Background and Aim: Cancer significantly reduces quality of life for patients and families, demanding effective palliative care solutions; telemedicine emerges as a transformative approach to enhance care accessibility and efficiency. This review systematically evaluates telemedicine’s potential in palliative oncology, examining how digital tools can deliver timely, personalized support while overcoming geographical and resource barriers. By synthesizing current evidence, we assess implementation challenges and benefits, ultimately aiming to establish best practices for technology-integrated palliative care models that address both clinical and psychosocial needs in cancer management. Methodology: This research, in terms of nature and method, was a library-based study (systematic review) that utilized the results of previous research related to the topic to explain and conduct the work. The statistical population of this research includes all studies related to the topic that have been indexed in the last 10 years in online databases such as ISI, SID, Magiran, Science Direct, Google Scholar, Scopus, Springer Nature, and ISC. Among these, 72 studies related to the topic were selected using convenience sampling. Results: The reviewed studies demonstrate that telemedicine packages effectively enhance cancer care delivery by improving patient access to follow-up services, reducing unnecessary hospital visits, and minimizing post-discharge referrals. These solutions empower caregivers through online training in specialized care techniques while teaching patients self-management skills. However, widespread adoption faces challenges including technological limitations, data privacy concerns, and the absence of standardized regulatory frameworks. Conclusion: The findings suggest that measures of affected person pride, first-class of lifestyles increased, alongside, and decreased fitness care device costs, and must be emphasized with inside the acceptability and adoptability reviews of far flung palliative care. Thus, upcoming research want to research if and the way promising technology can permit greater green outpatient care to make sure top of the line assist for patients (such as oncological ones).