Tuberculosis(TB) is a common disease in Sudan .Neurological consequences of TB are frequently encountered in our practice of neurology particularly tuberculosis of the spine(Pott,s disease).There are few case reports of tuberculous myelitis in literature.

Background: Many studies done during this pandemic revealed several neurological manifestations related to coronavirus disease 2019 or COVID 19 infection. The aim of this narrative review is to discuss the neurological manifestations and complications of COVID-19 disease. Methods: Data were retrieved from: PubMed, Scopus, Science direct in addition to manual search using Google scholar from December 2019–May 2020.Keywords were used in the search such as COVID-19; Neurological manifestations; Cranial nerves; Motor system. Results: Neurological manifestations and complications are common and increase with the severity of the respiratory involvement . It ranges from 34% to reach 80% in some studies. It involves the central and peripheral nervous system leading to cranial nerves palsies and limbs paralysis. Conclusion: Neurological complications of COVID-19 is an important determinant for the severity and mortality of patients .The virus can lead to Headache, Convulsion, Mental and Psychic changes , Delirium and Insomnia (the most affected cranial nerve is the olfactory nerve leading to anosmia), Stroke (mainly infarction), Encephalitis, Meningitis , Guillain-Barre Syndrome ,Relapse of Multiple Sclerosis and Transverse Myelitis.

Human African Trypanosomiasis also known as sleeping sickness is a common disease in South Sudan. There are two recognized sstage, The early hemolymphatic stage and The late encephalitic stage when the CNS is involved specially with Gambians infection, broad neurologic spectrum has been reported such as psychiatric, motor, sensory.

Neurological manifestation and complications are common due to COVID-19. It affects higher functions, cranial nerves and the motor system. The authors report a case of GBS as an example of a success story in managing a complicated case of COVID-19 in an elderly male with signs of a poor prognosis.