INTRODUCTIONAn 11-month-old castrated male Maine Coon originally imported from a known breeder in Budapest, presented to WestVet with a 12-day history of progressive paraparesis, anorexia, lethargy, non-specific pain, and difficulty defecating. Full body CT scan with the referring veterinarian showed pulmonary changes suggestive of pneumonia or transient atelectasis, but no evidence of aggressive, acute traumatic, or other osseous lesions of the spine. Contrast-enhanced MRI of the brain and thoracolumbar spine at the referral hospital revealed two plaque-like mass lesions associated with the right frontal bone and ventral calvarium near the brainstem with a separate lesion of the thoracic spinal cord. During anesthetic recovery, a single, smooth, non-ulcerated, pink, fleshy mass, ~1x2cm was noted in the inferior fornix of the left eye. The mass was aspirated several times with 22- and 25-gauge needles. The cytology read by a clinical pathologist was consistent with large cell lymphoma. The cat started treatment with oral lomustine and its neurologic status remained static. The cat went home following 8 days of hospitalization with oral medications and plan to follow up with the primary care veterinarian for additional lomustine treatment. At 18 days post-discharge, the cat was euthanized for undescribed progression of clinical signs.