Background and aim: The reflux symptoms score -12 (RSS-12) is a validated questionnaire with good sensitivity and specificity for diagnosing laryngopharyngeal reflux disease (LPRD). However, the correlation between RSS-12 and reflux finding score (RFS) in patients with clinical symptoms suggestive of LPR has not been investigated. In this study, we examined such correlation. Patients and methods: We conducted cohort cross sectional study over 6 months duration in total of 105 patients with typical gastroesophageal reflux disease (GERD ) symptoms associated with LPR symptoms based on RSS-12.We excluded patients with any medical problems or lifestyle habits that could induce similar symptoms. The study participants underwent a telescopic laryngeal examination and the RFS was calculated. Results: The prevalence of LPRD (RFS > 7) in patients with clinical symptoms of GERD and LPR was 14.2% (15 patients). Laryngoscopic abnormalities unrelated to LPRD were present in 16 patients (15.2%). RSS-12 had strong positive correlation with RFS. Conclusion: In patients with clinical symptoms of LPR, RSS-12 strongly predicts the diagnosis of LPRD.