Introduction
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7
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1. SARS-CoV-2 virology
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7
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2. Immunology of COVID-19
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9
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2.1 B cell and antibody responses
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9
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2.2. Type 2 responses and eosinophils
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11
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2.3. T cells and lymphopenia
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12
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2.4 Immunopathology, immunosuppression and immune regulation
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14
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3. Diagnosis of COVID-19
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16
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4. Organization of allergy outpatient clinics and laboratories
during the COVID-19 pandemic
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18
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5. COVID-19 and allergic disease
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20
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5.1 Allergic rhinoconjunctivitis
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20
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5.2 Chronic rhinosinusitis and other upper respiratory tract
diseases
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21
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5.3 Asthma
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23
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5.4 Atopic dermatitis and other skin lesions
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25
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5.5 Drug hypersensitivity
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26
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5.6 Handling of allergen immunotherapy (AIT) during the COVID-19
pandemic
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26
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6. Treatment of COVID-19
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27
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7. Clinical trials and drug discovery in COVID-19
|
29
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8. Vaccine development for COVID-19
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32
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9. Epidemiology of COVID-19 and environmental factors
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33
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Conclusion
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38
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References
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50
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