A computational fluid dynamics study was carried out on the atomization characteristics of a certain type of dual-orifice nozzles centrifugal nozzle. The reliability of the numerical simulation was verified by using the simulation of two-phase flow with Large-Eddy Simulation (LES) and combining the results of experimental studies on nozzle atomization. Ultimately, the atomization characteristics of the two-way centrifugal nozzle under different working conditions were obtained. The results showed that: when the sub fuel road worked alone, with the increased fuel pressure, the momentum ratio of the liquid increased; the atomization cone angle was affected by the fuel supply pressure at low supply pressure, and after the increased pressure affected by the structure of the nozzle, the size of the atomization cone angle tended to increase first and then decrease. When dual fuel roads worked at the same time, the main fuel road produced a convergence of fuel from the droplets to the fuel sheet. The change of the atomization field was less affected by the sub fuel road and mainly by the main fuel road whose fluid conditions determined the entire atomization field of the change of the physical parameters. When the fuel supply pressure was lower, the liquid film surface produced a kind of surface wave that varied along the sinusoidal direction of the liquid film surface. At this time, the dominant liquid fragmentation was the Kelvin-Helmholtz (K-H) instability. When the fuel supply pressure was higher, the liquid column fragmentation was dominated by the Rayleigh-Taylor (R-T) instability.