Objective: Assess efficacy and safety of labour induction in women with one or more previous caesarean deliveries during second and third trimester pregnancy termination or intrauterine fetal death. Design: Retrospective single-centre study between 2007 and 2018. Setting: Lille, France Population: 136 women with history of previous caesarean deliveries (CD) (study group) and 272 controls undergoing labour induction for pregnancy termination or intrauterine fetal death. Methods: Before 32 weeks, misoprostol 400 μg was given orally every 3 hours up to a maximum of five doses in 24 hours. Study group received half doses. After 32 weeks, oxytocin infusion, misoprostol (PGE1) or PGE2 (dinoprostone) were used according to the Bishop score. Main outcome measures: Vaginal delivery within the 24 hours after induction without uterine rupture or severe post-partum haemorrhage defined as blood loss > 1 litre (PPH). Results: Vaginal delivery within the 24 hours after induction without uterine rupture or PPH was 83.5% in the study group versus 92.6% in the control group (p=0.005). 5 (3.7%) uterine ruptures occurred in the study group, 1.7% in case of one previous CD and 15.8% in case of 2 or more previous CD. There were more severe PPH in the study group (6.7% versus 2.2% p=0.03), but no difference was found between women with one or more previous CD. Conclusions: Women with 2 or more prior CD should be informed that they are at higher risk of complications such as uterine rupture and severe post-partum haemorrhage.

Objective - To compare the Fetal Scalp Stimulation (FSS) to Fetal Blood Sampling (FBS) as an adjunctive test of fetal wellbeing in labor in order to reduce Fetal Blood Sampling. Design – A retrospective study from February to December 2019 Setting – Monocentric study, CHRU Lille Population - Singleton pregnancy with gestational age of more than 36 weeks, cephalic fetal presentation Methods –191 FBS procedures performed for non-reassuring fetal heart rate during labor were included. A gentle digital scalp stimulation was performed for 15 seconds, two minutes before each FBS. It was considered as positive when accelerations and/or normal variability were elicited. The FBS was classified as normal when pH was < 7.25. Results - Of the 191 FBS procedures, 163 (85.3%) found a normal pH result, 122 (63.9%) and 154 (80.6%) had an acceleration and a normal variability post-FSS, respectively. When accelerations were observed after FSS, FBS pH result was normal in 91.6% cases (95%CI, 85-95). When normal variability was observed after FSS, FBS pH result was normal in 87.4% cases (95% CI, 81-92). Conclusion - This study suggests that FSS could be an interesting alternative adjunctive test to FBS as it seems to be reliable, non-invasive and easy to perform. Thus, FSS could be performed in the first instance when non-reassuring fetal heart rate is observed in order to limit FBS only to absence of acceleration after FSS.