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Explore 66,105 preprints on the Authorea Preprint Repository

A preprint on Authorea can be a complete scientific manuscript submitted to a journal, an essay, a whitepaper, or a blog post. Preprints on Authorea can contain datasets, code, figures, interactive visualizations and computational notebooks.
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Replication celebration: rewarding replication to improve reproducibility
Hannah Hobson

Hannah Hobson

June 02, 2016
A document by Hannah Hobson. Click on the document to view its contents.
Alfred ICU Journal Club Review of “Pickard et al, 1989: British aneurysm nimodipine t...
Jennifer R. Hastings
Chris Nickson

Jennifer R. Hastings

and 2 more

July 29, 2016
Available from: Pickard, J. D., Murray, G. D., Illingworth, R., Shaw, M. D., Teasdale, G. M., Foy, P. M., … Richards, P. (1989). Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial. BMJ, 298(6674), 636–642. doi:10.1136/bmj.298.6674.636
I am Scott Berinato, senior editor at Harvard Business Review. I'm here to talk anyth...
ScottBerinatoHBR
r/Science AMAs

ScottBerinatoHBR

and 1 more

June 02, 2016
Hi everyone! I’m Scott Berinato, senior editor at Harvard Business Review and author of ​Good Charts​, a new book about dataviz for managers. As a senior editor at HBR, I write for the magazine and website, but also spend a lot of time editing big ideas from academics and others. When I’m not doing that, I’m probably in my garden getting my hands dirty. While most of you on here are at the cutting edge of dataviz trends, there are countless managers who recognize the need to improve themselves beyond the typical ‘click-and-dataviz-and-paste-into-powerpoint’ approach that has dominated the business world for two decades. ​Good Charts​ is meant to help these folks get better at using dataviz, largely through a design-focused approach. Let’s talk about what I’m hearing from executives and non-specialists about what they’re excited about, what they’re intimidated by, and why the first question is still, always, ‘can I use a pie chart?’ I’ll be back at 12pm ET to answer all of your questions. In the meantime, Ask Me Anything! Okay I’m ready to get started. Some great questions already. Let’s get going. Hey, thanks for coming out for this. I’ll check back here the rest of the day and for the rest of the week to answer more questions. Keep up the good and positive work r/DataIsBeautiful!
PLOS Science Wednesday: Hi reddit, my name is Nicholas Money and I published a paper...
PLOSScienceWednesday
r/Science AMAs

PLOSScienceWednesday

and 1 more

June 01, 2016
Hi Reddit, My name is Nicholas Money. I’m a biologist at Miami University in Oxford, Ohio and specialize in the study of fungal growth and reproduction. I am fascinated by the extraordinary mechanisms of spore discharge in these organisms that include high-velocity spurts, exploding gas bubbles, and a catapult that launches mushroom spores. I am the senior author of a 2015 paper in PLOS ONE titled, “Mushrooms as rainmakers: How spores act as nuclei for raindrops”. A couple of years ago I was struck by research by atmospheric chemists that suggested that 50 million tons of fungal spores are ejected into the atmosphere every year. This made me wonder whether the mechanism of drop expansion that powers the discharge of mushroom spores could be reactivated once the spores were airborne. If this happened in clouds, it could play a significant role in the condensation of water and stimulate rainfall. The PLOS ONE paper reports experiments that offer a proof of concept using environmental scanning electron microscopy. This work was co-authored by my doctoral student, Maribeth Hassett, and long-term collaborator Mark Fischer, a physicist at Mount St. Joseph University in Cincinnati. I’ll be answering questions at 1pm ET – Ask Me Anything!
It's not gambling if you never lose
Laura Hershey

Laura Hershey

May 30, 2016
A document by Laura Hershey. Click on the document to view its contents.
Reproducibility in research: How a small field is pioneering a culture of sharing
Richard de Grijs

Richard de Grijs

May 29, 2016
The ‘reproducibility crisis’ in science appears to be a widespread problem that may have its roots in the ‘publish or perish’ culture of the contemporary academy. Facilitated by a well-developed culture of data sharing, in astrophysics opportunities to reproduce or replicate published results have been part of the field’s fabric for many decades. The valuable lessons learned from this small discipline could easily be rolled out to other data-rich disciplines. This essay aims at triggering more extensive discussion of the numerous advantages of data sharing and responsible research attitudes.
Alfred ICU Journal Club Review of “Laursen CB, et al. Point-of-care ultrasonography i...
Matthew Hung
Aidan Burrell

Matthew Hung

and 2 more

May 29, 2016
Article Reviewed Laursen CB, Sloth E, Lassen AT, Christensen Rd, Lambrechtsen J, Madsen PH, Henriksen DP, Davidsen JR, Rasmussen F. Point-of-care ultrasonography in patients admitted with respiratory symptoms: a single-blind, randomised controlled trial. Lancet Respir Med. 2014 Aug;2(8):638-46. doi: 10.1016/S2213-2600(14)70135-3. Epub 2014 Jul 3. PMID: 24998674.
PLOS Science Wednesday: Hi Reddit, we’re Nick and Cori Ruktanonchai, and we published...
PLOSScienceWednesday
r/Science AMAs

PLOSScienceWednesday

and 1 more

May 25, 2016
Hi Reddit! I’m Nick Warren Ruktanonchai, a postdoctoral research fellow at the University of Southampton. I’m interested in understanding how people move, which helps us predict when, where, and why some people become exposed to areas with infectious diseases. And I am Cori Warren Ruktanonchai, a PhD student in Geography & Environment at the University of Southampton–as you may have noticed by the names, I also happen to be Nick’s wife! I’m interested in using spatial statistics to better locate pregnant women, mothers and newborns at risk of adverse health outcomes. We recently published an article titled “Identifying Malaria Transmission Foci for Elimination Using Human Mobility Data” in PLOS Computational Biology, mapping where people got malaria based on their travel patterns. We combined data from 1.19 million mobile phones in Namibia with a map of malaria prevalence to predict areas where the most people get infected. We hope that by targeting these hotspots, elimination efforts can both send help where it’s most needed and reduce transmission nationwide. Call and text locations from mobile phones are a great tool for knowing where people have been. At Flowminder, we’ve used mobile phone data to not only help governments and NGOs predict the spread of disease, we’ve also used it to understand how people move after catastrophes, including a PLOS Medicine paper on the 2010 Haiti earthquake and a PLOS Currents paper on the 2015 Nepal earthquake. We’ll be answering your questions at 1pm ET – Ask Us Anything! Don’t forget to follow Nick on Twitter at @nruktanonchai and Cori at @cwruktanonchai. Also, the Flowminder Foundation can be found at @flowminder, and the WorldPop Project at @WorldPopProject!
Gene-Editing---Is the Quest to Alter a Patient's Genome Ethical?
Megan Yu

Megan Yu

June 07, 2016
Gene-editing---the ability to alter a patient's genome---aims to repair deleterious genes in order to improve patient outcomes. Recent biomedical and social science research, however, has exposed many biological and ethical hurdles that compromise its merits. While gene-editing holds promise to treat many detrimental diseases, it should be approached with caution as it could have unforeseen consequences that should be investigated with further research.
Mistaking the symptom for the disease: preprints in biomedical science
Yarden Katz

Yarden Katz

May 19, 2016
A document by Yarden Katz. Click on the document to view its contents.
Gender and Racial Disparities in Pain Management---A Differentiation Diagnosis
Megan Yu

Megan Yu

June 10, 2016
Abstract: Given that incoming physicians are required to uphold the Hippocratic Oath as they embark on their medical journey, it is expected that they should treat patients to the best of their abilities. Recent biomedical and social science research; however, has demonstrated that gender and racial bias may be playing a subtle yet critical role in the medical decision making process that is affecting the care that many patients deserve. While many of the biological differences among different groups of people of various diseases have been delineated, further research is needed to evaluate how these biological differences are being translated into gender and racial stereotypes in the minds of physicians and how resources that promote the health of all genders and races could be better distributed in order to improve the quality of life of all patients possible.
The Diel Hypothesis and Theory of Evolution
Glen D. Brown

Glen D. Brown

November 26, 2016
A document by Glen D. Brown. Click on the document to view its contents.
Science AMA Series: I’m Ron Garan, Chief Pilot for World View Enterprises and former...
Ron_Garan
r/Science AMAs

Ron_Garan

and 1 more

November 11, 2016
Hi reddit! World View is providing a new perspective of our planet and revolutionising access to space for communications technology, sensors and people. I believe that seeing the Earth from space changes the way we view humanity and our relationship with this planet; I call this ‘The Orbital Perspective’. As a NASA astronaut I travelled 71,075,867 miles in 2,842 orbits of our planet over 178 days. I flew on both the US Space Shuttle and Russian Soyuz spacecraft and logged over 27 hours in the vacuum of space during four spacewalks. I also participated in a record-setting exploration research mission held in Aquarius, the world’s only undersea laboratory and I am the author of ‘The Orbital Perspective’ – my book detailing the effects of seeing Earth from a new point of view. I’ll be talking about The Orbital Perspective and life in space at BBC Future’s World Changing Ideas Summit on 15 November in Sydney. I will be here to answer questions at 15:00pm EST, 20:00pm GMT. Ask me anything!
American Chemical Society AMA: I’m Joe Martino, a Career Consultant for the American...
AmerChemSocietyAMA
r/Science AMAs

AmerChemSocietyAMA

and 1 more

May 11, 2016
A document by AmerChemSocietyAMA . Click on the document to view its contents.
Science AMA Series: We’re the engineers who saved NASA’s planet-hunting Kepler spacec...
Kepler_Mission
r/Science AMAs

Kepler_Mission

and 1 more

May 05, 2016
A document by Kepler_Mission . Click on the document to view its contents.
Science AMA Series: Hi, I’m Joe Palca and I work at National Public Radio (NPR) as a...
joesbigidea
r/Science AMAs

joesbigidea

and 1 more

May 03, 2016
Hi Reddit, I’ve been a science reporter for more than 30 years. I have a PhD in Psychology from UC Santa Cruz. I have worked at Nature, Science, and now NPR. Over the years I’ve traveled around the world covering science stories: from to the South Pole to the top of Mauna Kea, to inside the plume of the Eyjafjallajokull during its eruption in 2010. I’ve been at the Jet Propulsion Laboratory while 5 different probes successfully landed on Mars, I’ve been to Stockholm to watch the King of Sweden award the Nobel prizes, and I’ve interviewed many of the world’s top scientists: Jim Watson, Francis Crick, Carol Greider, Martine Reiss, Andrea Ghez, Roger Angel, Jennifer Doudna…you get the idea. I host a series called Joe’s Big Idea that focuses on the minds and motivations of scientists and inventors. The “Big Idea” is to present science not as a set of discoveries but a process of understanding. Most of the news media depict science lurching from breakthrough to breakthrough. I want to show the hard work, frustration, creativity, persistence and occasionally joy that truly represents what science is all about. Want to see what I’m up to and chat with me after this AMA? Message me and follow me on Facebook at Joe’s Big Idea. I will be back at 1 pm Et to answer your questions, Ask me anything. I am blown away by all the interesting questions. You have set the bar very high. I’ve been writing answers for a couple hours now, and if I could only type faster, I’d answer more. I hope this discussion we started today can continue. I’m very committed to accurate communication of science, and welcome thoughts, ideas, and critiques going forward. I’ll watch /r/Science for questions going forward, or you can get in touch via the Joe’s Big Idea Facebook page or joesbigidea@npr.org
Two steps toward a culture of reproducibility in science
Matthew MacLennan

Matthew MacLennan

June 21, 2016
The following is a short, possibly humorous essay providing two concrete ideas to increase reproducibility in science research. The two ideas are united under the notion of a “culture of reproducibility”. The first idea is hiring different kinds of professionals in the research ecosystem whose job is to ensure reproducibility and impact. The second idea is to require reproducibility risk-management plans in funding applications. Together, these actions are an investment into the infrastructure of research for increased impact and accountability, along with a stronger conception of reproducibility. It will also solve the world energy crisis for under half a million USD by June. No citation software was harmed in the production of this essay.
American Chemical Society AMA: I’m David Constable, Director of the ACS Green Chemist...
AmerChemSocietyAMA
r/Science AMAs

AmerChemSocietyAMA

and 1 more

April 26, 2016
Hi Reddit! Since I introduced myself in the ACS AMA last year (http://redd.it/3fqnqo) , I’ll only say that I’m the Director of the American Chemical Society’s Green Chemistry Institute where we work to catalyze and enable the implementation of green chemistry and engineering throughout the global chemistry enterprise. At the moment we’re getting ready for the 20th Annual Green Chemistry & Engineering Conference, held in Portland, OR June 14-16 (http://www.gcande.org/) and I hope you can join us for what is shaping up to be a great Conference.. So, feel free to ask me anything about the current and future states of sustainable and green chemistry and engineering. Like last year, feel free to ask me anything about how sustainable and green chemistry is implemented in industry, or how you can apply it in your research, or what challenges you’re encountering in your work as you work to implement it. I will be back at 11 am ET to answer your questions, Ask me Anything!
Science AMA Series: I’m Christophe Galfard, a theoretical physicist and author of The...
Christophe_Galfard
r/Science AMAs

Christophe_Galfard

and 1 more

April 24, 2016
Hello Reddit! My name is Dr. Christophe Galfard and I’m a theoretical physicist and author of The Universe In Your Hand. I hold a Ph.D. in Theoretical Physics from Cambridge University where my supervisor was the world-renowned Professor Stephen Hawking. I worked with him on black holes and the origin(s) of our universe for many years. While I’m no longer at Cambridge, I now spend pretty much all my time spreading scientific knowledge to the general public in [hopefully] entertaining ways. From the tiniest particles to the edge of our known universe as well as theoretical scientific attempts to unify all known forces in a Theory of Everything, I seek to help everyone understand the science of our world - as it is seen by today’s scientists. How was our universe formed? Why do stars die and why do some of them become black holes? Our world is filled with mystery, excitement, and questions whose answers still escape the brightest minds to walk on Earth. My goal is to help everyone who wants to learn more about our universe and how it works in a way that anyone is able to understand and grasp. If you’ve ever had a question about the solar system, the Big Bang, dark matter, parallel universes, quarks, or anything else (science related!), now’s the time. I will be back to answer your questions at 3 pm EDT, Ask me anything! Well, there are so many brilliant questions that I’ve left unanswered that I feel a bit bad about it, but it is time for me to wrap this up… I’ll try to come back to answer some of these in the days to come. In the mean time, thank you so much for your questions, I’ve had a great time answering as many as I could! And don’t ever forget to keep asking questions about our beautiful world! Christophe
Deuteronium deuteroxide. The why of pD 7.435.
Henry Rzepa

Henry Rzepa

April 23, 2016
A document by Henry Rzepa. Click on the document to view its contents.
Science AMA Series: Hi Reddit! I’m Eric Green, Director of the National Human Genome...
Eric_Green
r/Science AMAs

Eric_Green

and 1 more

April 22, 2016
Hi Reddit - I’m Eric Green, Director of the National Human Genome Research Institute (NHGRI) since 2009. NHGRI is the largest organization in the world solely dedicated to genomics research, and a part of the National Institutes of Health. I started my career in genomics research in the lab of Dr. Maynard Olson at Washington University, and was then appointed Assistant Professor of Pathology and Genetics and Co-Investigator in the Human Genome Center at Washington University. Two years later, I joined the brand new “Intramural Research Program of the National Center for Human Genome Research”, which was later renamed the National Human Genome Research Institute (NHGRI). Prior to becoming Director of NHGRI, I served as Scientific Director of the NHGRI Intramural Research Program, Chief of the NHGRI Genome Technology Branch, and Director of the NIH Intramural Sequencing Center. During that time, and for almost two decades, my lab was at the forefront of efforts to map, sequence, and understand eukaryotic genomes. I was significantly involved in the Human Genome Project from start to finish. As Director of NHGRI, I am responsible for providing overall leadership of the Institute’s research portfolio and other initiatives. In 2011, we developed a new vision for the future of genomics research, entitled Charting a course for genomic medicine from base pairs to bedside (Nature 470:204-213, 2011). Since that time, I have led the Institute in broadening our research mission, including designing and launching a number of major programs to accelerate the application of genomics to medical care. I’ll be back at 1 pm EST (10 am PST, 6 pm UTC) to answer your questions, ask me anything!
Science AMA Series: We’re experts with the National Society of Genetic Counselors, an...
nsgc_panel
r/Science AMAs

nsgc_panel

and 1 more

April 21, 2016
A document by nsgc_panel . Click on the document to view its contents.
Science AMA Series: I’m Ingrid Borecki and I’m a statistical human geneticist who stu...
Ingrid_Borecki
r/Science AMAs

Ingrid_Borecki

and 1 more

April 20, 2016
A document by Ingrid_Borecki . Click on the document to view its contents.
Science AMA Series: I’m George Church, professor at Harvard and MIT, founder of Perso...
George-Church
r/Science AMAs

George-Church

and 1 more

April 25, 2016
A document by George-Church . Click on the document to view its contents.
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