There are more and more individuals with hypertension in the globe. How to manage and self-manage hypertension with better cost-effectiveness needs economic principles and theories. Herein, in this article, the author suggests to develop a new discipline on economics and hypertension. The author briefly introduces the current status of hypertension in both China and the globe. Since lifestyle links to economics and hypertension, the author proposes that it’s about time to establish the “economics of hypertension” because it contributes to better management and self-management of hypertension not only in China but also in the globe. In fact, many clinical studies and trials have already confirmed the benefits of economic knowledge on management and self-management of hypertension. When people understand and know about related economic principles and theories, they will get more benefits from Economics of Hypertension and better protection of blood pressure with cost-effectiveness. All in all, it’s about time to establish the Economics of Hypertension, since it contributes to better management and self-management of hypertension with better cost-effectiveness. Just like Health in All Policies and Health in All Laws, Health in All Economics should be a novel consensus in the new era, particularly the COVID-19 pandemic and post-COVID-19 era.