This article employs structural realism indicators to predict the likelihood of a great power war in today’s multipolar world. Focusing on key indicators such as changes in the balance of power, alliance systems, military expenditure, and the intensity of competition over strategic resources and regions, the analysis aims to establish a theoretical foundation for assessing the risk of conflict among major powers in Europe and beyond. Drawing on historical precedents and contemporary geopolitical trends, the study evaluates the dynamics of international relations through the structural realist framework. By examining the evolving power structures and strategic behaviors of major states, the article seeks to identify patterns that may indicate an increased risk of great power conflicts. The multifaceted approach integrates both historical insights and current realities, offering a comprehensive perspective on the potential triggers and dynamics of great power wars in the complex landscape of a multipolar world. This research contributes to a deeper understanding of the structural factors that may influence the emergence of conflicts among major powers, providing valuable insights for policymakers, scholars, and analysts grappling with global security challenges.