Myopericytoma is a relatively rare benign tumor that arises from perivascular myoid cells, these tumors typically occur in the skin, superficial soft tissues, or rarely in deeper tissues such as muscle. These are slow-growing and non-aggressive, but they can vary in size and may present as solitary nodules or masses.We describe a case of a 36-year-old male who presented with knee pain and swelling, the MRI of the knee was suggestive of soft tissue lesion in the intraarticular region. The lesion was excised, and diagnosed as Myopericytoma on histopathology.Clinically, Myopericytoma are characterized by their firm texture and well-circumscribed but unencapsulated borders. They are usually painless unless they compress nearby structures. Diagnosis often involves a biopsy for histological examination to confirm the presence of perivascular myoid cells and to rule out mimics such as solitary fibrous tumor, myofibroma and glomus tumor. Treatment typically involves surgical excision, and the prognosis is generally good with low rates of recurrence after complete removal.