Case presentation In this case, we are presenting 26-year-old young patients, who took 60-gram metformin plus 900 mg pioglitazone, presenting with abdominal pain, nausea, confusion, and lethargy. And lactic acidosis was treated with continuous hemodialysis >15 hours. Our aim, in this case, is to highlight the importance of continuous hemodialysis in the treatment of metformin poisoning. Discussion Metformin is an oral antidiabetic drug which is used as a first line treatment in the treatment of DM. Metformin poisoning is a rare condition seen by clinicians. One of the severe side effects of metformin poisoning is lactic acidosis and it can be fatal without on-time treatment due to acidosis-related complications. Conclusion Metformin toxication is a rare condition seen in clinical practice. Metformin associated lactic acidosis is one of the expected complication. The continous dialysis can be effective to treat the lactic acidosis caused by metformin toxication. What’s already known about this topic? Lactic acidosis might be caused by metformin toxicity. Without on-time treatment for metformin toxicity, it can cause life-threatening condition. What does this article add? The treatment of hemodialysis, especially continous hemodialysis, might be beneficial to treat the patients with metformin toxicity. Key words: Metformin Toxicity, Dialysis, Lactic acidosis

Background/Aims: Gastric polyps are often detected incidentally during endoscopic procedures performed for different reasons and may sometimes be manifested by gastric bleeding, pyloric stenosis, iron deficiency anemia and abdominal pain. In our study, we aimed to investigate the demographic data of the cases who were found to have gastric polyps at the gastroenterology endoscopy unit, histologic type of the polyps, their localization and size, and their relationship with Helicobacter Pylori. Materials and Methods: Between September 2016 - September 2019, gastric polyps were detected in 255 of 9771 cases who underwent upper gastrointestinal system endoscopy at the Gastroenterology Endoscopy Unit of …….. Training and Research Hospital. Demographic data, endoscopy reports and pathology results of these patients were retrospectively reviewed from the hospital registry system. Results: Of 255 cases included in the study, 160 (62.7%) were female and 95 (37.3%) were male, with a mean age of 56.9 (min: 19, max: 95). A total of 336 polyps were detected in 255 cases, with 1.3 polyps per case. 36 (10.7%) of gastric polyps were found to be fundic gland polyps, 32 (9.5%) were found to be foveolar hyperplasia, 137 (40.8%) were found to be hyperplastic polyps, 5 (1.5%) were found to be xanthomas, and 6 (1.8%) were found to be neuroendocrine tumors. Conclusion: According to this study, 90% of gastric polyps detected endoscopically in southeast Turkey are smaller than 5 mm and located most commonly in the corpus; the most common histologic subtype is hyperplastic polyps.