The drugs are used at great degree for the medical care, illnesses in animals and food packaging to increase food stability. Still, the reports have showed the likely existence of drug portions in it, assuring one of the major people worries for food assurance. Thus, it is extremely in demand to plan more safe scientific methods to observe drug components in water or food. Therefore, in this work we have synthesized cellulose nanocomposite for Ciprofloxacin (Cip) absorption, detection, or removal and found better results. Besides, antimicrobial activity found excellent results against carbonized material. Composite characterized by Fourier-transform infrared (FTIR), Transmission electron microscope (TEM), Field-emission scanning electron microscopy (FE-SEM) and X-ray photoelectron spectroscopy (XPS).