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Baoqing Xu
Baoqing Xu

Public Documents 1
γδT cells in IBD: beneficial or detrimental?
Baoqing Xu
Jianbin Ji

Baoqing Xu

and 8 more

March 11, 2025
Immune cells are crucial in the body’s defence mechanisms. γδT cells are a non-traditional subpopulation of T cells with distinct structures and functions. γδT cells exhibit unique immune functions, contribute to both innate and adaptive immunity, and are implicated in several immune disorders. An increasing number of studies have identified changes in γδT cell numbers, types, and secreted cytokines in IBD. However, whether γδT cells in IBD are beneficial or detrimental remains controversial. Several studies have explored γδT cell-based therapies for immune disorders, and γδT cell-based therapy for IBD has emerged as a promising research direction. There are numerous reviews of γδT cells and autoimmune diseases, but few reviews focus on γδT and IBD. Therefore, this article briefly summarizes the current understanding of γδT cells in IBD.

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