Visible/infrared imagery from passive satellites is commonly relied upon to study low cloud microphysics over ocean, including for the Southern Ocean (SO), but relatively little validation has been undertaken for the SO. In this article, we compare low-cloud effective radius (re), cloud droplet number concentration (Nd) and cloud liquid water path (LWP) retrievals from the NASA Moderate Imaging Spectroradiometer (MODIS) with surface measurements collected during the Macquarie Island Cloud & Radiation Experiment (MICRE). MODIS 3.7-μm band retrievals show little bias and moderately good correlation relative to MICRE retrievals for liquid-phase low clouds when restricted to Solar Zenith Angles < 65o on spatial scales of 50 to 100 km. However, the low overall bias in 3.7-μm band effective radius (re 3.7) retrievals partly results from cancellation of errors: re 3.7 is overestimated for non-to-lightly precipitating clouds and underestimated for heavier drizzling clouds by ~1 to 1.5 μm. In contrast, 1.6-μm, and 2.1-μm band re retrievals are biased high. Nd may likewise be slightly under- or overestimated depending on the concentration, but there is insufficient data to provide confidence in this result. Interestingly, a composite of MODIS retrievals from 2002-2020 shows a distinct region of enhanced cloud cover and Nd (and lower re) in the wake of Macquarie Island associated with orographic cloud formation. MODIS retrievals of aerosol optical depth (AOD) and Angstrom Exponent (AE) upwind and downwind of the island do not differ significantly. Comparison with MICRE measurements suggests that MODIS Collection-6 AOD retrievals are reasonable, while AE is problematically large.