We present the case of a 55-year old male patient who developed hyperkalemia after using Cotrimoxazole(TMP-SMX).He developed an elevated level of potassium from day-4 which kept on increasing until the drug was withheld on day-8.There was a marked increase in levels from 3.0(baseline) to 6.2 before the drug was withheld.

Immediate skin rashes,flushing,urticaria pruritus,rhinorrhea,nausea,short retching,and/or vomiting,coughing, and vertigo are symptoms of mild hypersensitivity reactions.Recognizing the type of contrast reaction is crucial to treating it.Rapid recognition of the signs and symptoms of a contrast response allows radiology personnel to quickly determine the type of reaction, allowing for faster treatment and reversal.