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Device Performance of Emerging Photovoltaic Materials (Version 3)    
Osbel Almora

Osbel Almora

and 30 more

September 01, 2022
Osbel Almora*, Derya Baran, Guillermo C. Bazan, Carlos I. Cabrera, Kylie R. Catchpole, Sule Erten-Ela, Karen Forberich, Fei Guo, Jens Hauch, Anita W.Y. Ho-Baillie, T. Jesper Jacobsson, Rene A.J. Janssen, Thomas Kirchartz, Nikos Kopidakis, Yongfang Li, Maria A. Loi, Richard R. Lunt, Xavier Mathew, Michael D. McGehee, Jie Min, David B. Mitzi, Mohammad K. Nazeeruddin, Jenny Nelson, Ana F. Nogueira, Ulrich W. Paetzold, Nam-Gyu Park, Barry P. Rand, Uwe Rau, Henry J. Snaith, Eva Unger, Lídice Vaillant-Roca, Hin-Lap Yip, and Christoph J. Brabec*Dr. O. AlmoraUniversity Pablo de Olavide, Seville, SpainDr. O. Almora, Prof. C. J. BrabecErlangen Graduate School of Advanced Optical Technologies (SAOT), 91052 Erlangen, Germany.Prof. D. BaranKing Abdullah University of Science and Technology (KAUST), Division of Physical Sciences and Engineering (PSE), KAUST Solar Center (KSC), Thuwal 23955, Saudi Arabia.Prof. G.C. BazanDepartments of Chemistry and Chemical Engineering, National University of Singapore, SingaporeProf. C.J. BrabecZernike Institute for Advanced Materials University of Groningen Groningen 9747, The NetherlandsDr. C.I. CabreraUnidad Académica de Ciencia y Tecnología de la Luz y la Materia, Universidad Autónoma de Zacatecas, Zacatecas, 98160, MexicoProf. K.R. CatchpoleResearch School of Electrical, Energy and Materials Engineering, The Australian National University, Canberra 2601, AustraliaProf. S. Erten-ElaEge University, Solar Energy Institute, Bornova, 35100, Izmir, TurkeyProf. F. GuoInstitute of New Energy Technology, College of Information Science and Technology, Jinan University, Guangzhou 510632, ChinaProf. C.J. Brabec, Dr. Karen Forberich, Dr. J. Hauch, Dr. C. BergerForschungszentrum Jülich GmbH, Helmholtz‐Institut Erlangen‐Nürnberg for Renewable Energy (HI ERN), 91058 Erlangen, GermanyProf. A.W.Y. Ho-BaillieSchool of Physics and The University of Sydney Nano Institute, The University of Sydney, NSW 2006, AustraliaDr. T.J. JacobssonInstitute of Photoelectronic Thin Film Devices and Technology, Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin, College of Electronic Information and Optical Engineering, Nankai University, Tianjin 300350, ChinaDr. E. UngerHySPRINT Innovation Lab (Young Investigator Group Hybrid Materials Formation and Scaling), Helmholtz Zentrum Berlin, Kekuléstrasse 5, 12489 Berlin, GermanyProf. R.A.J. JanssenMolecular Materials and Nanosystems & Institute for Complex Molecular Systems, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands; Dutch Institute for Fundamental Energy Research, De Zaale 20, Eindhoven, 5612 AJ, The NetherlandsProf. T. Kirchartz, Prof. U. Rau,IEK5-Photovoltaics, Forschungszentrum Jülich, 52425 Jülich, GermanyProf. T. KirchartzFaculty of Engineering and CENIDE, University of Duisburg-Essen, 47057 Duisburg, GermanyDr. N. KopidakisPV Cell and Module Performance group, National Renewable Energy Laboratory (NREL), 15313 Denver West Parkway, United StatesProf. Y. LiSchool of Chemical Science, University of Chinese Academy of Sciences, Beijing 100049, China; Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, ChinaProf. M.A. LoiPhotophysics and OptoElectronics Group, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, NL-9747 AG Groningen, The NetherlandsProf. R.R. LuntDepartment of Chemical Engineering and Materials Science, Department of Physics and Astronomy, Michigan State University, East Lansing, Michigan 48824, United StatesProf. X. MathewInstituto de Energías Renovables, Universidad Nacional Autónoma de México, Temixco, Morelos 62580, MéxicoProf. M.D. McGeheeDepartment of Chemical and Biological Engineering & Materials Science and Engineering Program, University of Colorado, Boulder, Colorado 80309, United States; National Renewable Energy Laboratory, 15013 Denver West Parkway, Golden, Colorado 80401, United StatesProf. Dr. J. MinThe Institute for Advanced Studies, Wuhan University, Wuhan, 430072, China; Key Laboratory of Materials Processing and Mold (Zhengzhou University), Ministry of Education, Zhengzhou, 450002 ChinaProf. D.B. MitziDepartment of Mechanical Engineering and Material Science & Department of Chemistry, Duke University, Durham, North Carolina 27708, United StatesProf. M. K. NazeeruddinGroup for Molecular Engineering and Functional Materials, Ecole Polytechnique Fédérale de Lausanne, Institut des Sciences et Ingénierie Chimiques, CH-1951 Sion, SwitzerlandProf. J. NelsonDepartment of Physics, Imperial College London, London SW7 2BZ, UKProf. A.F. NogueiraChemistry Institute, University of Campinas, PO Box 6154, 13083-9 70, Campinas, São Paulo, BrazilDr. U.W. PaetzoldInstitute of Microstructure Technology (IMT), Karlsruhe Institute of Technology (KIT), 76344, Eggenstein-Leopoldshafen, Germany; Light Technology Institute (LTI), Karlsruhe Institute of Technology (KIT), 76131, Karlsruhe, GermanyProf. N.-G. ParkSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Korea.Prof. B.P. RandDepartment of Electrical Engineering and Andlinger Center for Energy and the Environment, Princeton University, Princeton, New Jersey 08544, United StatesProf. H. J. SnaithClarendon Laboratory, Department of Physics, University of Oxford, Oxford OX1 3PU, UK.Prof. L. Vaillant-RocaPhotovoltaic Research Laboratory, Institute of Materials Science and Technology – Physics Faculty, University of Havana 10400, Havana, CubaProf. H.-L. YipDepartment of Materials Science and Engineering and Hong Kong Institute for Clean Energy, City University of Hong Kong, Tat Chee Avenue, Kowloon 999077, Hong Kong*osbel.almora@fau.de,
p-ADIC WELCH BOUNDS AND p-ADIC ZAUNER CONJECTURE
K. Mahesh Krishna

K. Mahesh Krishna

September 01, 2022
Let p be a prime. For d ∈ N, let Q d p be the standard d-dimensional p-adic Hilbert space. Let m ∈ N and Sym m (Q d p) be the p-adic Hilbert space of symmetric m-tensors. We prove the following result. Let {τ j } n j=1 be a collection in Q d p satisfying (i) τ j , τ j = 1 for all 1 ≤ j ≤ n and (ii) there exists b ∈ Q p satisfying [ n j=1 x, τ j τ j = bx for all x ∈ Q d p. Then max 1≤j,k≤n,j =k {|n|, ||τ j , τ k | 2m } ≥ |n| 2 d+m−1 m. (1) We call Inequality (1) as the p-adic version of Welch bounds obtained by Welch [IEEE Transactions on Information Theory, 1974 ]. Inequality (1) differs from the non-Archimedean Welch bound obtained recently by M. Krishna as one can not derive one from another. We formulate p-adic Zauner conjecture.
No phase transition for SU(2) black holes
Wen-Xiang Chen

Wen-Xiang Chen

and 1 more

September 01, 2022
In this article, we fabricate a black hole metric that conforms to the SU(2) group structure and compute the scalar curvature of the thermodynamic geometry of this black hole. We conclude that there is no phase transition for SU(2) black holes.
A New Multilevel Inverter Topology for Symmetrical and Asymmetrical Configuration
kalidindi satya surya prasad raju
Kanchapogu Vaisakh

kalidindi satya surya prasad raju

and 1 more

August 31, 2022
This paper presented a new modular symmetrical and asymmetrical multilevel inverter topology. The multilevel output is obtained either with independent DC source or additive or subtractive combination with other DC sources. This paper presents a new algorithm ( an alternative quinary sequence) for choosing input dc voltage sources magnitude. Switching pulses to the proposed topology is created using Phase Opposition Disposition (POD) pulse width modulation technique. The proposed topology shows better performance compared to a few recent topologies in terms of the switches count, DC sources count and the cost function. Switching states were derived for the proposed topology to create 5-Level, 9-Level and 49-Level. Simulation and experimental results verify the validity of the proposed topology. Prototype was developed to generate 9-Levels in the output voltage.
Potential Mechanisms for Human Genome Integration of Genetic Code from SARS-CoV-2 mRN...

Anthony M Kyriakopoulos

and 3 more

September 01, 2022
Background The findings of a sequence embedded in Human DNA that was almost identical to a sequence in the SARS-CoV-2 genome, and the identification of plausible integration of SARS-CoV-2 RNA into human DNA by endogenous reverse transcriptase activity expressed by Long Interspersed Nuclear Element (LINE)-1 (17% of Human DNA) have raised concerns about the long-term safety of messenger-RNA (mRNA) based vaccination. Recent data demonstrate that SARS-CoV-2 RNA sequences can be transcribed into DNA and may be actively integrated into the genome of affected human cells, mediated by retrotransposons. Complementarily, in some SARS-CoV-2 infected patient specimens, there is evidence for a large fraction SARS-CoV-2 sequence integration and subsequent generation of SARS-CoV-2-human chimeric transcripts. 2 Results In this review, the potential role of mobile genetic elements in the etiopathogenesis of cardiovascular, neurological, immunological, and oncological disease and the possibilities of human DNA interference by SARS-CoV-2 vaccination are repositioned. Vulnerable human stem cells as well as gametocytes can presumably be the first targets for unwanted RNA interference. Given the many genetic manipulations of the RNA coding for the SARS-CoV-2 spike glycoprotein in the vaccines, manipulations designed to increase stability and efficiency of spike protein translation, much remains uncertain about the potential disruptions to cellular physiology and homeostasis that could ensue. The predicted consequences pose serious risks to human health that are in need of clarification. Conclusion Further toxicity evaluations are urgently needed to quantify potential emergence of interference with canonical DNA processes that could detrimentally impact the mRNA-vaccinated population.
Trend of the Application of Hybrid Artificial Neural Network Models in Bioprocesses
Roshanak Agharafeie
Rui Oliveira

Roshanak Agharafeie

and 2 more

August 30, 2022
Due to the complexity of biological transformations, developing model-based strategies to optimize and control bioprocesses is nontrivial. Hybrid models combining a mechanistic description of known influential factors with machine learning to infer the missing influential factors from data have been reported as powerful tools for bioprocesses applications. The artificial neural network is one of the most popular machine learning methods in this case. This paper presents a systematic literature review by computerized search across two databases: Scopus and Web of Science, and backward citation. The PRISMA method was applied to selecting the publications and 159 research articles were categorized as hybrid model applications to bioprocesses problems. It was found that hybrid models were mainly applied in upstream operation steps with a predominance of bioreaction steps. In downstream processing, chromatography appeared as a more recent research topic, with a relatively small number of publications. Furthermore, holistic hybrid modeling applications that integrate data and knowledge from several bioprocess steps will likely emerge in the future, enabling better optimization and control of the bioprocess’s platform. The combination of other machine learning methods with the hybrid neural network model is another opportunity that could improve the output of the model.
 Inter-Specific Hybridization in Cotton (Gossypium hirsutum) for Crop Improvement    
Muhammad Zafar Iqbal

Muhammad Zafar Iqbal

September 01, 2022
ReviewInter-Specific Hybridization in Cotton (Gossypium hirsutum ) for Crop ImprovementMuhammad Zafar Iqbal 1, * Muhammad Anwar2
Industrial hazards and safety management in pharmaceutical industry
Shmmon Ahmad

Shmmon Ahmad

and 6 more

September 01, 2022
Hazard is a term associated with a substance that is likely to cause an injury in a given environment or situation. Industrial hazards are major occupational health and safety (OHS) issue in Pharmaceutical manufacturing. In recent years chemical safety and the sound management of chemicals have seen great progress at the global level. At the same time, the rapid growth in production and dissemination of both natural and synthetic chemicals has led to concern about their impact on the natural environment, and human health. In this way, the pharmaceutical industry has come to occupy a unique position. Practically no other commercial enterprises present such as a wide variety of potentially toxic exposures or such a rapidly changing advent of new chemical substances. In the pharmaceutical industry, this dynamic situation has been created by the increasing application of organic chemical synthesis as a technique for producing therapeutic substances. This renders the work of the plant physician so instructive. Industrial safety is needed to check all the possible chances of accidents for preventing loss of life and permanent disability of any industrial worker, any damage to machine and material leads to the loss of the whole establishment.
Importance of data integrity & its regulation in pharmaceutical industry
Shmmon Ahmad

Shmmon Ahmad

and 2 more

September 08, 2022
Data integrity is an important current issue for regulators around the world. During inspections a multitude of problems being found by the pharmaceutical regulatory agency because poor practices develop the substandard product for patients. Collection of various types of information and results collectively made in the form of data. This data becomes one of the most valuable assets of any organization but without integrity, this data is not much useful. Accuracy and original data increase the chances of stability and performance of an organization.
POLYMORPHISM AND SOLID STATE TRANSITION OF ANTIHYPERLIPIDEMIC DRUG SIMVASTATIN: PREPR...
Shmmon Ahmad

Shmmon Ahmad

and 1 more

September 11, 2022
Recently it has been growing interest in investing solid state transition forms prepared by different technique. The majority of drugs are administered in solids form. Among all newly discovered chemical entities about 40% drugs are lipophillic and fail to reach market due to their poor aqueous solubility. Problem of solubility is a major challenge for formulation scientist, which can be resolved by different technological approaches. Simvastatin belong to class of antihyperlipidemic drugs having very low solubility and falls in category II Class of BCS. Polymorphism and solid state transitions change the solid-state property which is significantly influence the performance of the final product such as solubility, Melting Point, Dissolution Rate and flow property. Optimization process like RCM and CCD design was used to study the effect of variables such as solubility and melting point for quality determination of formulation. Solvent evaporation method is used in this study to prepare new transition form. This technique has more advantages and it is preferred method over others such as spray drying, sonication and homogenization. Through the characterized analysis (SEM, XRD, ATR, DSC, Solublity and melting point) of optimised form, given reliably confirmation data that the new solid state transition forms is amorphous form. It is more soluble than crystalline form.
Application of specific Bacteriophages against prevention of Staphylococcus aureus to...
Shmmon Ahmad

Shmmon Ahmad

and 5 more

September 27, 2022
Samples taken from pond water (Padila), river ganga water (Sangam, Allahabad) sewage water (Yamuna drainage) supply water from Municipal Corporation (Daraganj) were found that Ganga water (Sangam) has positive (large, small, medium) plaque formation other pond water, sewage water, supply water from municipal Corporation do not have plaque formation. It can be predict that Ganga water has high presence of S. aureus plaque formation for bacteriophages. Help in therapeutic process, drug target discovery, bacteriophages isolate from environment or Ganga water sample to specifically target pathogenic bacteria and eliminate them from foods. Bacteriophages approved or use in food safety application, genetically engineered phages to specifically target bacterial virulence-associated genes, control multidrug resistant S. aureus, implications in biofilm treatment, the progress in the knowledge about phage genomics, immunobiology and experimental therapy in animals and in humans suggest that phages could become the antibacterial drugs of the 21st century.
Title: Philosophiae Naturalis Principia Mathematica

Isaac Newton

September 01, 2022
Isaac Newton, Philosophiæ Naturalis Principia retypeset via LaTeX by Project Gutenberg
The Outbreak Of Human Monkeypox Amidst Covid-19 Delta Variant: Suspicion Of A Possibl...
Ibad ur  Rehman
Dr Khadija  iqbal

Ibad ur Rehman

and 3 more

August 30, 2022
The Human Monkeypox virus belongs to the Poxvirdiae family of the Orthopoxvirus genus. This virus is seen to get transmitted to humans predominantly by contact transmission via infected animals and humans. It exhibits a range of clinical features apart from the common rash, swollen lymph nodes, and flu-like symptoms.
A tale about an unusual cause of pygalgia in ankylosing spondyloarthritis
Rim Dhahri
Bettaieb Hiba

Rim Dhahri

and 9 more

August 30, 2022
Neurinomas are tumors of Schwann cells of the peripheral nerve sheath. Sacral location is rarely reported especially in spondyloarthritis patients. Herein, we report a case of uncommon pygalgia in a 25-year-old man with history of a non-radiographic axial spondyloarthritis and in whom the diagnosis of sacral neurinoma was established.
ACUTE DYSPHAGIA: AN UNUSUAL CAUSE
Angelica Tobon
Fredy Avila

Angelica Tobon

and 1 more

August 30, 2022
Anterior cervical spine surgery with placement of osteosynthesis material is common in cervical trauma. The following is the case of a 52-year-old with progressive dysphagia and endoscopic examination incidentally evidenced a plate anterior metal in the posterior aspect of the hypopharynx.
Mini-commentary on “Familial aggregation of stillbirth: a pedigree analysis of a matc...
Matthew Shear

Matthew Shear

August 30, 2022
JOURNAL: BJOGDATE 08_25_2022TITLE: Mini commentary on “Familial aggregation of stillbirth: a pedigree analysis of a matched case control study” BJOG_22-0217Author: Matthew A. Shear, MDa,bAuthor Affiliations:a Department of Obstetrics, Gynecology, & Reproductive Sciences, University of California, San Franciscob Division of Medical Genetics, Department of Pediatrics, University of California, San FranciscoDespite advances in genomics, the underlying cause of many stillbirths remains elusive. The emotional toll that a stillbirth takes on families, as well as the providers caring for them, is hard to overstate. Karyotype may identify a causative aneuploidy or large unbalanced translocation, but only in about 6% of stillbirths. Chromosomal microarray is higher yield, but still only identifies pathogenic copy number variants in about 10% of stillbirth cases (Reddy et al. N Engl J Med. 2012). The addition of exome sequencing to microarray only yielded a plausible genetic explanation in 15 out of 246 cases, or about 6% (Stanley et al. N Engl J Med. 2020). This suggested that non-mendelian mechanisms may play a significant role in stillbirth (Wojcik et al N. Engl J Med. 2020), although single gene pathogenic variants are poorly understood at the fetal level relative to the postnatal setting. The non-genetic mechanisms underlying stillbirth are also poorly understood at present, including viral infections, environmental toxins, and comorbid conditions.Workalemahu and their colleagues present a unique analysis suggesting genomic heritability of stillbirth in some families. Using a robust matched case-control study of over 9000 stillbirths and 390 high-risk pedigrees from the Utah Population Database, they calculated the familial standardized incidence ratio and risk of stillbirth among first, second, and third-degree relatives of the pregnant individuals who had experienced stillbirth. In their adjusted model, among all relatives of an individual who experienced stillbirth, there was a relative risk of stillbirth of 1.1 (95% CI 1.00-1.22). This study adds further evidence there are heritable genetic etiologies of stillbirth not yet fully described.Many non-genetic contributors to stillbirth risk may also cluster in families. In the present study, when adjusting for maternal race/ethnicity, socioeconomic status, and education, the elevations in stillbirth risk became attenuated, although this may be due to collinearity among variables used in the model. Health behaviors are informed through regional and family culture, leading to patterns in diet, nutrition, and exercise. These patterns contribute to modifiable health conditions known to impact stillbirth risk, including hypertension, obesity, diabetes, and smoking status. We also know the incidence of stillbirth is higher in lower income versus higher income countries, higher among individuals of lower educational attainment versus higher education, and higher among African American and Black individuals compared to White, likely complicated by the impacts of systemic racism. This is to say nothing of the additional social determinants of health that may impact families across generations.As Workalemahu and colleagues note, there is still much unknown about complex outcomes such as stillbirth. Their findings support that for a patient with a high-risk pedigree, genomic testing may prove informative. Future epigenetic and functional studies may help understand variants at the tissue level, and the impact of comorbidities on gene expression. Together with fetal genome sequencing, previously unexplained cases of stillbirth might be solved, improving patient counseling, and possibly changing clinical management. While genomic testing offers promise to explain a subset of stillbirths, we should not neglect the “non-mendelian” and non-genetic factors that continue to play a significant role in stillbirth risk.
Implementing Effective Investigations for Cause of Stillbirth
Elizabeth McClure
Robert L Goldenberg

Elizabeth McClure

and 1 more

August 30, 2022
BJOG-22-0382.R1: Implementing Effective Investigations for Cause of StillbirthElizabeth M McClure, PhDRobert L Goldenberg, MDRTI International, Durham, NCColumbia University, New York, NYStillbirth is one of the most common adverse pregnancy outcomes in low and middle-income countries (LMICs), with rates in the range of 40 to 50 per thousand births in some regions [1]. International goals aim for no country to have a rate of >10 per thousand births by 2035 [Hug L, et al. Lancet. 2021;398(10302):772-85]. To achieve this, a better understanding of stillbirth causes often requiring additional investigations is critical. For several reasons, including low prioritization, inadequate resources, and hesitancy by families and providers, investigations on stillbirth causes in LMICs have been limited to date.Bedwell et al used a grounded theory approach to explore the views of women, partners, families, health workers and community leaders in Malawi, Tanzania, and Zambia regarding investigations to determine the cause(s) of stillbirth [Bedwell et al, BJOG (in press)]. While most would like more information regarding the stillbirth, the authors noted cultural and religious obstacles to performing the investigations, including preferences for quick burial, reluctance to disfigure the deceased fetus, concerns about blame, as well as costs.One test to inform cause of stillbirths is minimally invasive tissue sampling (MITS), using needle biopsies to obtain internal organ tissue for histological evaluation and microbial analyses. For a study on causes of stillbirth in Pakistan and India, we explored the acceptability of MITS among parents, relatives, religious leaders, and government officials [Feroz A, et al. Reprod Health.2019;16(1):53]. The perceived benefits included knowing the cause of death, and both personal and societal benefits in preventing subsequent stillbirths. Concerns regarded rapid burial and reluctance to disfigure the stillborn. In Pakistan, with some caveats, religious leaders approved, and, when MITS was undertaken, in both Pakistan and India, approximately 50% of the parents consented for the MITS procedure.Because obstacles to testing in general and to MITS specifically relate to time, cost, and disfigurement, we have considered which examinations feasible in LMICs provide the most information at minimal cost. Page et al., in a similar exercise in a US study, noted that the most useful test was placental histology (65%) followed by full autopsy (42%) [Page JM, Obstet Gynecol 2017;129(4):699-706.]. No other tests were useful for >12% of cases. Similar studies have rarely been performed in LMICs. The prevalence of the causes relates to the frequency of tests’ usefulness. In high-income countries where birth asphyxia and infection have been reduced, congenital and genetic anomalies have assumed a larger proportion of stillbirths, and testing for those conditions using karyotyping and other genetic tests become proportionately more important. However, in many LMICs, birth asphyxia remains the major cause of stillbirth and genetic issues play a smaller proportional role.To develop the most effective methodology to determine cause of stillbirth, the prevalent conditions, and the tests’ usefulness to diagnose those conditions should be considered together. Importantly, the community and other stakeholder’s perceived benefits and obstacles to various tests as described in the Bedwell, et al must be considered to ultimately be successful in implementing the necessary investigations.For LMICs, given that asphyxia and infection appear to be major causes of stillbirth, tests to diagnose these conditions will likely be important to implement, including the obstetric history and histological placental evaluation for diagnosing asphyxia and infection. Of potential information gained from MITS, histology of the fetal lung, and bacteriological assessment of the fetal blood and brain/CSF may be the most useful. Thus, by considering the prevalence of the causes of stillbirth, the usefulness of tests to diagnose the prevalent conditions, and importantly addressing the community’s sense of benefit and obstacles, an effective approach to stillbirth cause of death investigation can be developed.Declaration of Interest: The authors declare no conflicts of interest.
Comparative Effectiveness and Safety of Direct Oral Anticoagulants versus Warfarin in...
Sylvie Perreault
Laurie-Anne Boivin-Proulx

Sylvie Perreault

and 4 more

August 30, 2022
Aim: The effectiveness and safety of direct oral anticoagulants (DOACs) in atrial fibrillation (AF) patients with stage III chronic kidney disease (CKD) are still subject to debate. We therefore assessed and compared the effectiveness and safety of DOACs vs. warfarin in this population. Methods: A cohort of patients with an inpatient or outpatient code for AF and stage III CKD who were newly prescribed an oral anticoagulant (OAC) was created using administrative databases from the Quebec province of Canada between 2013 and 2017. The primary effectiveness outcome was a composite of ischemic stroke, systemic embolism, and death, whereas the primary safety outcome was a composite of major bleeding within a year of DOAC vs. warfarin initiation. Treatment groups were compared in an on-treatment analysis using inverse probability of treatment weighting and Cox proportional hazards. Results. A total of 8,899 included patients filled a new OAC claim: 3,335 for warfarin and 5,564 DOACs. Compared with warfarin, rivaroxaban 15 mg and 20 mg presented a similar effectiveness and safety composite risk. Apixaban 5.0 mg was associated with a lower effectiveness composite risk (Hazard ratio [HR] 0.76; 95% confidence interval [CI] 0.65–0.88) and a similar safety risk (HR 0.94; 95% CI 0.66–1.35), whereas apixaban 2.5 mg was associated with a similar effectiveness composite (HR 1.00; 95% CI 0.79–1.26) and a lower safety risk (HR 0.65; 95% CI 0.43–0.99). Conclusion: In comparison with warfarin, rivaroxaban and apixaban appear to be effective and safe in AF patients with stage III CKD.
Surface modified iron-oxide based engineered nanomaterials for hyperthermia therapy...
Mehak Dhiman

Mehak Dhiman

August 30, 2022
Surface modified iron-oxide based engineered nanomaterials for hyperthermia therapy of cancer cellsMehak1, Rajkumar P Thummer2, Lalit M. Pandey1*1Bio-interface & Environmental Engineering LabDepartment of Biosciences and Bioengineering,Indian Institute of Technology Guwahati, Assam, 781039, India2Laboratory for Stem Cell Engineering and Regenerative MedicineDepartment of Biosciences and Bioengineering,Indian Institute of Technology Guwahati, Assam, 781039, India* Corresponding author: Tel. +91-361-258-3201; Fax +91-361-258-2249Email addresses: mehak1998@iitg.ac.in, rthu@iitg.ac.in, lalitpandey@iitg.ac.in
Designing Economic Evaluations Alongside Clinical Trials in Maternal Healthcare: A Pr...
Emily Callander
Hema Mistry

Emily Callander

and 2 more

August 30, 2022
Economic evaluations are increasing being conducted in the maternity setting, with many randomised controlled trials conducted with a health economic component. A key criticism of economic evaluation in maternity care is a lack of robust data collection and measurement, inconsistencies in methodology and lack of adherence to reporting guidelines. This article provides a guide to the design of economic evaluations alongside clinical trials in maternal health. We cover economic concepts and considerations for the maternity setting and provide examples from the United Kingdom and Australia. We seek to improve the quality, consistency, and transparency of economic evaluations in maternal health.
The Advent Of Imam Mahdi As The Avenger Of Imam Hussein
Reza Rezaie Khanghah

Reza Rezaie Khanghah

August 30, 2022
Purpose: This article attempts to deal with the events that took place during the advent (reappearance) of Imam Mahdi, the Savior of all the worlds. In fact, in this article, we will discuss the forces that will join him when the Imam of the time appears, and above all, with Imam Hussein and how globalization can pave the way for Imam Mahdi's world revolution. Also, this research was conducted to answer and clarify three questions that stated in the Introduction section. Methods: We performed our methods in 4 stages: Identifying studies, Selection of Studies, Collating Studies, Reporting results. Results: One of the reasons why the Imam of the Age (Imam Mahdi) rises is because of the killing of Imam Hussein, and God has made a firm promise that he will take revenge on any of the perpetrators who led this incident by Imam Mahdi. Imam Hussein also states that the basis of his rising was inviting people to the Quran and the Prophet's Sunnah. Conclusion: God helps Imam Mahdi and Jesus Christ to establish divine government on earth, and this is accepted by Muslims and Christians. Dread and terror, as part of Imam Mahdi's power, will move in advance of his soldiers. Imam Mahdi will appear with the aim of reforming humanity and spreading justice in the world. We hope this article will take an important step in acquainting people with Imam Mahdi and Jesus Christ and paving the ground for their reappearance.
Imam Mahdi, Antichrist Or A Promised Saviour Besides Jesus Christ?
Reza Rezaie Khanghah

Reza Rezaie Khanghah

September 01, 2022
A document by Reza Rezaie Khanghah. Click on the document to view its contents.
Who Is Imam Mahdi, Prophesied In Other Religions, And From Holy Fatima lineage?
Reza Rezaie Khanghah

Reza Rezaie Khanghah

August 30, 2022
Purpose: In this article, we will discuss the narrations and prophecies that exist in Islam, both in Shia, Sunni and other religions regarding Imam Mahdi. This article also attempts to deal with Holy Fatima and her characteristics. Also, we will show that Imam Mahdi is mentioned not only in other religions but also in other books. Also, this research was conducted to answer and clarify three questions that stated in the Introduction section. Methods: We performed our methods in 4 stages: Identifying studies, Selection of Studies, Collating Studies, Reporting results. Results: According to Abrahamic religions, a person will reappear and establish fairness and justice with the help of God, who is called Imam Mahdi and based on the opinion of Christians, he is Christ. If the Shiites, may Allah help them in His obedience, had fulfilled their covenant with united hearts, then there would have been no delay in meeting the Promised Saviour. Conclusion: The concept of Imam Mahdi is universal and cannot just be rejected. The appearance of Imam Mahdi will coincide with the coming back of Jesus Christ. Imam Mahdi, with the assistance of the Messiah, will ensure the completion and practical actualization of the mission of the Prophet Muhammad. The Hidden Imam wrote to Abu-Omar Ameri: The Prophet’s daughter (Holy Fatima) is a nice model for me. We hope this article will take an important step in acquainting people with Imam Mahdi and Jesus Christ and paving the ground for their reappearance.
Imam Mahdi And Jesus Christ Role In Establishing The Divine Government
Reza Rezaie Khanghah

Reza Rezaie Khanghah

August 30, 2022
Purpose: This article covers the events and incidents predicted before and after the appearance of Imam Mahdi and Jesus Christ. This article seeks to address the facts and inform you about the system of government of Imam Mahdi and Jesus Christ. Also, miracles and the titles of Imam Mahdi are other topics that were mentioned in this article. Also, this research was conducted to answer and clarify three questions that stated in the Introduction section. Methods: We performed our methods in 4 stages: Identifying studies, Selection of Studies, Collating Studies, Reporting results. Results: Imam Mahdi's world government follows the pattern of the Prophet's method of rule in early Islam. Jesus Christ has a special status in the Quranic literature and in the hadith, and plays a special role in establishing the divine government with Imam Mahdi. Imam Mahdi's system of government is unlike any government the world has ever known. Conclusion: Among the issues that exist in the apocalypse, we are faced with an issue called Imam Mahdi. In fact, Imam Mahdi is the savior of Muslims and all people with Jesus Christ. Imam Mahdi will form a just government in the world like his ancestors. We hope this article will take an important step in acquainting people with Imam Mahdi and Jesus Christ and paving the ground for their reappearance.
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