Mouse models to explore the biological and organismic roleof DNA polymerase betaRobert W. Sobol1,*1Department of Pathology and Laboratory Medicine, Warren Alpert Medical School & Legorreta Cancer Center, Brown University, Providence, RI 02912Running title : DNA polymerase beta mouse modelsKeywords : DNA polymerase beta, base excision repair, mouse, mouse models, transgenic, knock-out, knock-in, CRISPR/Cas9*Address correspondence to :Robert W. Sobol, Ph.D.Department of Pathology and Laboratory MedicineWarrant Alpert Medical School & Legorreta Cancer CenterBrown University, Providence, RI 02912rwsobol@brown.edu