not-yet-known not-yet-known not-yet-known unknown Purpose The prevalence and time trend of prescription practices provide context to pharmacoepidemiological studies. This study aims to present accessible information on prescription practices over time within Taiwan’s healthcare system to aid healthcare professionals, policymakers, and researchers. Methods Data were sourced from the Taiwan National Health Insurance Research Databases, compiling prescribing rates for specific ATC (Anatomical Therapeutic Chemical) drug groups stratified by age and sex for the years 2005, 2010, 2015, and 2020. Information on drug doses, durations, subtypes, brands, co-prescribed medications, and co-occurring diagnoses was not included. Results The dataset includes 400 ATC drug groups and over 19,822 data points. Analysis reveals diverse prescribing trends, such as the increased prescribing rates for statins from 2005 to 2020, especially among individuals in their 60s and 70s. Significant fluctuations in drug utilization patterns were observed, which may reflect broader health trends and policy impacts over the periods examined. Conclusion The ”Prescribing in Taiwan” data resource serves as a valuable tool to improve research efficiency and transparency by providing preliminary data access and reducing barriers for researchers. Enhancements to include more detailed data could further support pharmacoepidemiological research and healthcare decision-making.