This paper studies the non-autonomous non-Newtonian micropolar fluids in two-dimensional bounded domains. We first establish that the generated continuous process of the solutions operator possesses a pullback attractor. Then we verify the existence of statistical solutions by constructing the invariant Borel probability measures. Further, we prove that the statistical solutions possess the degenerated regularity of Lusin's type provided that the Grasshof number associated to the external forces is small enough.

Primary repair was carried out in a neonate with an atypical form of double outlet right ventricle; with a non-committed ventricular septal defect and lack of the outlet septum between the semilunar valves. The aortic arch was right-sided. The procedure required a right ventricular incision. Intraventricular rerouting could be achieved concomitantly with the arterial switch maneuver. Retrospectively, several strategies were contemplated to seek whether any other approach could have been superior to our present choice.

In this paper, we study the stabilization of a coupled wave system formed by one localized non-regular fractional viscoelastic damping of Kelvin-Voigt type and localized non-smooth coefficients. Our main aim is to prove that the C0-semigroup associated with this model is strong stability and decays polynomially at a rate of t−1. By introducing a new system to deal with fractional Kelvin-Voigt damping, we obtain a new equivalent augmented system, so as to show the well-posedness of the system based on Lumer-Phillips theorem. We achieve the strong stability for the C0-semigroup associated with this new model by using a general criteria of Arendt-Batty, and then turn out a polynomial energy decay rate of order t−1 with the help of a frequency domain approach.

The selection of layers in the transfer learning fine-tuning process ensures a pre-trained model’s accuracy and adaptation in a new target domain. However, the selection process is still manual and without clearly defined criteria. If the wrong layers in a neural network are selected and used, it could lead to poor accuracy and model generalisation in the target domain. This paper introduces the use of Kullback-Leibler divergence on the weight correlations of the model’s convolutional neural network layers. The approach identifies the positive and negative weights in the ImageNet initial weights selecting the best-suited layers of the network depending on the correlation divergence. We experiment on four publicly available datasets and four ImageNet pre-trained models that have been used in past studies for results comparisons. This proposed approach method yields better accuracies than the standard fine-tuning baselines with a margin accuracy rate of 10.8% to 24%, thereby leading to better model adaptation for target transfer learning tasks.

{In the present paper, a $\mu$-delayed Mittag-Leffler type function is introduced as a fundamental function. By means of $\mu$-delayed Mittag-Leffler type function, an exact analytical solution formula to non-homogeneous linear delayed Langevin equations involving two distinct $\mu$-Caputo type fractional derivatives of general orders is given. Also, a global solution of nonlinear version of delayed Langevin equations is inferred from the findings on hand and is verified with the aid of the functional(substitutional) operator. In terms of exponential function, we estimate $\mu$-delayed Mittag-Leffler type function. Existence uniqueness of solutions to nonlinear delayed Langevin fractional differential equations are obtained with regard to the weighted norm defined in accordance with exponential function. The notion of stability analysis in the sense of solutions to the described Langevin equations is discussed on the grounds of the fixed point approach. Numerical and simulated examples are shared to exemplify the theoretical findings. This paper provides novel results.

TITLE PAGE: Title: Letter to the Editor “Long-term outcomes of aortic root replacement for endocarditis”Article type : Letter to the editorCorrespondence : 1. Roomi RajaContact No: +923342946940 Email: Romirajagoindani@Yahoo.ComInstitute: Ziauddin UniveristyAddress: Hemilton Courts Block G-1 Flat 408 Teen Talwar Clifton KarachiCo-authors : 2. Satesh KumarContact: +92-3325252902 Email: Kewlanisatish@gmail.comInstitute: Shaheed Mohtarma Benazir Bhutto Medical College Liyari, KarachiAddress: Parsa citi Garden east, KarachiWord count: 380Conflict of interest; noneDisclosure; noneFunding; none

In patients unsuitable for transfemoral transcatheter aortic valve implantation (TF-TAVI) due to peripheral artery disease, another route such as trans-subclavian-axillary or transcarotid is a becoming alternative. The novel Myval transcatheter heart valve system technology is a second-generation balloon-expandable valve described by design innovations that promote accurate positioning of the valve and warrant accurate orthotopic valve deployment. To our knowledge, this is the first case report in the literature of successful transcarotid TAVI via the novel balloon-expandable Myval THV system under the local anesthesia for heavily calcific and stenotic abdominal aorta and subclavian arteries.

Lipomas are the most common benign soft tissue tumors. They usually occur in areas with abundant adipose tissue. Lipomas in the sole have been seldom reported. We present a patient with tumor of the plantar aspect of the foot, which was excised and histologically confirmed as fibrolipoma.

Appendiceal diverticulosis is a rare finding associated with appendiceal neoplasms. Both can masquerade as appendicitis in patients and are overlooked in differentials of right upper quadrant pain. A 37-year-old African American female presented with appendicitis-like symptoms to the emergency room with fever and leukocytosis. Appendectomy was performed with pathological evaluation revealing coexisting appendiceal diverticula and carcinoid of the appendix with lymphovascular invasion and mesoappendiceal involvement. In line with the National Comprehensive Cancer Network guidelines, right hemicolectomy with lymph node dissection was performed which was negative for neoplastic invasion but positive for colonic diverticulosis. While there have been many case reports of appendiceal diverticula with coexisting appendiceal carcinoid, a concurrent colonic diverticulum in the right hemicolectomy specimen during the oncologic resection of the appendiceal carcinoid has not been previously reported. We propose colonic diverticula as another possible feature that may be associated with appendiceal diverticula especially with an underlying appendiceal neoplasm.

Joint involvement in COVID-19 may occur at different stages of the disease and maybe represented by acute arthritis.We report Two cases of COVID-19.Both of our cases are consistent with what has been reported in the literature strengthen the necessity of wider studies to identify rheumatologic manifestations after surviving COVID-19.

Objective: To evaluate the perioperative clinical efficacy of preoperative human fibrinogen treatment in patients with acute Stanford type A aortic dissection (ATAAD). Methods: Data of 159 patients with ATAAD who underwent emergency surgical treatment in our hospital from January 2019 to December 2020 were retrospectively analyzed. Patients were divided into two groups according to whether human fibrinogen was administered before surgery. The preoperative clinical data, surgical data, postoperative data, complications related to the coagulation function, and mortality of the two groups were compared and analyzed. Results: The in-hospital mortality was similar in the two groups (2.9% versus 9.3%, P = 0.122). However, group A had a significantly shorter operation time (279.24±39.03 versus 298.24±45.90, P=0.008), lower intraoperative blood loss (240.48±96.75 versus 353.70±189.80, P＜0.001), and reduced intraoperative transfusion requirement of red blood cells (2.61±1.18 versus 6.05±1.86, P＜0.001). The postoperative suction drainage within 24 hours in group A was significantly decreased (243.24±201.52 versus 504.22±341.08，P=0.002). The incidence of postoperative acute kidney injury (AKI) in group A was lower than that in group B (3.8% versus 14.8%, P =0.023). Similarly, the incidence of postoperative hepatic insufficiency in group A was lower than that in group B (1.9% versus 9.3%, P =0.045). In group A, the mechanical ventilation time was shorter (47.68±28.61 versus 118.21±173.16, P=0.004) along with reduced ICU stay time (4.06±1.18 versus 8.09±9.42, P=0.003), and postoperative hospitalization days (19.20±14.60 versus 23.50±7.56, P=0.004). Conclusion: Preoperative administration of human fibrinogen in patients undergoing ATAAD surgery can effectively reduce the intraoperative blood loss, blood transfusion amount, shorten the operation time, reduce postoperative complications, and improve the early prognosis of patients, in addition to being highly safe.

A method to reduce crosstalk using TL-shaped defect microstrip structure (DMS) is proposed to solve the far-end crosstalk between microstrip lines. This method optimizes the ratio of the capacitive coupling and the inductive coupling between the coupled microstrip lines by etching the TL-shaped DMS on the microstrip line and reduces the strength of the electromagnetic (EM) coupling, which can achieve crosstalk suppression. The equivalent circuit model, S-parameters and full-wave EM simulations are used to analyze the crosstalk between the microstrip lines etched with and without the TL-shaped DMS. High Frequency Structure Simulator (HFSS) software simulation and samples test results show that the TL-shaped DMS can effectively reduce the far-end crosstalk while guaranteeing the transmission ability of microstrip line to the signal. The maximum far-end crosstalk can be reduced by 42dB in the frequency range of 0–8 GHz and the test results of the samples are in good agreement with the simulation results.

Gallbladder cancer is a rare but potentially fatal disease. It is often asymptomatic in early stages and is frequently found incidentally or during the workup for benign biliary disease. We present two patients who each had suspicious gallbladder imaging findings and highlight their differences on radiologic and pathologic examination.

Multi-attribute utility theory (MAUT) is a non-monetary approach used to quantify the difference between distinct alternatives considering decision-makers’ preferences to outcomes by assigning utility measures for each alternative. The main objective of using MAUT when evaluating different alternatives is to achieve Value for Money (VFM), meaning the best possible results based on the money spent. This paper describes the development of a decision-making framework proposed to assist the Florida Department of Transportation (FDOT) with selecting contractor compensation provisions in resurfacing Design-Bid-Build (DBB) projects. The framework facilitates the trade-offs among four decision objectives, if satisfied, to demonstrate value-for-money in FDOT resurfacing investments. The model is illustrated through a hypothetical resurfacing project. The development of the model includes defining four decision objectives. Six measures were proposed to evaluate the level of achievement of the four decision objectives.

Objectives. The aim of this study was to investigate the epidemiology of RSV bronchiolitis and the influence of meteorological and air pollutant factors on the isolation of RSV in infants admitted for viral bronchiolitis during three consecutive years, before and during the COVID-19 pandemic, in Bogota, Colombia, a middle-income country (MIC) with a tropical climate. Methods. An analytical cross-sectional study was conducted before and during the COVID-19 pandemic, including patients with a diagnosis of viral bronchiolitis admitted to all the hospitals of the city between January 2019 and November 2021. Predictor variables included meteorological and air pollutant parameters. We adjusted multivariable analysis to identify factors independently associated with isolation of RSV as the causative agent of viral bronchiolitis. Results. A total of 12,765 patients were included in the study. After controlling for potential confounders, it was found that age (OR 0.87; CI 95% 0.77–0.98; p=0.029), COVID-19 pandemic (OR 0.74; CI 95% 0.64–0.86; p<0.001), temperature (OR 1.85; CI 95% 1.47–2.33; p<0.001), and interaction terms between SES and NO2 (OR 1.04; CI 95% 1.01–1.07; p=0.002), and between rainfall and NO2 (OR 0.99; CI 95% 0.998–0.999; p=0.010) independently predicted the isolation of RSV as the causative agent of viral bronchiolitis in our sample of patients. Conclusions. The identified predictors for isolation of RSV as the causative agent of viral bronchiolitis provide additional scientific evidence that may be useful in the development of specific interventions aimed at ameliorating or preventing the impact of RSV in Bogota and probably other similar LMICs in high-risk infants.

Single-atom catalysts with optimal atom utilization and outstanding activity have penetrated the frontier of heterogeneous catalysis. However, the large-scale synthesis of this class of catalysts is still a bottleneck for their industrialization. Herein, we suggest a two-stage micro-dispersion approach to synthesize mesoporous MgAl2O4-supported atomically dispersed Rh, which is more competitive than the batch method for boosting the uniform dispersion of Rh. By increasing the Rh loading, single-atom catalysts (SACs, < 0.05wt%), single-atom catalysts + nanoparticle catalysts (0.05–0.17 wt%), and nanoparticle catalyst (NPCs, 0.17–1.10 wt%) were obtained. For n-octane steam reforming, the turnover frequency of the SAC (0.01 wt%) was approximately 30 times that of the NPC (1.10 wt%), while the Rh amount of the SAC was only 3% that of the NPC for the same fuel conversion. Under a high-temperature (750 ℃) steam atmosphere for 15 h, the hydrogen formation rate only declined from 25.1 to 23.8 mol/mol-C8H18.

Background and purpose: Persistent endoplasmic reticulum (ER) stress and its deleterious crosstalk with mitochondria trigger oxidative stress, mitochondrial dysfunction and inflammation contributing to the pathophysiology of a myriad of cardiovascular diseases linked with hypertension such as abdominal aortic aneurysm (AAA) and cardiac hypertrophy. The purpose of this work was to determine whether inhibition of ER and mitochondrial stress is effective preventing aneurysm development and cardiac hypertrophy in angiotensin II (AngII)-infused apolipoprotein-E-deficient (ApoE−/−) mice. Experimental approach and results: The expression of ER stress markers (Hspa5, Atf4, Atf6, Chop and Ern1) was up-regulated in aneurysmal abdominal aortas from AngII-infused ApoE−/−mice. The treatment with ER stress inhibitors improved survival, decreased systolic blood pressure, limited the incidence and severity of AAA and reduced the AngII-induced increase of aortic diameter evaluated by ultrasonography. These beneficial effects were mimicked by the mitochondria-targeted tetrapeptide SS31. The disorganisation of elastin and collagen fibres, the increased expression of metalloproteinases and pro-inflammatory markers and the infiltration of immune cells induced by AngII in the abdominal aorta were effectively reduced by both, ER inhibitors and SS31. Additionally, treatment with SS31 prevented the alteration of mitochondrial dysfunction and reduced ER stress markers expression and plasmatic ROS levels. Mechanistically, CHOP deficiency in ApoE−/−mice reduced the blood pressure and the incidence of AAA. Interestingly, both pharmacological interventions and CHOP deficiency attenuated AngII-induced cardiac hypertrophic remodelling and improved systolic and diastolic function. Conclusions: Our data evidence that inhibition of ER and mitochondrial stress limits abdominal aortic aneurysm formation, increases survival and ameliorates hypertensive cardiac hypertrophy.

Latour does not seek any “hidden” reasons behind actions; there is not a dictionary or encyclopedia explaining the sources of the behaviors of the actors. No meta-language is in question. The analyst cannot address any invisible agency. If an agency is invisible, then it has no effect, therefore it is not an agency. If an analyst says: “No one mentions it. For Latour, agency is not limited to human beings, but objects should also be counted as agents which is one of the most attractive aspect of actor-network theory.

Long-term monitoring of ice-dammed lake development are important for understanding the process of lake storage and outburst. Based on remote sensing observations for the period 1972-2020, we obtained so far the most detailed reconstruction of the filling and drain of Kyagar lake, a typical annually ice-dammed lake in the north Karakoram. We show that annually repeated lake filling-drains were detected by satellite observations during two periods:1996 to 2009 and 2015 to 2020, while between 2009 and 2015 none obvious outburst occurred. These two intermitted periods with regular annual cycles of lake outburst were likely related to the long-term cycle of glacier surge dynamics, which show two remarkable surge-induced terminus accelerations during 1995-1997 and 2014-2016. Following each surge, the maximum lake areas were decreased by about 33% from 1996-2009 and by about 88% from 2015-2020. With climate warming and the thinning of the ice-dam, the storage capacity of glacial lake will likely continue decrease in the future, and the risk of lake outburst flood thus somehow decrease. Repeated drainage following filling exacer-bates the depletion of material at the glacier terminal, leading to the cessation of storage and creating the conditions for the next glacial surge to occur, thus creating a long-term cycling process. Together with the uncertainty and intensified climate changes, it suggests that a close monitoring of the glacial lake development and glacier dynamics would be still important.

Speed of life and reproductive strategy form the two major axes that organise variation in life history strategies across plant and animal species. This cross-taxonomical structuring can inform on the sensitivity of species to environmental change. However, predictions based on broad cross-taxonomical patterns do not necessarily align with those from detailed research on a smaller range of species. Here, we use Dynamic Energy Budget Integral Projection Models (DEB-IPMs) to quantify the extent to which patterns in the life history strategies of a large and diverse taxonomic class of fish (Actinopterygii) inform on their sensitivity to environmental change. By accounting for additional complexity in individual life histories, the classical association between life history strategies and sensitivity to environmental change breaks down. We discuss which trait-based approach is best suited to tackle challenges in linking life histories to population responses to change, and summarise our perspective in a conceptual framework

Total Anomalous Pulmonary Venous Connection combined with Single Ventricle represents a cardiac and extra-cardiac diagnosis that may benefit from alternative additional imaging to reach a complete anatomical diagnosis and continued treatment strategy.

Mesenteric Lipoma is very rare. Diagnosis is challenging because of nonspecific clinical presentation. Complete resection of the lipoma is proposed to relieve pain, and prevent complications. We report a case of mesenteric lipoma revealed by chronic abdominal pain and we performed a litterature review regarding this rare condition.

Portal hypertension is a rare complication of liver metastases. We present a case with a history of two months of progressive painless abdominal distension and progressively increasing yellowish discoloration of the eyes. A diagnosis of multiple metastases from breast carcinoma to the liver leading to portal hypertension was made.

Concomitant bilateral direct, indirect, and femoral inguinal hernia is a rare condition that can lead to complications such as incarceration, strangulation, and postoperative recurrence. So, it is important to choose the most useful diagnostic and treatment way.