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A compendium answering over 140 questions on COVID-19 and SARS-CoV-2
  • +39
  • Pasquale Comberiati,
  • Mattia Giovannini,
  • Ioana Agache,
  • Mubeccel Akdis,
  • Magna Alves-Correia,
  • Josep Anto,
  • Alessandra Arcolaci,
  • Ahmet Azkur,
  • Dilek Azkur,
  • Burcin Beken,
  • Cristina Boccabella,
  • Jean Bousquet,
  • Heimo Breiteneder,
  • Daniela Carvalho,
  • Leticia De las Vecillas ,
  • Zuzana Diamant,
  • Ibon Eguiluz-Gracia,
  • Thomas Eiwegger,
  • Stefanie Eyerich,
  • Wytske Fokkens,
  • Ya-dong Gao,
  • Farah Hannachi,
  • Sebastian Johnston,
  • Marek Jutel,
  • Aspasia Karavelia,
  • Ludger Klimek,
  • Beatriz Moya,
  • Kari Nadeau,
  • Robin O'Hehir,
  • Liam O'Mahony,
  • Oliver Pfaar,
  • Marek Sanak,
  • Jürgen Schwarze,
  • Milena Sokolowska,
  • María José Torres,
  • Willem Van de Veen,
  • Menno van Zelm,
  • De Yun Wang,
  • Luo Zhang,
  • Rodrigo Jimenez-Saiz,
  • Cezmi Akdis
Hospital Sant Joan de Déu

Corresponding Author:criggioni@gmail.com

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Pasquale Comberiati
University of Verona
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Mattia Giovannini
Anna Meyer Chidren's University Hospital
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Ioana Agache
Transylvania University of Brasov
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Mubeccel Akdis
University of Zürich
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Magna Alves-Correia
University of Porto
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Josep Anto
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Alessandra Arcolaci
Borgo Roma Hospital
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Ahmet Azkur
Kirikkale Universitesi Veteriner Fakultesi
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Dilek Azkur
Kirikkale University Faculty of Medicine
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Burcin Beken
Trakya University Faculty of Medicine
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Cristina Boccabella
Catholic University of the Sacred Heart Rome Campus
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Jean Bousquet
Université Versailles, St-Quentin-en-Yvelines
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Heimo Breiteneder
Medical University of Vienna
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Daniela Carvalho
University of Lisbon
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Leticia De las Vecillas
Hospital Universitario Marques de Valdecilla
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Zuzana Diamant
Institute for Clinical Science, Skane University Hospital
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Ibon Eguiluz-Gracia
IBIMA-Regional University Hospital of Málaga, UMA, Malaga
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Thomas Eiwegger
The Hospital for Sick Children
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Stefanie Eyerich
Technical University and Helmholtz Center Munich
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Wytske Fokkens
University of Amsterdam
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Ya-dong Gao
Wuhan University Zhongnan Hospital
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Farah Hannachi
Hospital Centre of Luxembourg
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Sebastian Johnston
Imperial College London
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Marek Jutel
Wroclaw Medical University
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Aspasia Karavelia
General Hopsital of Chania
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Ludger Klimek
Zentrum für Rhinologie und Allergologie
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Beatriz Moya
Hospital Universitario 12 de Octubre
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Kari Nadeau
Stanford University
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Robin O'Hehir
Monash University
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Liam O'Mahony
University College Cork National University of Ireland
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Oliver Pfaar
University Hospital Marburg, Philipps-Universität Marburg, Marburg, Germany.
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Marek Sanak
Jagiellonian University Medical College
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Jürgen Schwarze
University of Edinburgh, Edinburgh
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Milena Sokolowska
Swiss Institute of Allergy and Asthma Research, University of Zurich
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María José Torres
Universidad de Málaga Facultad de Medicina
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Willem Van de Veen
University of Zurich
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Menno van Zelm
Monash University
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De Yun Wang
Yong Loo Lin School of Medicine, National University of Singapore
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Luo Zhang
Beijing TongRen Hospital, Capital Medical University,
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Rodrigo Jimenez-Saiz
National Centre for Biotechnology
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Cezmi Akdis
University of Zurich
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In December 2019, China reported the first cases of the coronavirus disease 2019 (COVID-19). This disease, caused by the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), has developed into a pandemic. To date it has resulted in ~5.6 million confirmed cases and caused 353,334 related deaths worldwide. Unequivocally, the COVID-19 pandemic is the gravest health and socio-economic crisis of our time. In this context, numerous questions have emerged in demand of basic scientific information and evidence-based medical advice on SARS-CoV-2 and COVID-19. Although the majority of the patients show a very mild, self-limiting viral respiratory disease, many clinical manifestations in severe patients are unique to COVID-19, such as severe lymphopenia and eosinopenia, extensive pneumonia, a “cytokine storm” leading to acute respiratory distress syndrome, endothelitis, thrombo-embolic complications and multiorgan failure. The epidemiologic features of COVID-19 are distinctive and have changed throughout the pandemic. Vaccine and drug development studies and clinical trials are rapidly growing at an unprecedented speed. However, basic and clinical research on COVID-19-related topics should be based on more coordinated high-quality studies. This paper answers pressing questions, formulated by young clinicians and scientists, on SARS-CoV-2, COVID-19 and allergy, focusing on the following topics: virology, immunology, diagnosis, management of patients with allergic disease and asthma, treatment, clinical trials, drug discovery, vaccine development and epidemiology. Over 140 questions were answered by experts in the field providing a comprehensive and practical overview of COVID-19 and allergic disease.
28 May 2020Submitted to Allergy
29 May 2020Submission Checks Completed
29 May 2020Assigned to Editor
29 May 2020Reviewer(s) Assigned
01 Jun 2020Review(s) Completed, Editorial Evaluation Pending
04 Jun 2020Editorial Decision: Revise Minor
05 Jun 20201st Revision Received
05 Jun 2020Submission Checks Completed
05 Jun 2020Assigned to Editor
05 Jun 2020Reviewer(s) Assigned
05 Jun 2020Review(s) Completed, Editorial Evaluation Pending
08 Jun 2020Editorial Decision: Accept