AbstractToxic Epidermal Necrolysis (TEN) is an acute, uncommon, extensive, and life-threatening dermatological condition, which is caused by a delayed adverse response of the skin to a particular type of drug. Herein, we report a 41-year-old female with a known case of IgA nephropathy admitted for having TEN after a recent intake of Deflazacort, developed systemic candidiasis during admission, and was successfully treated with oral fluconazole. Early detection and immediate antifungal treatment of invasive candidiasis in TEN are crucial to prevent systemic complications and enhance patient outcomes.

Although the presence of morphea following COVID-19 has been rarely reported, development of its generalized form following COVID-19 vaccination has not been reported yet. Here, we reported the first case of generalized morphea following COVID-19 vaccination and another similar case following SARS-Cov-2 infection. Other etiologic factors were also dealt with

here we report a case of cutaneous Pseudolymphoma progression to frank cutaneous lymphoma and resistant to conventional therapy after receiving Platelet-rich plasma and hair transplantation .these modalities and their proliferative formulation may be the leading cause or aggravating factor for such transformation's specially for patients with positive family history,