This paper deals with an axially moving viscoelastic beam with a boundary non- linear term. Our purpose is to extend the class of the relaxation functions Z that guaranteeing a general deacy. For this, we consider the following general condition Z′() ≤ -(t)(Z(t)) where is an increasing and convex function and is a non- increasing function on the whole ℝ+,This type of functions was developed by Conti and Pata in 6 and improved by Kelleche and Feng in 11. The obtained result improves the previous ones12,13.

Introduction The COVID-19 pandemic has severely impacted theatre utilization and patient care in cardiac surgery. This study assesses impact on theatre utilisation efficiency and cardiac care pathway during Covid compared to preCovid period. Method OR data for preCOVID period (1st Jan to 23rd Mar 2020) for major cardiac cases were compared to COVID period for predefined indices of OR utilisation and efficiency. Categorical variables were compared with Chi-squared and continuous variables with Man Whitney U test. P value<0.05 was considered significant. Results Total 363 surgeries were logged (304; preCovid, 59; COVID). There was significant reduction in cases/day (median 5 cases/day preCovid to 1 case/day during Covid, p<0.001). OR utilization capacity was less than 50% for 36/65 (55.4%) Covid days versus 5/59 (8.5%) preCovid days (p<0.001). Almost half the Covid days (43.1%) had no operations. Patients during Covid were younger (median 62 years vs 69 years, p<0.01) but higher risk (logEuroscore 6.6 vs 4.7, p<0.01). Index of operational efficiency (InOE) remained unchanged (preCovid;78.8% vs COVID;79%, p=0.90). Covid adversely affected Surgical efficiency (preCovid;74% vs COVID; 68.5%, p<0.001). Conclusion There was significantly decreased workflow due to reprioritization of resources. Operational service could be delivered to high efficiency despite significant changes in patient care pathways.

To explore the phylogeography of Rattus tanezumi and Rattus norvegicus in China, 486 individuals collected from 31 localities were initially analyzed with mitochondrial DNA and 10 microsatellite loci. Then, 123 individuals from 18 localities were subjected to 2b-RAD analyses. There were several major findings. Although R. norvegicus is widely distributed in China, R. tanezumi is mainly distributed in southern China, but is currently invading northward and has occupied many regions of northern China. Development of shipping transportation in ancient China had an important role in expansion of these two species; except for westward and southward colonization by land, some individuals of R. norvegicus reached the southeast coast of China by shipping transportation and subsequently expanded to central China; R. tanezumi immigrated to the southeast coast of China from Southeast Asia, and then expanded to central and western China. Before large-scale expansion associated with human transportation, changes in Ne of these species were closely related to climate changes. However, after immigration of R. tanezumi into China, interspecies’ competition may have had a great role in their population sizes, as the R. norvegicus population declined rapidly with the increase of Ne for R. tanezumi. Analyses with 2b-RAD sequences did not support interspecies hybridization, although microsatellite data indicated potential gene introgression. Our study provided a valuable framework for further investigations on the expansion of the two dominant rat species in China. Finally, results also indicated that previous investigations on hybridization based solely on microsatellite data should be verified with genomic SNP data.

The multiple-input multiple-output (MIMO) dual-function radar-communication system can adjust the sidelobe level (SLL) by transmit beamforming to realize the communication function in the line-of-sight channel. However, a high SLL of the transmit beampattern can affect target detection performance. We propose a low-sidelobe covariance matrix design of transmit waveform method to address this issue. Minimizing the integrated sidelobe level is taken as the objective function with the constraint of the mainlobe lower and upper bounds. The optimal global solution can be obtained by the interior point algorithm since the objective function is semi-definite programming. Finally, the simulation results verify the performance in transmit beampattern and bit error rate.

The effective identification of series arc faults is of great significance for preventing fires in residential buildings. Considering the disadvantage that the fault features of the current signal are hidden deeply and different correlation features and irrelevant features are mixed in the current signal, which makes the training speed of the learning algorithm slow and the recognition accuracy low, this work proposes a method based on complete ensemble empirical mode decomposition with adaptive noise (CEEMDAN) decomposition and convolutional neural network (CNN). The CEEMDAN algorithm is used to decompose the collected current signals. Then the IMF components with no representational significance are eliminated by calculating the spearman correlation coefficient before being fed into the CNN. We select five different electric loads for experimental validation with various signal characteristics, including heaters, induction cooktops, computers, microwave ovens and vacuum cleaners. The experimental results show that the proposed method has an accuracy rate of 95.23%. Therefore, it can be used for serial fault arc recognition in residential building power distribution systems.

A document by Pungkava Sricharoen. Click on the document to view its contents.

Objective: To discern the optimal plan for delivery in nulliparous women with obesity at term gestation. Design: Large population-based retrospective cohort study Setting: Maternity hospitals in Ontario, Canada Population: Nulliparous women with obesity (BMI>30) with live, singleton, uncomplicated term gestations (37+0 to 41+6 weeks) between April 1st, 2012 and March 31st, 2019 Methods: Women were divided by plan for delivery (expectant management, induction of labour and no-labour caesarean section). The outcomes of interest were adverse delivery outcomes. Analyses were conducted using multivariable regression models. Analyses were stratified by each week of gestational age and by obesity class. Main Outcome Measures: The primary outcome was the Adverse Outcome Index (AOI), a binary composite of 10 maternal and neonatal adverse events. The Weighted Adverse Outcome Score (WAOS) was the secondary outcome. It provides a weighted score of each adverse event included in the AOI. Results: No-labour caesarean section reduced the risk of adverse delivery outcome by 41% (aRR 0.59, 95%CI [0.50, 0.70]) compared to expectant management at term gestation. There was no statistically significant difference in adverse birth outcomes when comparing induction of labour to expectant management (aRR 1.03, 95% CI [0.96, 1.10]). The greatest benefit to no-labour caesarean section was observed in the reduction of adverse neonatal events (aRR 0.70, 95% CI [0.57, 0.87]) particularly at 39 weeks of gestation. Conclusion: In women with obesity, no-labour caesarean section reduces adverse birth outcomes. Funding: Canadian Institute for Health Research (CIHR) (#MFM146444). Keywords: Plan for delivery, Induction of Labour, Caesarean Section, Obesity

Objective: To determine the natural salicylic acid levels in normotension and preeclampsia who were not taking Acetylsalicylic Acid Design: A case-control study Setting: A university medical center Population: A case-control study of 148 pregnant women divided into four groups: normotension 20-34 weeks (n=35), normotension >34 - 40 weeks (n=39), early-onset preeclampsia (n=35), and late-onset preeclampsia (n=39). Method: The four groups were matched at a ratio of 1:1 concerning a gestational week. Socio-demographic characteristics and reproductive history were compared among the four groups. The numeric data were checked for normal distribution using the Kolmogorov Smirnov test, presented as mean ± SD if normally distributed and as median (IQR) if not normally distributed, Kruskal Wallis test was used to identify significances among groups and performed with Mann Whitney test. Result: Serum SUA level in EOP were significantly different from normotension with median 1.43 μmol/L (min-max 0.001-9.32) versus 0.21 μmol/L (0.002-15.78) (p<0.05), albumin in EOP significantly lower from normotension, median 3 gr/dl (2.1-3.8) vs 3.7 gr/dl (3.4-4.3) (p<0.05), and protein intake significantly lower than normotension (13% vs 14%, p<0,05) and correlates with SUA serum (r -0.572).There was no significant difference of SA and SUA in LOP and normotension, albumin level on LOP significantly lower with median 3 gr/dl vs 3.4 gr/dl(p<0.05). Conclusion: There was no significant difference in salicylic acid and salicyluric acid levels in serum and urine in preeclampsia and normotension. The serum SUA levels in the EOP group were greater and associated with low albumin levels and low protein intake.

Esse conteúdo digital foi criado como parte da atividade de capacitação ”Introdução ao R e RStudio para ciência social computacional”. É uma iniciativa de formação e difusão científica do Observatório de Populações e Políticas Púbicas (ObPPP) e do Programa de Formação Complementar de Graduação em Pesquisa Social Computacional (InfoSoc), ambos vinculados ao Dept.º C. Soc. / CLCH, Universidade Estadual de Londrina (UEL), Paraná - Brasil

A patient with stage IV uterine cancer displaying circulating tumor cells and high microsatellite instability who had rejected standard chemotherapy and immune-check-point inhibitor treatment received monotherapy with autologous formalin-fixed tumor vaccine (AFTV). The treatment resulted in shrinkage of multiple lung metastases, suggesting that AFTV will be an attractive treatment option.

Sustainability of agroecosystems is the most challenging task for humans in this anthropocentric era. The faulty agriculture practices and several undesirable anthropological factors caused substantial soil erosion, desertification, and soil dryness, resulting in a severe decline in soil biodiversity and crop productivity. The mismanagement of agriculture land has deteriorated around 25% of the world’s total land area, resulting in the annual loss of approximately 24 billion tonnes of soil. By 2050, 95% world’s land might be degraded if current trends continue. The tillage practices are responsible for more than 150 t ha -1 of annual soil loss around the world. Soil erosion is responsible for 40% of all soil deterioration worldwide. Agricultural land degradation is mainly caused by intensive soil ploughing, removal or burning of crop leftovers, poor pasture management, and insufficient crop rotations. Conservation Agriculture (CA) practices are essential for soil quality restoration and improvement. The global annual adoption rate of CA has been 7 M ha year -1 over the last ten years. By decreasing soil erosion, maintaining soil structure, and encouraging soil organisms, by using CA practices, Brazil has stored around 12 million tonnes of carbon from 23.6 M ha of land. The regenerative CA practices are also important to the achievement the sustainable development goals (SDGs). This review seeks to gather and provide collective literature on the global agroecosystem situation and the impact of CA methods in restoring our degraded agroecosystems for food security.

The current mainstream dietary pattern analysis methods including data-driven and investigator-driven methods have their own limitations.Our goal is to develop a hybrid method to establish the relationship between the intake of various nutrients and the quality of the Chinese diet using machine learning methods. We employed the Chinese Health Eating Index (CHEI) as a apriori expertise to evaluate the diet quality of Chinese people and designed a scheme to predict the CHEI score with nutritional ingredients using machine learning methods. Based on the diet records of 28,000 respondents in the CHNS dataset, seven machine learning regression models were evaluated, and the Gradient Boosting model achieved the best R2 score (0.86). In addition, through separate verification experiments, we found the performance of the proposed method was stable among different population subgroups and the predicted result was reliable.

This paper presents innovative series and summations derived from the optimized combinations relating to the combinatorics. These series and summations will be useful for the researchers who are involving to solve the scientific problems.

The vegetation restoration is very important for the stability of the ecological system structure and function in the loess region of North Shaanxi Province. Natural restoration and artificial restoration are the two primary modes for vegetation recovery and soil quality improvement in this region. In this study, two adjacent watersheds with similar ecological environment conditions but different restoration modes were selected for research; and one watershed adopted natural restoration (He Gou watershed) and the other adopted artificial restoration (Chai Gou watershed). According to the study of soil stoichiometric characteristics and soil quality after the vegetation restoration in these two watersheds, the results showed: (1) Compared with the natural restoration, artificial restoration was more effective in increasing the content of SOC and TN, but insignificantly effective in increasing the content of TP. (2) The ratios of soil C:N, C:P and N:P showed a decreasing trend with the soil depth increased at these two restoration modes. (3) in the 0 -60 cm soil layer, the soil quality using the artificial restoration mode was better than the natural restoration, especially for the soil layer beneath 20 cm. (4) The minimal data set on the soil quality evaluation in the study area included 5 indicators including SOC, CWHC, AK, SWC and AP. The minimal data set showed a linear relation with the total index data set (y=0.829x+0.058，R 2=0.76) and the minimal data set can reflect the soil quality more sensitively than the total indicators data set.

Mycoplasma (M.) pneumoniae is a common pathogen causing respiratory infections in children. Pulmonary embolism is a rare complication that may be life-threatening if not diagnosed early and treated promptly. Here, we report the case of an 11-year-old patient with pulmonary embolism associated with M. pneumoniae pneumonia. The patient developed uncorrectable hypoxemia and received venovenous extracorporeal membrane oxygenation treatment. Although the mechanism of thrombosis after M. pneumoniae infection remains unknown, an increase in the cold agglutinin titer indicates that cold agglutinin syndrome might be the mechanism of this pathological change. Finally, the patient was cured with antibiotic and anticoagulant therapies. Patients who have significantly increased C-reactive protein and D-dimer levels and positive cold agglutinin after M. pneumoniae infection should be monitored for the possibility of thrombosis formation.

Despite the recognized role of wild waterfowl in the potential dispersal and transmission of highly pathogenic avian influenza (HPAI) virus, little is known about how infection affects these birds. This lack of information limits our ability to estimate viral spread in the event of an HPAI outbreak, thereby limiting our abilities to estimate and communicate risk. Here we present telemetry data from a wild Lesser Scaup ( Aythya affinis), captured during a separate ecology study in the Chesapeake Bay, Maryland. This bird tested positive for infection with clade 2.3.4.4 HPAI virus of the A/goose/Guangdong/1/1996 (Gs/GD) H5N1 lineage (results received post-release) during the 2021-22 ongoing outbreaks in North America. While the infected bird was somewhat lighter than other adult males surgically implanted with transmitters (790g, mean=868g, n=11), it showed no clinical signs of infection at capture, during surgery, nor upon release. The bird died 3d later, pathology undetermined as the specimen was not able to be recovered. Analysis of movement data within the 3d window showed that the infected individual’s maximum and average hourly movements (3894.3m, 428.8m respectively) were noticeably lower than noninfected conspecifics tagged and released the same day (mean =21594.5m, mean =1097.9m, respectively; n=4). We identified four instances where the infected bird had direct contact (fixes located within 25m and 15 min) with another marked bird during this time. Collectively, these data suggest that the HPAI positive bird observed in this study may have been shedding virus for some period prior to death, with opportunities for direct bird to bird or environmental transmission. Although limited by low sample size and proximity to the time of tagging, we hope that these data will provide useful information as managers continue to respond to this ongoing outbreak event.

The spread of COVID-19 and the worldwide implementation of restrictive measures for the containment of SARS-CoV-2 led to drastic population behavioural changes. The aim of this review is to summarize the behavioural changes observed in asthmatic children during this period, present the concurrent changes in childhood asthma morbidity and discuss possible implications of these observations for public health and clinical practice in the post-COVID-19 era. Studies published from November 2021 to February 2022 were identified from PubMed® and Google Scholar databases using appropriate search terms. Numerous studies have assessed the morbidity of children with asthma during lockdown periods and associated these changes with reduced exposure to environmental triggers and respiratory viral infections, while a lockdown-independent increase in patient compliance to treatment was also observed. Within this context, asthmatic children demonstrated reduced asthma-related emergency department visits, less usage of systemic steroids and in general an improved disease control, with some data suggesting a positive association of asthma control and lockdown stringency. In summary, this narrative review examines the behavioural changes brought by lockdowns, their cumulative beneficial effect on paediatric asthmatic morbidity, and triggers a debate on how public health measures may be taken to benefit children with asthma in a post-COVID-19 era.

Objective(s): To determine the impact of Clostridioides difficile Infection (CDI) among pediatric Cystic Fibrosis (CF) hospitalizations using a large nationally representative pediatric hospital database . Study design: We identified Cystic Fibrosis-related hospitalizations during the years 1997 to 2016 in the Kids’ Inpatient Database [KID] and compared in-hospital mortality, Length of Stay [LOS], and hospital charges among hospitalizations with and without a coexisting diagnosis of C. difficile using logistic regression models for mortality and general linear models with gamma distribution and logarithmic transformation for LOS and hospital charges. We also evaluated temporal trends in the proportion of CF hospitalizations with concomitant CDI using data published triennially Results: We analyzed 21, 616 pediatric CF hospitalizations between the years 1997 to 2016 and found a total of 240 (1.1%) hospitalizations with concurrent CDI diagnosis. Adjusted analyses demonstrated an association of CDI with increased mortality (OR 5.2, 95% 95% CI 2.5-10.7), longer LOS (46.5% increment, 95% CI 36.0-57.1), and higher charges (65.8% increment, 95% CI 53.5-78.1) for all comparisons. The proportion of CF hospitalizations with CDI increased over time from 0.64% in 1997 to 1.73% in 2016 (p<0.001). Conclusion(s): As CDI is associated with excess mortality, LOS, and cost in children hospitalized for CF, efforts to reduce infection rates and aggressive diagnosis and treatment of active infections should be prioritized to improve hospital outcomes among children with CF.

COVID-19 is known to cause hypercoagulable and pro-inflammatory states and increase the risk of cardiovascular events. We present a case of a 57-year-old female with prior COVID who subsequently developed a STEMI requiring LVAD due to new-onset heart failure. There are no similar reports of this cardiovascular complication in COVID-19.

Background Symptoms and associated distress in children diagnosed and treated for cancer are uniformly common, yet structured and systematic symptom monitoring is not yet commonplace. With increasing pressures on the healthcare workforce, improved systematic approaches to symptom management are required. Methods Medical, nursing and allied health oncology clinicians developed algorithms using consensus techniques to ascertain thresholds of concern for each symptom for the Symptom Screening in Pediatrics (SPPedi) tool, a Patient Reported Outcome Measure (PROM). Algorithm vetting and refinement were achieved through iterative interviews and consultation with clinicians. Self-management evidence-based recommendations for each symptom were developed. The algorithms were incorporated into an existing smartphone application (MyQCH), as part of the Oncology Hub, and an iterative evaluation is planned to test the feasibility, acceptability, safety, usefulness, and other domains including a hybrid effectiveness trial (ACTRN12621001084875). Discussion Digital solutions provide alternative options for communication, information, and education and opportunities to harness the best of community and hospital services. The Oncology Hub and RESPONSE system is a comprehensive approach to symptom management that includes a suite of tools and resources including a smartphone app that collects PROMs and delivers symptom management advice, as well as written resources for both the families of children with cancer and clinicians. Conclusions Using technology offers new ways to think about how clinicians and families communicate and share information. Understanding how information is exchanged using technology, and how this impacts clinical workflow is critical to successful implementation, and to ultimately optimise symptom assessment management in children with cancer.

Most Species Distribution Models include spatial effects to improve prediction at unsampled locations and reduce Type I errors. Ecologists tend to try ecologically interpret the spatial patterns displayed by the spatial effect. However, spatial autocorrelation may be driven by many different unaccounted drivers, which complicates the ecological interpretation of fitted spatial effects. This study wants to provide a practical demonstration that spatial effects are able to smooth the effect of multiple unaccounted drivers. To do so we use a simulation study that fit model-based spatial models using both geostatistics and 2D smoothing splines. Results show that fitted spatial effects resemble the sum of the unaccounted covariate surface(s) in each model.

Nonobstructive Hypertrophic Cardiomyopathy with preserved EF is a well-known ejection fraction preserved heart failure and oral medical therapy is the major treatment. Interatrial shunt devices have preliminarily been shown to be safe and efficacious for the treatment of HFpEF, their utilization in nonobstructive hypertrophic cardiomyopathy patients has not been describe

An 89-year-old male case was hospitalized in the COVID-19 department. His computerized chest tomography scan showed nodular opacities with glass halo including peripheral distribution. The patient showed active brucellosis.Finally, his respiratory symptoms and the radiologic images had got better and the second SARS-COV-2 test and the serologic tests were negative

Acharya Balkrishna1, 2, Sumit Kumar Singh1, Rakshit Pathak1, Vedpriya Arya1,21 Patanjali Herbal Research Division, Patanjali Research Institute, Haridwar, Uttarakhand 2494042 Department of Applied and Allied Sciences, University of Patanjali, Haridwar, Uttarakhand.*Correspondence: sumitkumar.singh@prft.in; Patanjali Herbal Research Division, Patanjali Research Institute, Haridwar, Uttarakhand 249404