In the present study, the course of SARS-CoV-2 natural infection in two asymptomatic cats is investigated. The source of the virus for the cats was their COVID-19-affected owner, with whom they were in continuous proximity, in a small household setting. Oropharyngeal and fecal swabs were collected to investigate the course of SARS-CoV-2 RNA concentrations, as well as the directionality of the chain