Lower respiratory tract infections (LRTIs) are one of the leading causes of hospitalization in children, with their associated respiratory pathogens typically following seasonal epidemic patterns. However, the COVID-19 pandemic has profoundly altered the landscape of pediatric respiratory infections, causing unprecedented shifts in the epidemiology of common respiratory pathogens. To date, long-term epidemiological surveillance remains limited, particularly in pediatric populations. We aimed to investigate the dynamic changes of the etiologies of hospital admissions for common pathogen-associated LRTIs over 8 years, and the results indicate that, in the pre-pandemic era, the most common causes of LRTIs were Mycoplasma pneumoniae (MP) (34.98%), respiratory syncytial virus (RSV), (20.62%) and parainfluenza virus (PIV) (8.16%). Adenovirus (ADV) has surged in the post-pandemic era, surpassing PIV to become one of the leading causes of hospitalized LRTIs cases in children. In contrast, influenza B virus was not significantly affected by NPIs ( P>0.05). Additionally, we observed a rising age trend in children with LRTIs associated with RSV, PIV, ADV, and Influenza A virus (IAV). Furthermore, a model by seasonal autoregressive integrated moving average (SARIMA) time series suggested that the lifting of NPIs led to a rapid rebound of respiratory pathogens, with a gradual return to seasonal trends.