IntroductionNeonatal pustular eruptions encompass a group of disorders characterized by various forms of pustulosis occurring within the first four weeks of life. The differential diagnosis for these eruptions can be quite extensive, presenting significant diagnostic challenges even for experienced physicians. It is critical to consider potentially life-threatening conditions, such as herpes simplex virus infections, among the infectious causes. Among non-infectious entities, erythema toxicum neonatorum, transient neonatal pustular melanosis, and miliaria pustulosa are the most common.Knowing the typical and less common clinical presentation, diagnostic criteria, can aid in making the correct diagnosis and avoid unnecessary investigations and referrals.

We report a unique case of self-healing collodion baby (CB) that was successfully managed despite the risk of potentially serious complications. Self-healing CB is a rare and distinct outcome of collodion phenotype occurring in approximately 10% of the cases. The outcome depends on the initial assessment and adequate multidisciplinary approach.

Neonatal lupus erythematosus (NLE) is a rare autoimmune disease due to a passive transfer of maternal autoantibodies to the fetus. Clinical spectrum is variable and includes skin lesions, cardiac, hematological, or hepatobiliary disorders. We report a NLE case presenting with skin eruption that was initially considered as tinea.