Respiratory Tract Infections are the major health hazard to humanity, nowadays. This research aims at the development and implementation of evidence-based intervention at primary healthcare level, in order to control Respiratory Tract Infections, called Intervention Mapping(IM). It comprises multiple phases, focussing on specific needs of the target population and ensuring that intervention should be based on behavioral and systematic change. The study has a mixed design, quantitative and qualitative approach, involving multiple stakeholders, community's participation and healthcare worker's collaboration, to control infectious diseases at primary healthcare level and thereby to reduce the burden of diseases. The study comprises three phases including a pre-intervention phase in which disease load was assessed and the need of particular intervention was analyzed. A multi-targeted public health intervention, incorporating health education, environmental modification, and policy changes, was designed and applied after community analysis. This phase is preceded by the insight development phase which showcased the vitality of community based intervention. The infectivity of respiratory tract infections is studied under two categories. The gender based segregation provided an insight on the spread of respiratory tract infections in males and females, and a subsequent reduction in disease load among both the genders. The second form of study is focussed of age based separation and disease load. The effectiveness of the research can be analyzed by a remarkable decrease in the respiratory diseases in a community. According to the study's findings, epidemiologic burden of respiratory infectious diseases can be trimmed by community strengthening activities including population sensitization, community health initiatives, targeting at-risk population, and engaging key actors of the area. This translational research provides a policy recommendation for health promotion, disease prevention, and intervention mapping in a resource-constrained environment. However, the pathway stipulated by the study revolves around shifting from a curative model of healthcare to the preventive model at primary health level.