Corticosteroids inhibit rhinovirus and RSV-induced
cytokine release in vitro. Do inhaled corticosteroids have a protective
effect against SARS-CoV-2?
Recent evidence indicates that inhaled corticosteroid treatment reduces
the expression of viral membrane receptors used to infect the human
airways in a dose-dependent manner.131 On the other
hand, the immune suppression exerted by corticosteroids may impair
anti-viral responses.125 However, there are no
clinical studies investigating the effect of inhaled corticosteroid on
SARS-CoV-2 infection rates.