Extranodal NK/T-cell lymphoma, nasal type – A case report highlighting the differential diagnosis of lesions of the face.Authors: Leonor Dias1; Henrique Messias, MD MSc2,3*; Carlos Zagalo, MD PhD2; Carla Alves, MD4; Gonçalo Esteves, MD4; Pedro Gomes, MD2Affiliations:1 University of Lisbon, Faculty of Medicine, Portugal.2 Head and Neck Surgery department, Portuguese Institute of Oncology Francisco Gentil, Lisbon, Portugal.3 Division of Health Sciences, University of Edinburgh, United Kingdom.4 Pathological Anatomy department, Portuguese Institute of Oncology Francisco Gentil, Lisbon, Portugal.* Corresponding author:Henrique Messias, MD MScHead and Neck Surgery department, Portuguese Institute of Oncology of Lisbon Francisco Gentil,Rua Professor Lima Basto, 1099-023 Lisboa, Portugal Tel: +351913858593, E-mail: v1hmessi@ed.ac.uk

Compressive goiter hiding clear cell renal cell carcinoma metastases to the thyroid gland – report of a rare case and literature review.Authors: Chuyao Ying1; Henrique Messias, MD MSc2,3*; Carlos Zagalo, MD PhD2; Saudade André, MD PhD4; Pedro Gomes, MD2Affiliations:1 University of Lisbon, Faculty of Medicine, Portugal.2 Head and Neck Surgery department, Portuguese Institute of Oncology Francisco Gentil, Lisbon, Portugal.3 Division of Health Sciences, University of Edinburgh, United Kingdom.4 Pathological Anatomy department, Portuguese Institute of Oncology Francisco Gentil, Lisbon, Portugal.* Corresponding author:Henrique Messias, MD MScHead and Neck Surgery department, Portuguese Institute of Oncology of Lisbon Francisco Gentil,Rua Professor Lima Basto, 1099-023 Lisboa, Portugal Tel: +351913858593, E-mail: v1hmessi@ed.ac.uk

A document by Patrícia Bernardo. Click on the document to view its contents.

Background Papillary thyroid carcinoma (PTC) primarily located in the pyramidal lobe of the thyroid gland is extremely rare, so the clinical and pathological features are not well understood. Case The authors describe a case of multifocal PTC with larger pyramidal lobe tumour, in a 77-year-old female patient who underwent en bloc total thyroidectomy with pyramidal lobe, hyoid bone and cervical lymph node excision. Conclusion In line with the present case, current literature reports a greater presence of worse prognostic factors, namely extrathyroidal extension, advanced T stage or presence of cervical lymph node metastasis. Recently, a new classification has been suggested – Upper Neck Papillary Thyroid Cancer (UPTC) – which encompasses these carcinomas, Delphi ganglion metastases and thyroglossal duct cyst carcinomas, with potential clinical and therapeutic implications, particularly the need for orthotopic thyroidectomy. Also, the complete excision of the pyramidal lobe during thyroidectomy may influence the success of radioactive iodine therapy and the patient’s follow-up surveillance.