:Low-permeability reservoirs, characterized by their low porosity and permeability, often present significant challenges in oil and gas extraction. To enhance recovery efficiency in such reservoirs, this study examines the performance and field application of three active emulsion systems developed by Jiangsu Oilfield. Laboratory tests were conducted to assess key indicators, including emulsification performance, interfacial tension, wettability, swept pore volume, and other relevant factors. The results reveal that the S3 active emulsion delivers the best overall performance, with an interfacial tension of approximately 10 -2 mN/m, a droplet size of 0.72 μm, and the persistence of a middle-phase microemulsion layer even after 72 hours of standing. Wetting reversal was achieved at a concentration of 0.05%, promoting efficient use of small pores, making it highly suitable for low-permeability reservoir development. To validate the practical effectiveness of the S3 emulsion system, field trials were conducted in the Cui 17 block. The results demonstrated substantial improvements in oil production and water reduction, with a cumulative increase of 2,091 tons of oil and an average reduction in water cut of 13.05%, highlighting the system’s excellent field adaptability. Combining laboratory and field data, the study concludes that this active emulsion system holds significant potential for application in low-permeability reservoirs, providing valuable technical support for enhanced oil recovery in such fields.