies. Because of this inevitable division in responsibilities, there are always many clashes and inconsistencies between design offices and also between design sheets and field executive operations. This article discussed the importance of collaboration that should exist between structural and geotechnical designers and executive engineers. Two important items such as the infiltrated layer and the behavior of treated soil including PVDs in different phases of construction is discussed that is often neglected even in mega projects, and have the potential to become the reason for catastrophic failures in such projects.

M.M Pardsouie, Department of geotechnical engineering, Estahban Branch, Islamic Azad University, Estahban, Iran

This letter presents a novel structure of passive rectifier unit working in very high frequency (VHF) which could be used in implant devices in medical field or in sensor devices in internet of things (IoT) applications. The proposed rectifier utilized AC magnitude coupling adjustment technology which can effectively improve the PCE performance when the input voltage is high. Thus, the rectifier can hold high power convention efficiency (PCE) in a wide input range. The proposed AC magnitude coupling adjustment technology is based on tuning the capacitance, thus can adjust the coupled AC magnitude on the gate of the corresponding MOSFET. According to our simulation, the proposed rectifier structure can effectively improve the PCE performance when the input voltage is high, which can achieve a PCE higher than 60% in a wide input voltage range from about 0.8V to 3.3V.