IntroductionBrevundimonas vesicularis belongs to theAlphaproteobacteria class and Caulobacteraceae family [1], which was previously assigned to Pseudomonas vesicularis but later reclassified into a new genus “Brevundimonas ” by Segers et al. in 1994 [2]. It is an aerobic, non-lactose, oxidase and catalase positive, flagellated Gram-negative rod that can be isolated from both environmental and clinical specimens [3]. The organism can be isolated in the laboratory on blood or chocolate agar. However, not all strains grow on MacConkey agar [4].It is an opportunistic pathogen that is associated with septicemia, pneumonia, meningitis, septic arthritis, urinary tract infection in children and cervicitis in women [5-7]. It mainly infects patients with underlying health conditions such as congenital heart disease, respiratory distress syndrome, multiple congenital cerebral anomalies, and meconium aspiration syndrome [8]. It affects patients with foreign bodies, immunocompromised individuals and rarely those without predisposing disease [5, 9]. Many of these instances of infection were either hospital or community-acquired [1, 6].B. vesicularis is an emerging global opportunistic pathogen of concern. However, a few invasive B. vesicularis infections exist in the literature [1, 6-12]. Here, we report a case of B. vesicularis sepsis in a 2-month-old child with cyanotic congenital heart disease at a hospital in rural Gambia.