Protein from camelina seed is a valuable co-product that can be derived from the meal remaining after oil extraction. The current study describes the types and physicochemical properties of the major proteins present in camelina meal. Seed coat mucilage, which interferes with protein extraction, was removed from whole seeds by digestion with Viscozyme® and lipids were removed with hexane to obtain demucilaged/defatted meal. Protein comprised 51.3% of meal dry matter and the eight essential amino acids comprised 40.8% of total amino acids. The meal polypeptide profile showed bands originating from cruciferin (~44.1 and 51.7 kDa), napin (~14 kDa) and oil body proteins (OBP; ~15-20 kDa) resembling that of other crucifers. Cruciferins (11 isoforms) were the predominant proteins, while vicilins (6 isoforms) also were identified among the proteins soluble at pH 8.5. Among the proteins soluble at pH 3, napins (5 isoforms) comprised the majority, though late embryogenesis abundant proteins also were found. Camelina cruciferin and napin were confirmed to possess predominantly β-sheet and α-helix secondary structures, respectively. Camelina cruciferin structure was highly sensitive to changes in medium pH and underwent acid-induced denaturation at pH 3, but exhibited high thermal stability (>80°C) at neutral and alkaline pHs. The structure of camelina napins was less sensitive to pH. The major proteins associated with oil bodies were oleosins (6 isoforms). Identification and characterization of the properties of camelina meal proteins will enable strategic paths for co-product valorization.

Objectives Endoscopic endonasal transsphenoidal adenomectomy (TSA) is the most frequently performed skull base surgery and researchers have recently focused on preserving nasal function. The transseptal approach is a promising procedure owing to its less injury to nasal mucosa. Therefore, we conducted this study to investigate whether the transseptal approach could reduce nasal morbidities with comparable neurosurgical outcomes. Study design Retrospective chart review. Setting Single-institution tertiary care centre. Participants 25 patients of transseptal approach from January 2019 to December 2020 and 25 patients of transnasal approach from January 2017 to December 2018. Main outcome measures Lund-Kennedy endoscopic scores, 22-item sinonasal outcome test (SNOT-22) scores, TIB smell identification tests (TIBSIT®) scores, the rate of gross total resection, endocrine control, and postoperative complications were collected. Results The postoperative SNOT-22 (4.40 vs. 7.36, P =.005) and Lund-Kennedy endoscopic scores (2.72 vs, 5.08 at 2 weeks, 0.88 vs. 3.52 at 1 month, 0.48 vs. 2.12 at 3 months, 0.04 vs. 1.76 at 6 months, all adjusted P < .01) were significantly lower in the transseptal group, while the TIBSIT scores were not significantly different (41.6 vs. 42.4 preoperatively, P = .68; 41.6 vs. 40.2 postoperatively, P = .46). The rates of gross total resection, recovery of hormonal abnormalities, and complications were not significantly different. In multivariate analysis, the transseptal approach remained an independent factor for lower SNOT-22 scores and Lund-Kennedy endoscopic scores. Conclusion The transseptal approach provides better recovery of nasal mucosa and intact olfactory function without compromising neurosurgical outcomes.

STUDY TITLE: Faculty Feedback NeedsAUTHORS: Parnian Pardis, Vanessa Munford, Yusuf Yilmaz, Teresa M. ChanTIME COMMITMENT FOR FIRST PHASE: The interview will run for approximately 30-60 minutes.

A six-year-old girl, living in a rural part of Sudan, suffered an accidental penetrating wound to the chest, chest X Ray showed the needle to be embedded within the heart.

Rights are not decided by science but by law and laws are made by man. However, in this scientific age it has been decided that people who are members of a minority by nature generally have the same rights as anyone else. This is known as biological essentialism. Most transgender activist do not accept this, for the sake of discussion let us accept it. Therefore, the question of transgender rights comes down to  how science answers the following questions.Do transgender people have the choice of completely conforming to gender norms and just being manly men or feminine women? Does the available data show that transgender people exist due to genetic, hormonal, neurological and or any other physical and immutable cause?Does hormone therapy for enough time or given early enough in life level the playing field for sports, and what variables effect this? What are the broader human rights implications of the answers to the above?Multiple independent studies have demonstrated a high probability that  mutations to the Androgen Receptor (AR) and estrogen receptor genes ERβ \cite{Fernandez2018} \cite{2019NatSR...920099T}These genetic differences correspond to various differences in brain strucutre such that sexually dimorphic brain structures of transwomen match those of ciswomen, and those of transmen match those of cismen. \cite{Boucher}The differences are also mannifested in the form of reduced fertility and general undermasculinization even prior to any hormone treatment. \cite{Amir2022} The above finding is backed by MULTIPLE independent expert, peer reviewed, published meta analysis, a study of all available studies. \cite{DAndrea2020}  Crucially for the issue of fairness in sports there are relevant endocrinological differences. \cite{endocsoc}A study done on post pubescent transgender adults by  \cite{Hiltona} concluded a large advantage for transgender women in every sport, however, this article was corrected by the journal due to their undisclosed confict of interest.   \cite{Hilton}A further study, also cited by Hilton as being well done, found after 1-2 years on hormones little to no difference in strength but a 5% advantage in speed for transwomen. \cite{Roberts577}Based on \cite{Roberts577} the British Journal of Sports Medicine concluded that given the data on competitors who are transitioning as young adults at the elite and collegiate levels there can be a difference that confers advantage, at the same time at the high school, youth and recreational levels when all the data is considered there is not necessarily an advantage. \cite{BJSM}Annotated Bibliography with Abstracts Findings based on Genetic research. Transgenderism is caused by mutations of the androgen and estrogen receiptor genes with effects on brain development, particularly in the basal ganglia. My Notes are in RED any emphasis is mine.Fernández, Rosa / Guillamon, Antonio / Cortés-Cortés, Joselyn / Gómez-Gil, Esther / Jácome, Amalia / Esteva, Isabel / Almaraz, MariCruz / Mora, Mireia / Aranda, Gloria / Pásaro, Eduardo Molecular basis of Gender Dysphoria: androgen and estrogen receptor interaction2018 Psychoneuroendocrinology , Vol. 98 p. 161-167 https://doi.org/10.1038/s41598-019-53500-y \cite{Fernandez2018} Abstract: Background: Polymorphisms in sex steroid receptors have been associated with transsexualism. However, published replication studies have yielded inconsistent findings, possibly because of a limited sample size and/or the heterogeneity of the transsexual population with respect to the onset of dysphoria and sexual orientation. We assessed the role of androgen receptor (AR), estrogen receptors alpha (ERα) and beta (ERβ), and aromatase (CYP19A1) in two large and homogeneous transsexual male-to-female (MtF) and female-to-male (FtM) populations.Methods: The association of each polymorphism with transsexualism was studied with a twofold subject-control analysis: in a homogeneous population of 549 early onset androphilic MtF transsexuals versus 728 male controls, and 425 gynephilic FtMs versus 599 female controls. Associations and interactions were investigated using binary logistic regression.Results: Our data show that specific allele and genotype combinations of ERβ, ERα and AR are implicated in the genetic basis of transsexualism, and that MtF gender development requires AR, which must be accompanied by ERβ . An inverse allele interaction between ERβ and AR is characteristic of the MtF population: when either of these polymorphisms is short, the other is long. ERβ and ERα are also associated with transsexualism in the FtM population although there was no interaction between the polymorphisms. Our data show that ERβ plays a key role in the typical brain differentiation of humans.Theisen, J. Graham / Sundaram, Viji / Filchak, Mary S. / Chorich, Lynn P. / Sullivan, Megan E. / Knight, James / Kim, Hyung-Goo / Layman, Lawrence C. The Use of Whole Exome Sequencing in a Cohort of Transgender Individuals to Identify Rare Genetic Variants 2019-12 Nature Scientific Reports , Vol. 9 p. 20099 https://doi.org/10.1038/s41598-019-53500-y \cite{2019NatSR...920099T}Abstract: Approximately 0.5–1.4% of natal males and 0.2–0.3% of natal females meet DSM-5 criteria for gender dysphoria, with many of these individuals self-describing as transgender men or women. Despite recent improvements both in social acceptance of transgender individuals as well as access to gender affirming therapy, progress in both areas has been hampered by poor understanding of the etiology of gender dysphoria. Prior studies have suggested a genetic contribution to gender dysphoria, but previously proposed candidate genes have not yet been verified in follow-up investigation. In this study, we expand on the topic of gender identity genomics by identifying rare variants in genes associated with sexually dimorphic brain development and exploring how they could contribute to gender dysphoria. To accomplish this, we performed whole exome sequencing on the genomic DNA of 13 transgender males and 17 transgender females. Whole exome sequencing revealed 120,582 genetic variants. After filtering, 441 variants in 421 genes remained for further consideration, including 21 nonsense, 28 frameshift, 13 splice-region, and 225 missense variants. Of these, 21 variants in 19 genes were found to have associations with previously described estrogen receptor activated pathways of sexually dimorphic brain development. These variants were confirmed by Sanger Sequencing. Our findings suggest a new avenue for investigation of genes involved in estrogen signaling pathways related to sexually dimorphic brain development and their relationship to gender dysphoria.D’Andrea, Settimio / Pallotti, Francesco / Senofonte, Giulia / Castellini, Chiara / Paoli, Donatella / Lombardo, Francesco / Lenzi, Andrea / Francavilla, Sandro / Francavilla, Felice / Barbonetti, Arcangelo Polymorphic Cytosine-Adenine-Guanine Repeat Length of Androgen Receptor Gene and Gender Incongruence in Trans Women: A Systematic Review and Meta-Analysis of Case-Control Studies 2020 The Journal Of Sexual Medicine , Vol. 17 p. 543-550 https://doi.org/10.1016/j.jsxm.2019.12.010 \cite{DAndrea2020}Abstract: Introduction: It has been hypothesized that gender incongruence in transgender women could result from an antenatal impaired androgen activity on the developing brain. As the length of polymorphic cytosine-adenine-guanine (CAG) repeat sequences in the androgen receptor (AR) gene is inversely correlated with AR transcriptional activity, some studies explored a possible association between long CAG repeats and gender incongruence in trangender women. Yet results remain inconclusive. Aim: To systematically evaluate whether a difference exists in the length of AR CAG repeat sequences between trans women and men without gender incongruence.Methods: A thorough search of Medline, Scopus, Cochrane Library, Web of Science, and CINAHL databases was carried out to identify suitable case-control studies. Methodological quality of the included articles was assessed using the Newcastle-Ottawa Scale. In the absence of between-studies heterogeneity, as assessed by the Cochrane’s Q and I2 tests, standardized mean differences (SMDs) in the length of AR CAG repeats were combined using a fixed effect model. Funnel plot and trim-and-fill analysis were used to assess publication bias.Main outcome measure: The association of gender incongruence in transgender women with longer length of AR CAG repeat sequences was evaluated by calculating pooled standardized mean difference with 95% confidence interval (CI).Results: 5 studies included in the quantitative analysis collectively provided information on 795 trans women and 1,355 control men. At the overall estimate, the MtF group exhibited a significantly longer length of AR CAG repeat sequences (pooled standardized mean difference: 0.13, 95% CI: 0.04 to 0.22; P = 0.005; I2 = 0%, Pfor heterogeneity = 0.51). Sensitivity analysis demonstrated the high stability of the result. Funnel plot revealed a possible publication bias, and the trim-and-fill test detected 2 putative missing studies. Nevertheless, the significant association persisted even when pooled estimate was adjusted for publication bias.Clinical implications: These findings could suggest a contribution of a genetically mediated impairment in androgen signaling in development of gender incongruence for transgender women.Strength & limitations: This is the first meta-analysis exploring the relationship between AR CAG repeat polymorphism and gender incongruence. However, interactions with other functional genetic variants were not explored, and caution should be exercised when generalizing these results because of the possible variability in the distribution of CAG repeats among different populations and ethnic groups.Conclusion: Trans woman population exhibits significantly longer polymorphic CAG repeat sequences in the AR gene. Further studies are warranted to elucidate whether, how and to what extent multiple functional variants in sex hormone signaling genes could be associated with gender incongruence/dysphoria.Note: Every scientific study ever has said that further studies are needed for two basic reasons. One is that science is never totally done, though it can be settled beyond any scintilla of doubt, and since performing these studies is our job, we would always like to keep doing it!Boucher, Ferdinand J. O. / Chinnah, Tudor I. Gender Dysphoria: A Review Investigating the Relationship Between Genetic Influences and Brain Development 2020 Adolescent Health, Medicine and Therapeutics , Vol. Volume 11 p. 89-99 https://doi.org/10.2147/ahmt.s259168 \cite{Boucher}Abstract: Gender dysphoria (GD) is a facet of modern human biology which is believed to be derived from the sexual differentiation of the brain. GD “involves a conflict between a person’s physical or assigned gender and the gender with which he/she/they identify”, as defined in the DSM-5. Individuals report feeling uncomfortable and faced with prejudice from those around them, affecting their mental health. Elucidating the relationship between genetic influences on gonadal and brain development could give an insight into understanding this clinical condition. To explore this issue, a review of the literature database was carried out. Evidence suggests that abnormal biological processes, including mutations in certain genes, can lead to abnormal gonadal development, causing some fetuses to present with indifferent gonads and to be reassigned at birth to the default female sex. This disparity in genetic influences relates to an increased likelihood of a diagnosis of GD. An investigation into complete androgen insensitivity syndrome, involving androgen receptor (AR) gene mutation, suggests that such individuals also experience GD. It is known that the brains of males and females are different. Evidence further suggests that brain anatomy and neuronal signaling pathways are more closely aligned with a person’s perceived gender identity. Individuals who present with discordant gonadal and brain developments experience psychological challenges that may contribute to a state of unease or generalized dissatisfaction with their biological sex. These point to a possible biological and genetic underpinning of GD as stemming from a discordance between gonadal and brain development. However, not enough evidence has associated these differences with GD. Further research is required to elucidate the true mechanisms and possible inheritance pattern of GD for a better education and greater understanding by clinicians and the general public on perceptions regarding GD.

Transcatheter aortic valve implantation (TAVI) is rapidly spreading across the world with the endorsement of the cardiological community(1) and the supporting results of randomised controlled trials (2,3). However, TAVI-related complication like aortic dissection, aortic valvular rupture, or left ventricle perforation are still potentially catastrophic (4).

This report describes the case of an 84-year-old male who was brought to the emergency room because a dental bur was swallowed accidentally during a dental procedure. The foreign body was successfully removed by gastroenterologists endoscopically 8 days after the ingestion and was identified as a 2-cm-long dental bur.

Neuroendocrine tumors have a wide range of malignant potential. These tumors infrequently metastasize to the orbit. We report the case of a 61-year-old man who presented with unilateral recurrent panuveitis related to choroidal metastasis. Explorations led to the diagnosis of pancreatic neuroendocrine carcinoma as the primary tumor.

A 77-year-old female patient was taken to surgery for correction of complete rectal prolapse. On the first postoperative day the patient presented severe generalized abdominal pain, with no other symptoms. l. An abdominal CT scan was performed, which showed pneumoperitoneum and air near the coloanal anastomosis

Background: Dysregulation of the arachidonic acid metabolic pathway is the most widely known pathomechanism of AERD. We performed integrative analysis of transcriptomic and epigenomic profiling with network analysis to determine the novel pathogenic features of AERD. Methods: Ten patients with asthma including 5 patients with AERD and another 5 patients with aspirin tolerant asthma (ATA) were enrolled. Nasal epithelial scraping was performed and nasal mucosa was used in omics profiling. Peripheral eosinophil counts, sputum eosinophil counts, FeNO levels, and pulmonary function test results were evaluated. Differentially expressed genes (DEGs), differentially methylated probes (DMPs) and differentially correlated genes (DCGs) between patients with AERD and those with ATA were analyzed. Network analysis using Ingenuity Pathway Analysis (IPA) was performed to determine the gene connection network and signaling pathways. Results: In total, 1,736 DEGs and 1,401 DMPs were identified. Finally, 19 pairs for DCGs were selected. Among DCGs, genes related to vesicle transport (e.g. STX2 and RAB3B) and sphingolipid dysregulation (e.g. SMPD3) were found to be hypo-methylated and up-regulated in patients with AERD. A total number of 78 asthma-related DEGs were identified by the IPA knowledge base. Using the canonical pathway analysis of IPA, signaling pathways of T helper cell differentiation/activation and Fcε receptor I were generated. Up-regulation of RORγt and down-regulation of MHCII, TNFR, and TGF-β as well as up-regulation of FCER1A and JAK and down-regulation of VAV and cPLA2 were noted in patients with AERD. Conclusions: Distinct pathogenic features were identified by using integrative multi-omics data analysis in patients with AERD.

Introduction: Point of care ultrasound (POCUS) is a useful tool to determine endotracheal tube placement; however, few studies have compared it with standard methods of confirmation. We evaluated the diagnostic accuracy of POCUS and time-to-interpretation for correct identification of tracheal versus esophageal intubations compared to a composite of standard-of-care methods in neonates. Methods: A cross-sectional study was conducted in the Neonatal Intensive Care Unit (NICU) at Aga Khan University Hospital Karachi Pakistan. All required intubations were performed as per NICU guidelines. The ETT placement was determined using standard-of-care methods (auscultation, colorimetric capnography, and chest X-ray) by a clinical team, and simultaneously by POCUS. Timings were recorded for each method by independent study staff. Results: A total of 348 neonates were enrolled in the study. More than half (58%) of intubations were in an emergency scenario. Using an expert as the reference standard, POCUS user interpretation showed 100% sensitivity and 94% specificity. We found a 99.4% agreement (Kappa: 0.96; p<0.001) between the POCUS user and expert. Diagnostic accuracy of POCUS compared with at least two standard-of-care methods demonstrated 99.7% sensitivity, 91% specificity, and 98.9% agreement (Kappa:0.93; p<0.001). The median time required for POCUS interpretation was 3.0 (IQR 3.0 -4.0) seconds for tracheal intubation. The time recorded for auscultation and capnography was 6.0 (IQR 5.0 -7.0) and 3.0 (IQR 3.0-4.0) respectively. Conclusion: POCUS is a rapid and reliable method of identifying ETT placement in neonates. Early and correct identification of airway management is critical to save lives and prevent mortality and morbidity.

Spontaneous bilateral intra-orbital hematoma is a rare complication of sickle cell disease in children. Imaging examinations are of paramount importance in the diagnosis and condition the management in order to avoid complications that can compromise the visual function prognosis.

Introduction: The reliability of breath sound analysis using an improved method in infants has been reported. Objective: Breath sounds of infants with respiratory syncytial virus (RSV)-induced acute bronchiolitis were analyzed to evaluate their specificity and examine their relationship with the severity. Subjects and methods: We evaluated the inspiratory and expiratory breath sound parameters of 33 infants (median age=2 months old) diagnosed with RSV-induced acute bronchiolitis. The sound powers of inspiration and expiration and the spectrum curve indices (ratio of the third and fourth area to the total area under the curve and ratio of the power and frequency at 50% and 75% of the highest frequency were evaluated at the acute phase and recovery phase. Furthermore, the relationship between the breath sound parameters and the clinical severity of acute bronchiolitis was examined. Results: Analyses of the breath sound spectrogram showed that the power of expiration at the acute phase was large, and was the expiration-to-inspiration sound power ratio in a mid-frequency range (E/I MF), with values decreased in the recovery phase. Data of the inspiratory sound spectrum curve showed the improvement of airway stenosis during the recovery period. Furthermore, there were significant relationships between the E/I MF and SpO2 and the severity score of acute bronchiolitis. Conclusion: In RSV-induced acute bronchiolitis, specificity of breath sounds was observed in the expiration sound and the reversible airway stenosis was evaluated. Breath sound analyses are expected to be useful for the diagnosis and clinical evaluation of the severity of acute bronchiolitis.

La presenza di contaminanti emergenti (ECs) nell’ambiente rappresenta un aspetto critico a causa dei potenziali impatti negativi che questi contaminanti possono causare minacciando la qualità degli ecosistemi e la salute umana. Sebbene siano presenti a bassi livelli di concentrazione nell’ambiente, gli ECs sollevano grande preoccupazione a causa dei potenziali effetti tossicologici sugli organismi viventi, della capacità di favorire il fenomeno dell’antibiotico resistenza e della scarsa biodegradabilità che ne comporta l’accumulo nell’ambiente con conseguente possibilità di arrivare all’uomo tramite la catena alimentare. Gli impianti di trattamento delle acque reflue (WWTP) rappresentano una possibile fonte di diffusione di ECs nell'ambiente poiché i convenzionali processi di trattamento non ne garantiscono una rimozione efficiente. Di conseguenza, l'integrazione di processi di trattamento avanzata nei WWTP risulta essenziale per rimuovere i contaminanti emergenti prima dello scarico o del riutilizzo dell’effluente trattato. Il processo USAMe® e l’integrazione di processi elettrochimici in sistemi di filtrazione (e-MBR, e-SFDMBR) sono esempi di tecnologie innovative per la rimozione di contaminanti emergenti dalle acque reflue.

For rare conditions, avoiding hastily publishing case reports, conducting a thorough literature search, and ensuring the patient’s presentation aligns with accepted diagnostic criteria are each essential. Failure to heed the above can lead to serious inaccuracies, as illustrated by four articles we reviewed in the past year.

Environmental considerations are among the main reasons for selecting fuel cells as a strategic approach. To conduct a feasibility study for the application of a combined system in residential buildings for thermal energy (heat) and electricity (power) production, this paper comprehensively investigated the use of polymer fuel cells and solar energy in Farabi Administrative-Educational Building in the Islamic Azad University, Hamedan Branch, Iran. This educational building is located in the cold arid climate of Hamadan, which is a high-altitude city, and its working hours coincide with solar radiation hours. The use of electricity produced by photovoltaic (PV) panels for hydrogen generation is a new effort to use solar energy in classrooms. Attempts were made to produce the fuel used in polymer fuel cells, i.e., hydrogen, by a polymer electrolyzer and solar energy with the objective of supplying electricity to Farabi Building with the highest cost-effectiveness. Part of thermal energy is supplied by heat removed from the fuel cell. The process was analyzed with the help of TRNSYS energy processor. According to the results, 4923 kW electricity is obtained by installing the designed system, reducing carbon dioxide production by 5662200 g on average.

Tillage practices can influence soil microbial carbon use efficiency (CUE), which is critical for carbon cycling in terrestrial ecosystems. The effect of tillage practices could also be regulated by nitrogen (N) addition. However, the soil microbial mechanism about N fertilizer effect on microbial CUE under no-tillage is still unclear. We investigated how N fertilizer regulates the effect of tillage management on microbial CUE through changing microbial properties and further assessed the impact of microbial CUE on particulate (POC) and mineral-associated organic matter carbon (MAOC) using a 16-yr field experiment with no-tillage (NT) and conventional tillage (CT), both of which combined with 105 (N1), 180 (N2), and 210 kg N ha-1 (N3) N application. We found that microbial CUE increased with increasing N application rate. NT increased microbial CUE compared with CT under N1. The bacterial and fungal diversities of NT was higher than CT and N application decreased their diversities in the 0-10 cm layer. The partial least squares path model showed that bacteria diversity, fungal diversity, and fungal community structure played more critical roles in increasing microbial CUE. Furthermore, POC and MAOC under NT were higher than CT and they also increased with increasing N application rate. This could be explained by the finding that increasing microbial CUE induced by N application had the potential to increase POC and MAOC. Overall, N addition is an important pathway to influence microbial CUE, which is mainly regulated by bacterial and fungal diversities rather than their biomass under no-tillage.

The paper overviews and summarizes the results of the developing a methodology for the land degradation neutrality (LDN) assessment basing on LDN-based studies at national, regional and local levels in Russia. The review of more one hundred available publications in Russian language over the past 6-7 years allowed for analysis on the following areas: development of LDN terminology, LDN assessment at the different levels, adapting transition matrix; application of global and national LDN indicators; using the LDN concept for economic valuation of land, estimating LDN baseline, and using LDN as an integral indicator for sustainable land management. With the LDN concept the issue of land degradation (LD) has gone beyond the limited scope of desertification and drylands, and enlarged the concept of “rational” or “effective” land use and land management dominated in Russia. The LDN concept has been broadened with the introduction of the LDN Index proposed to evaluate the rate of LDN achievement; proposal on reconstructing transition matrices and adding specific land cover sub-categories; approach of integrating traditional national sectoral systems for assessing land quality with an LDN add-on; justification for using additional and specific LDN indicators at national and subnational level (soil erosion, aridity, soil salinity, soil depletion, etc.); importance of factoring natural background trends like climate change, natural succession cycles linked with geological and geomorphological processes; need for using different site-specific LDN baselines, not only those time-based; approaches for LDN-based economic valuation of lands; and the LDN-based typology of SLM practices and models.

Right atrial appendage aneurysms (RAAAs) are extremely rare in cardiac anomaly. According to the literature, no more than 25 cases have been reported so far, among which only 3 cases were children. Here, we reported an infant with a giant RAAA and severe symptoms. The RAAA was diagnosed by echocardiography and surgically resected under cardiopulmonary bypass. The role of transesophageal echocardiography was very important during the aneurysm resection surgery, which helped surgeons to plan surgical procedures during the surgery and evaluate the surgical effect postoperatively.

In this paper, we consider the equations of motion of a bar, of a given density, infinite in both direction, undergoing longitudinal vibrations under the action of an external load, and a stress-strain relationship using a fractional order differentiation operator with respect to the time variable. We use three types of fractional operators, two non-singular, one with exponential kernel and Mittag-Leffler type kernel. And a singular one with power-law type kernel. We analyze some initial and boundary value problems resulting from the modeling of the aforementioned wave processes in viscoelastic media, using some recent proposals for fractional order derivatives. The fundamental solution of these problems is established, and its moments are calculated.

In this study we consider the inverse problem of determining the nonlinear right-hand side of a quasi-linear parabolic equation and prove a uniqueness theorem. Stability estimate for the solution are obtained. A method of representing the nonlinear right-hand side explicitly is proposed for the special case.

The internal structure of packed beds formed by different arrangements of packings has been a subject of study for the past several decades. In this study, we have attempted to investigate the structure formed in laboratory-scale packed beds through experimentation and modeling, employing different ways of packing the bed. The structure has been measured using Micro-Computed Tomography (Micro-CT) and characterized through appropriate metrics. The “filling of the bed” has been modeled using a technique called Collision Guided Packing (CGP). Thus, this contribution combines both high resolution measurements as well as detailed particle-based models, bringing out a head-to-head comparison of the bed filling process and also how the final bed is configured (its structure). The work stands as an independent piece, but also provides the basis for a rigorous understanding of the impact of bed filling on deep hydroprocessing, wherein the bed structure is known to have a dramatic effect.

We studied the thermomechanical and microstructural properties of oleogels developed with 2.1 to 15.7 Moles of monoglycerides/Mole of lecithin (MG/LC). The oleogels were developed (15°C) in vegetable (VO) and mineral (MO) oils using at each MG/LC 2% or 4% total mass of gelator. During oleogelation a synergistic MG-LC interaction existed deriving in the development of MG-LC cocrystals even below the gelators’ minimum gelling concentration. The cocrystals delayed the Lα→β polymorphic transition and worked as an active filler of the oleogels’ crystal network. In the VO, the oil with the highest relative polarity, the oleogels were structured by a network of β crystals where the cocrystals acted as an active filler. In the MO, the oil with the lowest relative polarity, the cocrystals’ development was favored while the Lα→β transition occurred just in the 15.7 MG/LC oleogels. Then, at all MG/LC the VO oleogels with 2% or 4% total gelator concentration achieved higher G’ than MO oleogels. However, the presence of β crystals will produce deleterious effects in shorter time in the VO oleogels than in the MO oleogels. In both oils the oleogels with the highest G’ and gel-like rheological behavior were achieved at 8.1 MG/LC, particularly at 4% total gelator concentration. Under these conditions the β polymorph was limited developed in the VO oleogels and completely absent in the MO oleogels. Then, we might tailoring the rheology of MG-LC oleogels with storage stability using as design variables the MG/LC, the total gelator concentration, and the polarity of the oil.

Sensitization to shrimp and house dust mites in a Swedish population-based study: Influence on allergic disorders and lung functionIda Waern1, Magnus Molin2, Robert Movérare2,3, Jonas Lidholm2, Andrei Malinovschi4, Magnus P. Borres2,5, Christer Janson3.1Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden2Thermo Fisher Scientific, Uppsala, Sweden3Department of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden4Department of Medical Sciences: Clinical Physiology, Uppsala University, Uppsala, Sweden5Department of Maternal and Child Health, Uppsala University, Uppsala, Sweden