【Abstract】Promoting the expansion and sinking of high-quality medical resources and regional balanced layout is an important part of building a high-quality and efficient medical and healthcare service system, and an important healthcare reform initiative to alleviate the problem of the public’s difficulty in accessing medical care and the high cost of medical care. Over the years, Tianjin Medical University General Hospital has been actively implementing the people-centered development ideology, focusing on promoting the high-quality development of the hospital, plowing into the remote diagnosis and treatment of Internet hospitals and the construction of intelligent medical care, and exploring efficient paths and modes of expanding and sinking high-quality medical resources according to local conditions. Based on its practical exploration, this paper will analyze the macro level of horizontal comparison of healthcare reform models within and outside the province, the meso level of the overall regulation of the healthcare system in Tianjin, and the micro level of the internal healthcare reform path of the General Hospital in an attempt to contribute to the implementation of the 20th National Congress, which proposes to ”promote the expansion of high-quality healthcare resources and the balanced layout of the region”.