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SUMIT SHEORAN

Public Documents 2
Antioxidant activity of Leptocarpha rivularis DC flower extract and Globularia alypum...
SUMIT SHEORAN
Swati  arora

SUMIT SHEORAN

and 2 more

February 23, 2024
The aim of this analysis was to look into the complete phenolic and flavonoid contents, and also the antioxidant activity, of leaf extracted from Globularia alypum L. collected in the Taza region of northeast Morocco and flower derives from Leptocarpha rivularis DC. Consequently, the extracts’ individual phenolics and volatiles were measured. Soxhlet extraction was used to produce organic extracts of this plant using two separate solvents, ethyl acetate and chloroform. The antioxidant ability of leaf extracts was assessed using DPPH, ABTS, and FRAP assays; antioxidant and anticancer viability was evaluated in Leptocarpha rivularis DC flower specimens employing four solvents (n-hexane (Hex), dichloromethane (DCM), and acetone) (DCM),ethyl acetate (AcOEt), and ethanol (EtOH)). The antioxidant activity (2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH), ferric reducing antioxidant ability (FRAP), overall reactive antioxidant properties (TRAP), and oxygen radical absorbance capability (ORAC) of extracts were contrasted through a defined value of reduced/oxidized glutathione (GSH/GSSG). The findings affirm the value of this plant as a sources of antioxidants.
Exploring the therapeutic role of Anti-microbial peptides (AMPs) via a bioinformatic...
SUMIT SHEORAN
Swati  arora

SUMIT SHEORAN

and 3 more

January 31, 2024
Pathogens are spreading at an alarming rate throughout the world, posing a global health threat. Because present treatment options have mostly failed, new antibiotics are in high demand. Antimicrobial peptides (AMPs) have emerged as a viable option in this circumstance due to their broad-spectrum action, fast death, and frequently cell selectivity. They are made up of several functional molecules with multiple characteristics and varying biological activity. Their action mechanism is uniquely changed according to the distinct amino acids and components in its composition. Antimicrobial peptides are been derived from many sources i.e. plants, Animals, marine etc. They have therapeutic promise, however their usage is restricted due to its short plasma half-life. With the aid of biotechnological techniques, AMP manufacturing may be accomplished at a small price. As a result, once these obstacles are addressed, the development of effective and long-lasting antimicrobial medicines is anticipated. In this review article explains about the applications of bioinformatics, mode of action, sources and many more.

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