Hantaviridae currently encompasses seven genera and 54 species. Multiple hantaviruses, such as Hantaan virus, Seoul virus, Dobrava-Belgrade virus, Puumala virus, Andes virus, and Sin Nombre virus, are highly pathogenic to humans. They cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome or hantavirus pulmonary syndrome (HCPS/HPS) in many countries. Some hantaviruses infect wild or domestic animals without causing severe symptoms. Rodents, shrews, and bats are reservoirs of various mammalian hantaviruses. Studies on the genomics, taxonomy, evolution, replication, transmission, pathogenicity, and control of hantaviruses, as well as patient treatment, have made significant advances in recent years. Meanwhile, novel hantaviruses infecting bats, rodents, shrews, amphibians, and fish have been identified. This systematic review compiles these advancements to aid researchers and the public in better recognizing this zoonotic virus family with global public health significance.

1. A survey on the recent COVID-19 epidemic in China was conducted. 2. The epidemic likely made over 85% of people in China sick in December 2022. 3. The epidemic likely ended in early January 2023. 4. The epidemic had the features of spreading more rapidly and widely and having a higher symptomatic rate than previously thought. 5. The above features could lead to many severe cases and deaths due to the shortages of medical resources. 6. The above features greatly enhanced the population immunity in China, which will accelerate the end of the COVID-19 pandemic and reduce the emergence of risky variants of SARS-CoV-2 in China.