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The value of pulmonary artery acceleration time in evaluating pulmonary vascular disease in preterm infants with bronchopulmonary dysplasia Category: Original Research
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  • Liling Wang,
  • Zhijie Liu,
  • Fengjuan Zhang,
  • Haiyan Xu,
  • Haiyan Wang,
  • Xueqiang Zhao
Liling Wang
Shandong Provincial Qianfoshan Hospital

Corresponding Author:wll8787836@sina.com

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Zhijie Liu
Shandong Provincial Qianfoshan Hospital
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Fengjuan Zhang
Shandong Provincial Qianfoshan Hospital
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Haiyan Xu
Shandong Provincial Qianfoshan Hospital
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Haiyan Wang
Shandong Provincial Qianfoshan Hospital
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Xueqiang Zhao
Shandong Provincial Qianfoshan Hospital
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Abstract

Objectives— Early screening and dynamic monitoring of pulmonary vascular disease (PVD) in bronchopulmonary dysplasia (BPD) high-risk infants is of great clinical significance. Pulmonary artery acceleration time (PAAT) is a reliable and non-invasive method for assessing PVD in children over 1 year, but to date, few studies have used PAAT to assess pulmonary hemodynamics of preterm infants, especially those with BPD. Through dynamic monitoring the main hemodynamic indicators reflected PVD after birth, this study aimed to assess the value of PAAT in evaluating early PVD in BPD infants. Methods— 81 preterm infants at risk of BPD were divided into BPD and non-BPD groups according to whether BPD occurred. Clinical characteristics, PAAT, right ventricular ejection time (RVET) and other main hemodynamic indicators at 4 different time points after birth were studied and compared. Results— PAAT and PAAT/RVET increased gradually within 72 hours after birth in the BPD group ( P < 0.05), but the curve tended to be flat over time after 72 hours( P > 0.05). At PMA32 and 36 weeks, the PAAT (49.7±4.8 vs.54.8±5.7, P=0.001; 50.0±5.3 vs.57.0±5.3, P=0.001) and PAAT/RVET (0.33 ± 0.04 vs. 0.35 ± 0.03, P=0.001; 0.34 ± 0.03 vs. 0.37 ± 0.04, P = 0.001) in BPD group were significantly lower than those in the non-BPD group. Conclusions— PAAT and PAAT/RVET in the BPD group infants showed different change patterns compared to non-BPD group infants. PAAT can be used as a noninvasive and reliable screening method for screening and dynamic monitoring of PVD in BPD high-risk infants.
04 Jul 2022Submitted to Echocardiography
21 Jul 2022Submission Checks Completed
21 Jul 2022Assigned to Editor
26 Jul 2022Reviewer(s) Assigned
19 Oct 2022Review(s) Completed, Editorial Evaluation Pending
24 Oct 2022Editorial Decision: Revise Minor
14 Nov 20221st Revision Received
15 Nov 2022Submission Checks Completed
15 Nov 2022Assigned to Editor
15 Nov 2022Reviewer(s) Assigned
26 Nov 2022Review(s) Completed, Editorial Evaluation Pending
30 Nov 2022Editorial Decision: Accept