Hepatoblastoma, the most common liver tumor of childhood is generally treated with chemotherapy and surgery. More than half of the patients are unresectable at time of diagnosis. Therefore, neo-adjuvant chemotherapy has been the mainstay of treatment. However, long-term effects of systemic chemotherapy and inadequate response to conventional chemotherapy have been major issues in management of hepatoblastoma. As a result, attempts towards local treatment options were made such as transarterial chemoembolization (TACE) which allows tumor necrosis both via vascular occlusion and chemotherapy. Here we present a seven-year follow-up results of an infant treated with neoadjuvant chemotherapy, drug-eluting bead-TACE and surgery.

Extrarenal Wilms tumors (ERWT) are extremely rare with only isolated case reports in the pediatric literature. As there are no specific radiological findings suggesting ERWT, it is difficult to diagnose ERWT accuaretely without pathological description. We present two cases who presented with large retroperitoneal masses. Wilms tumor was not considered in differential diagnosis as the masses were located outside the kidney. An emphasize on ERWT’s clinical and surgical findings and differential diagnosis were made in this report.