A 14-year-old girl presented with the rapid growth of bilateral breasts within a year, causing her chest discomfort, and pressure sores in the inframammary fold. Bilateral reduction mammoplasty with free nipple-areola graft was performed. Nine kilograms of breast tissue, accounting for 15% of her total body weight, were excised.

We report the case of a 73-year-old man who was presumed to have iron deficiency anemia and was treated with iron supplements since adolescence. His workup revealed β-thalassemia minor and H63D homozygous hereditary hemochromatosis complicated with liver cirrhosis and hepatocellular carcinoma.