Bacterial keratitis is one of the major origins of keratitis, can cause corneal blindness, and is an important ophthalmic emergency. Antibiotic resistance results in failure to eliminate bacterial keratitis in many cases. This study aimed to investigate the bacterial keratitis and antibiotic resistance rate in Australia. Systematic literature surfing was done by considering all published articles focused on keratitis in Australia, and articles were retrieved from different databases, including Web of Science, PubMed, Embase, and Scopus, from the beginning of databases to January 2024. Inclusion and exclusion criteria were considered in publication screening to select qualified articles. From 328 retrieved articles, 12 articles were finally selected and included in the current systematic review and meta-analysis. Overall results showed gram-positive bacteria are the major agents of bacterial keratitis in Australian patients. Amongst the most common species, Coagulase-negative staphylococci (CoNS) strains constituted the majority of bacterial keratitis [26.1%(95%Cl:20.5-32.6)] and P. aeruginosa placed in the second rank by 13.2%(95%Cl:9-19). Furthermore, our results showed 10.9% (95%Cl:7.9-14-8) resistance to Cefalotin/Cefazolin, which had the highest prevalence, whereas the lowest resistance was to Tobramycin, which had zero. The profile of bacterial keratitis was similar to that of other countries, and in comparison with other regions, the prevalence of important species was low. Moreover, the studies from Australia confirmed the low level of resistance to antibiotics compared to other regions.