IntroductionClozapine is an antipsychotic which always used in treatment-resistant schizophrenia and can reduce suicide rate[1]. It is associated with severe cardiac complications including myocarditis and cardiomyopathy in psychotic patients[2]. Left ventricular myocardial insufficiency cardiomyopathy (LVNC) has been reported in patients with long-term use of clozapine, but it was rare in the right ventricle. [3]. Given the current increase in the prescription of clozapine, it seems important to know better adverse effects during pregnancy and lactation as well as its risk profile for neonatal outcome. Clozapine can cross the placental barrier, decreased fetal heart rate variability and absence of accelerations have been found in previous cases[4,5,6]. However, neonatal RVNC induced by clozapine during pregnancy and lactation has never been reported before. The case we report may increase the safety data of clozapine.