Title: Simultaneity of Tuberculosis and CLL : A Case Report

Lyme Neuroborreliosis: A case reportBabak Sayad1, Arefeh Babazadeh2, Mohammad Barary3, Rezvan Hosseinzadeh4, Soheil Ebrahimpour2, Zeinab Mohseni Afshar1, *Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, IranInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IranStudent Research Committee, Virtual School of Medical Education and Management, Shahid Beheshti University of Medical Sciences, Tehran, IranStudent Research Committee, Babol University of Medical Sciences, Babol, Iran

IntroductionHuman tuberculosis (TB) is primarily caused by Mycobacterium tuberculosis. Pulmonary disease occurs in 70-90% of the patients being the most commonly affected sites. The standard therapeutic regimen for TB as recommended by World Health Organization (WHO), consists of two months of the intensive phase, and four months of the continuation phase. The intensive-phase drugs include isoniazid (H) 5 mg/kg, rifampin (R) 10 mg/kg, ethambutol (E) 15 mg/kg, and pyrazinamide (Z) 25 mg/kg. Then isoniazid and rifampin are continued for the next four months. In the cases of resistance to isoniazid, treatment with a combination of rifampin, ethambutol, pyrazinamide, and a quinolone antibiotic such as levofloxacin (Lfx) is performed for a total of six months [1-3]. Drug-induced hepatitis is the most well-known complication of anti-TB treatment. Other adverse events include anorexia, vomiting, abdominal pain, peripheral neuropathy, thrombocytopenia, renal reactions, and skin rashes [4]. Here, we reported a rare complication of levofloxacin which was used as a second-line agent for TB treatment.

Tuberculosis (TB) primarily involves the respiratory tract, but any organ in the body can be affected. In recent years, extrapulmonary TB cases have significantly increased due to the prevalence of immunocompromised patients. Here, we report a case of unilateral ankle arthritis due to Mycobacterium tuberculosis infection.