The novel coronavirus (SARS-CoV-2) has caused a global pandemic, which can cause cough, fever, muscle aches, fatigue and, sore throat. However, most people do not know how to cope with them so that some patients may progress to pneumonia and even severe disease. Therefore, it’s crucial to effectively cope with COVID-19 infection at home to reduce the rate of hospitalization, ease the burden of healthcare systems, alleviate patients’ suffering, and shorten the illness duration. In this regard, we aim to describe the symptom groups of the recently epidemic BF.7 variant strain infection, and summarize previous clinical experience and expert guidelines, the following home care measures for the five main symptoms were proposed. We hope that these strategies will serve as a reference for home care of patients and help them take appropriate measures to manage their symptoms.