Maternal diabetes insipidus does not usually adversely affect the course of pregnancy. We present a rare case of central diabetes insipidus diagnosed at 31 weeks of gestation with fetal oligohydramnios successfully treated with intranasal desmopressin. To date, only three cases of diabetes insipidus with oligohydramnios have been reported.

Phenotype of an unbalanced translocation is characterized by mutations in the translocated chromosome. We present the case of a fetus with a paternally derived unbalanced 46, XY, der(10)t(6;10)(p22;q26.1) translocation, detected following growth retardation and cardiac malformation. Our findings expand the known spectrum of unbalanced translocations for improved clinical management.