Possible theoretical basis for the hypothesis of prohibition of some electron configurations in atoms and molecules presented by one of the authors earlier is considered. Existence of such prohibited configurations follows from the wave function antisymmetry of atoms and molecules. Our hypothesis is as follows: the configurations, in which the potentials of any two electrons with the same spins are equal, are forbidden. If the hypothesis comes true, it will be possible to find the nodal surfaces of many-electron wave functions for atoms and molecules analytically a priori.