What is the impact of nonsteroidal anti-inflammatory drugs
use in symptomatic COVID-19 patients?
Fang et al .178 suggested that there is ACE2
overexpression upon treatment with ACE inhibitors, thiazolidinediones
and ibuprofen. There were concerns pertaining to the use of nonsteroidal
anti-inflammatory drugs in COVID-19 patients. The European Medicines
Agency clarified that no scientific evidence established a link between
ibuprofen, or other nonsteroidal anti-inflammatory drugs, and a risk to
worsen COVID-19.179