loading page

Case Series of Intracranial Central Primitive Neuroectodermal Tumor in Two Adults Treated with Craniospinal Irradiation
  • +4
  • Shubham Dokania,
  • Sambit Nanda S,
  • Ipsita Dhal,
  • Ajay Choubey K,
  • Ninad Patil H,
  • Jhansi Pattanaik,
  • Ashutosh Mukherji
Shubham Dokania
Homi Bhabha Cancer Hospital
Author Profile
Sambit Nanda S
Homi Bhabha Cancer Hospital
Author Profile
Ipsita Dhal
Homi Bhabha Cancer Hospital
Author Profile
Ajay Choubey K
Homi Bhabha Cancer Hospital
Author Profile
Ninad Patil H
Homi Bhabha Cancer Hospital
Author Profile
Jhansi Pattanaik
Homi Bhabha Cancer Hospital

Corresponding Author:jhansi.pattanaik@gmail.com

Author Profile
Ashutosh Mukherji
Homi Bhabha Cancer Hospital
Author Profile

Abstract

Ewing sarcomas (ESs) and primitive neuroectodermal tumours (PNETs) exhibit identical genetic and histological characteristics, hence collectively denoted as ESs/PNETs, originating from the neuroectoderm and primarily consisting of primitive neuroectodermal cells. PNETs occur primarily in the cerebrum. They constitute 3-5% of all paediatric brain tumours. This case report describes two cases of intracranial central PNET with negative IHC and chromosomal markers in adult patients treated with craniospinal irradiation (CSI) and focal radiotherapy boost with concurrent and adjuvant chemotherapy.