This case report describes a pediatric patient requiring enteral tube treatment with isavuconazole for an invasive fungal infection post-hematopoietic stem cell transplantation. Previously reported literature in adult patients support this administration technique, however, no literature specific to pediatric patients exists. This brief report will examine subsequent trough concentrations of enteral tube administration of isavuconazole capsules for a pediatric patient being treated with a concomitant interacting medication.