Background: Left atrial appendage occlusion (LAAO) in the treatment of atrial fibrillation (AF) has become a hot topic in clinical research in recent years. Case presentation: we report a 68-year-old female patient who was admitted for “recurrent palpitations for three years,” with an electrocardiogram finding of atrial fibrillation (Figure [1](#fig-cap-0001)). The diagnosis upon admission was: (1) arrhythmia: paroxysmal AF (CHA2DS2-VASc: 4 points, HAS-BLED: 3 points), (2) Grade 3 hypertension, and (3) carotid plaque with internal carotid artery stenosis. The patient had a history of AF for three years with poor drug treatment effect. The patient was unable to tolerate anticoagulation therapy. We gave the patient a one-stop procedure treatment of “AF radiofrequency ablation + LAAO” under the guidance of 3D printing technology. There was no recurrence of AF or paravalvular leakage at the three-month and one-year follow-ups. Conclusions: The 3D printing technology guide the one-stop operation of “AF radiofrequency ablation + LAAO” is helpful. But it whether can improve the prognosis and quality of life of patients, further multi-center research and large data statistics are required.

A patient presented to our hospital with myocarditis caused by mushroom poisoning. The early ECG changes in this patient were very similar to the ECG of hyperacute ST-segment elevation myocardial infarction (STMEI) or hyperkalemia, but further tests eliminated these options. The patient was fully treated by timely hemodialysis treatment, confirming the diagnosis of mushroom poisoning-induced myocarditis.Although not specific to mushroom poisoning myocarditis, our experience shows that the observed ECG changes. Our findings have the potential to help diagnose and manage this potentially fatal disease in the future.