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Ana Muñoz Jurado
Ana Muñoz Jurado

Public Documents 1
Brain stimulation as a therapy in Long-Covid: A Narrative Review
Ana Muñoz Jurado
Begoña Mª Escribano

Ana Muñoz Jurado

and 3 more

April 23, 2025
Long-COVID syndrome is a prevalent condition among the group of people who are infected by this virus. However, there is still no defined treatment for this syndrome. This is because long-COVID is a very heterogeneous syndrome characterized by triggering different symptoms in each patient. However, the most frequently reported symptoms are fatigue, cognitive dysfunction, anxiety and depression, which have a significant socioeconomic impact. The neurological nature of these symptoms has raised the possibility of using brain stimulation therapies for their treatment. Therefore, the objective of this literature review is to evaluate noninvasive therapies as possible treatments for this disease, highlighting the specific effects of one of these therapies, transcranial magnetic stimulation (TMS). The results of the different studies carried out so far, which have used transcranial direct current stimulation, transcutaneous vagus nerve stimulation or TMS, have shown that these techniques can be effective in treating the clinical symptoms caused by post-COVID syndrome. However, more studies are needed to evaluate the effectiveness of this type of therapy on these symptoms, since the great heterogeneity of this syndrome represents a great challenge for public health and a significant socioeconomic cost, which requires investing in the study of new treatment approaches.

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