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Coexistence of anti-MDA5 and anti-PL-7 in a patient with dermatomyositis: a case report
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  • Hongyan Fu,
  • Shaofeng Sun,
  • Hong Zhang,
  • Shuhong Chi,
  • Weirong Ma,
  • Guilan Yang,
  • juan chen
Hongyan Fu
General Hospital of Ningxia Medical University

Corresponding Author:fhy792882139@163.com

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Shaofeng Sun
General Hospital of Ningxia Medical University
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Hong Zhang
General Hospital of Ningxia Medical University
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Shuhong Chi
General Hospital of Ningxia Medical University
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Weirong Ma
General Hospital of Ningxia Medical University
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Guilan Yang
General Hospital of Ningxia Medical University
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juan chen
General Hospital of Ningxia Medical University
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Abstract

Anti-melanoma differentiation-associated gene 5 (anti-MDA5) and anti-threonyl-tRNA synthetase (anti-PL-7) are myositis-specific autoantibodies, associated with rapidly progressive interstitial lung disease (RP-ILD). A 41-year-old woman presented productive cough, dyspnea, and muscle pain. Anti-MDA5 and anti-PL-7 were double-positive. The patient was diagnosed with dermatomyositis-associated ILD, and responded successfully to glucocorticoids and immunosuppressants.
22 Jun 2022Submitted to Clinical Case Reports
23 Jun 2022Submission Checks Completed
23 Jun 2022Assigned to Editor
04 Jul 2022Reviewer(s) Assigned
18 Sep 2022Review(s) Completed, Editorial Evaluation Pending
17 Nov 2022Editorial Decision: Revise Minor
30 Nov 20221st Revision Received
30 Nov 2022Submission Checks Completed
30 Nov 2022Assigned to Editor
30 Nov 2022Review(s) Completed, Editorial Evaluation Pending
27 Dec 2022Editorial Decision: Accept